Results 61 to 70 of about 366,718 (318)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Customizable metal-phenolic supraparticles based on rationally designed building blocks

open access: yes, 2022
Metal-phenolic networks (MPNs) as a versatile platform for particle engineering have been well developed due to their integrated benefits of both metal ions and phenolic molecules.
Junling, Guo   +9 more
core   +1 more source

Chronic vascular effects of oat phenolic acids and avenanthramides in pre- or stage 1 hypertensive adults [PDF]

open access: yes, 2020
Wholegrain consumption is linked to a lower risk of cardiovascular disease. Evidence from randomized controlled trials have established that the consumption of wholegrain oats lowers blood cholesterol, via a mechanism partly mediated by β-glucan soluble ...
Schar, M. Y.   +7 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Antioxidant activity and total phenolic contentof ethyl acetate extract and fractions of Lantana camara L.leaf

open access: yes, 2020
Antioxidant activity and total phenolic contentof ethyl acetate extract and fractions of Lantana camara L ...
suryati, suryati
core  

The phenolic compound content in plants of the family Ericaceae under cryolithozone conditions

open access: yes, 2023
The content of phenolic compounds in the fruits of various plant species of the family Ericaceae, collected on the territory of the Republic of Sakha (Yakutia) during the fruiting period in July–August, was studied. The study confirms that plants growing
Niklaida N. Ivanova   +1 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

CHEMICAL COMPOSITION, VOLATILES, AND ANTIOXIDANT ACTIVITY OF Rosa iberica STEV. hips

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2016
. Rosehip fruits have been known to contain significant amounts of bioactive compounds. These bioactive compounds positively affect human health due to their antioxidant activities.
Zehra Tuğba Abaci   +3 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Helianthemum oelandicum subsp. incanum and Fumana thymifolia: Characterization of LC-ESI-QTOF-MS profiles and their biological activities based on plant parts and extraction solvents

open access: yesKuwait Journal of Science
The members of the genera Helianthemum and Fumana offer great potential for ethnobotanical purposes, including gastrointestinal and reproductive problems.
doaj   +1 more source

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