Results 31 to 40 of about 63,407 (320)

The Evidence Behind the Treatment of Canine Idiopathic Epilepsy [PDF]

, 2016
Oral phenobarbital and imepitoin in particular, followed by potassium bromide and levetiracetam are likely to be effective for the treatment of canine idiopathic epilepsy. There is strong evidence supporting the use of oral phenobarbital and imepitoin as
Brodbelt, D C, Charalambous, M, Volk, H A   +2 more
core   +3 more sources

Combination of antiseizure medications phenobarbital, ketamine, and midazolam reduces soman‐induced epileptogenesis and brain pathology in rats

Epilepsia Open, 2021
Objective Cholinergic‐induced status epilepticus (SE) is associated with a loss of synaptic gamma‐aminobutyric acid A receptors (GABAAR) and an increase in N‐methyl‐D‐aspartate receptors (NMDAR) and amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid ...
Lucille A. Lumley, Brenda Marrero‐Rosado, Franco Rossetti, Caroline R. Schultz, Michael F. Stone, Jerome Niquet, Claude G. Wasterlain   +6 more
doaj   +1 more source

Seizure Disorders in Goats and Sheep. [PDF]

, 2016
BackgroundGoats and sheep are more likely to be presented for examination for seizures than are cattle, possibly as a consequence of their relatively smaller body size.
Aleman, M, Chigerwe, M
core   +1 more source

Behavioral and structural changes in the hippocampus of wistar epileptic rats are minimized by acupuncture associated or not with phenobarbital

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2022
The aim of this study was to analyze the behavior and histopathological changes in the hippocampus of epileptic Wistar rats treated with acupuncture associated or not with phenobarbital.
T.C.C. Silva, A.A. N. Silva, Y.K.V. Serafim, V.A. Silva Júnior, E.R. Lima   +4 more
doaj   +1 more source

Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]

, 2016
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F, Dale, R. C., Hong, M, Jones, H, Mohammad, Ss, Nosadini, M, Pillai, Sc, Sharpe, C   +7 more
core   +1 more source

International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy [PDF]

, 2015
Common criteria for the diagnosis of drug resistance and the assessment of outcome are needed urgently as a prerequisite for standardized evaluation and reporting of individual therapeutic responses in canine epilepsy. Thus, we provide a proposal for the
A Neligan, A Tipold, A Wessmann, Akos Pakozdy, Andrea Fischer, Andrea Tipold, B Callaghan, BD Jovanovic, C Rundfeldt, CA Scorza, CE Stafstrom, CH Gullov, CL Gaskill, Clare Rusbridge, CM Eddy, CW Dewey, DM Boothe, E Ben-Menachem, E Bersan, E Faught, E Perucca, European-Medicines-Agency, G Jacobs, G Zaccara, H Potschka, HA Volk, HE Baird-Heinz, Heidrun Potschka, HJ Cross, Holger A Volk, I Olmez, J Weissl, JA French, JA French, JA Hanley, Jacques Penderis, JF Tellez-Zenteno, JH Rossmeisl, JY Chung, K Orito, Karen Muñana, Kaspar Matiasek, KR Munana, KR Munana, KR Munana, KS Wilcox, L Librizzi, L Rutherford, LK Lord, Luisa De Risio, M Berendt, M Berendt, M Charalambous, M Schwartz, M Sillanpaa, MB Westover, Mette Berendt, MG Neuman, Michael Podell, ML Miller, N Fredso, N Shihab, Ned Patterson, P Kwan, P Ryvlin, PA March, Paul Mandigers, R Monteiro, R Shankar, RE Levitski, RM Packer, Robyn Farquhar, S Balosso, S Balosso, S Klamer, S Steinmetz, SA Kube, SA Moore, Sam Long, Simon Platt, Sofie Bhatti, T Glauser, T Glauser, T Klopmann von, T Klopmann Von, T Pancotto, U Yilmaz, V Hülsmeyer, V Tang, Veronika Stein, W Löscher, WHOQOL-Group T, Wolfgang Löscher, Y Chang   +93 more
core   +15 more sources

MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor. [PDF]

PLoS ONE, 2012
Constitutive androstane receptor (CAR) is a nuclear receptor that regulates the transcription of target genes, including CYP2B and 3A. Phenobarbital activates CAR, at least in part, in an AMP-activated protein kinase (AMPK)-dependent manner. However, the
Ryota Shizu, Sawako Shindo, Takemi Yoshida, Satoshi Numazawa   +3 more
doaj   +1 more source

Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy [PDF]

, 2018
Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease.
A Klang, A Pakozdy, A Pakozdy, A Pakozdy, A Pellegrini, AD Quesnel, Akos Pakozdy, AM Wahle, AS Sawchuk, C Bertolani, CR Hooijmans, CW Dewey, D Hasegawa, D Hughes, D Moher, D Schwartz-Porsche, D Schwartz-Porsche, DB Roye, DE Cuff, DL Zoran, DM Boothe, DM Brewer, G Zaccara, G Zaccara, GE Solomon, GH Guyatt, H Volk, Holger A. Volk, JA Berlin, JA Wada, JAD Gasper, JM Ducote, KE Finnerty, KS Bailey, KS Bailey, LR Barnard, M Charalambous, M Charalambous, M Lowrie, M Podell, MA Cautela, MA Holmes, Marios Charalambous, MB Carnes, MJ Baho, NM van Gelder, O Engel, P Boydell, PN Papanikolaou, R Chou, S Cizinauskas, S Schriefl, S Wagner, SA Center, SD Ross, SF Bhatti, SM Cochrane, SM Cochrane, Sofie F. M. Bhatti   +58 more
core   +3 more sources

Investigation of cross-reactivity between phenobarbital and levetiracetam in children with epilepsy: A prospective, observational multicenter study

Epilepsy & Behavior Reports, 2023
Objectives: Pharmaceutical allergic reactions due to antiseizure medications (ASMs) are one of the major concerns in the management of patients. Finding an alternative ASM which does not cause allergic reactions and has acceptable effectiveness can be ...
Samane Rahimi, Bardia Danaei, Mohammad Mehdi Nasehi, Sasan Saket, Nazanin Farahbakhsh, Maryam Rajabnejad, Mohammad Mehdi Taghdiri   +6 more
doaj   +1 more source

Phenobarbital Pharmacokinetics and Optimal Dosing of Phenobarbital

Pediatric Neurology Briefs, 2018
Researchers from the Baylor College of Medicine in Houston, TX, USA, conducted a retrospective population pharmacokinetic analysis of 355 patients ages less than 19 years of age in the inpatient setting who were initiated on intravenous or oral ...
Safiullah Shareef, Murtaza Nasir Ali
doaj   +1 more source