Results 151 to 160 of about 381,214 (193)

Synergistic Modulating of Mitochondrial Transfer and Immune Microenvironment to Attenuate Discogenic Pain

Advanced Science, EarlyView.
Gallic acid (GA) and copper ions self‐assemble to form nanoparticles, which are then modified with mitochondrial targeting peptides and gap junction modulator. These nanoparticles scavenge mitochondrial reactive oxygen species to induce M2 polarization and enhance intercellular mitochondrial transfer.
Xinzhou Wang, Zhenyu Guo, Linjie Chen, Jing Sun, Kenny Yat Hong Kwan, Morgan Jones, Yan Michael Li, Yangyang Hu, Xueqiang Wang, Pooyan Makvandi, Xiangyang Wang, Qiuping Qian, Yunlong Zhou, Aimin Wu   +13 more
wiley   +1 more source

Phenolic compounds, antioxidant enzymes, and oxidative stress in barley (Hordeum vulgare L.) genotypes under field drought-stress conditions. [PDF]

BMC Plant Biol
Mohagheghian B, Saeidi G, Arzani A.
europepmc   +1 more source

Engineered Genetic Circuits Activated by Bezafibrate Improve ESC‐Based TAA Cancer Vaccine Efficacy and PD‐L1 Nanobody Therapy

Advanced Science, EarlyView.
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin, Shuzhen Liu, Mingshuo Zhan, Jian‐Dong Huang   +3 more
wiley   +1 more source

The Estimation of Phenolic Compounds, Sugars, and Acids of the Cultivar and Clones of Red-Fleshed Apples Based on Image Features. [PDF]

Foods
Ropelewska E, Szwejda-Grzybowska J, Lewandowski M, Mieszczakowska-Frąc M.   +3 more
europepmc   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Oxidation of Small Phenolic Compounds by Mn(IV). [PDF]

Molecules
Gruenberg MG, Halvorson JJ, Hagerman AE, Enoma IG, Schmidt MA.   +4 more
europepmc   +1 more source

Hydrogel‐Transformable Probiotic Powder for Targeted Eradication of Helicobacter pylori with Enhanced Gastric Mucosal Repair and Microbiota Preservation

Advanced Science, EarlyView.
A multifunctional, edible, and hydrogel‐transformable probiotic powder is developed based on the “bacteria‐mediated bacterial eradication” strategy. By leveraging the targeted binding capability of L. reuteri to H. pylori, this approach achieves an integrated therapeutic effect, including bactericidality, anti‐inflammation, gastric mucosal repair, and ...
Yongkang Lai, Hanchun Shen, Shige Wang, Yongliang Ouyang, Xinyuan Zhang, Bin Hu, Xiaoyi Zhang, Guisheng Li, Lizhi Xu, Jiulong Zhao   +9 more
wiley   +1 more source

Characterizations of lactic acid bacteria derived from pickles and the effects of fermentation on phenolic compounds in peony flowers. [PDF]

Food Chem X
Yang Y, Xu Y, He X, Guo M, Chen J, Luo L, Xiang J.   +6 more
europepmc   +1 more source

An Ultra‐Fast Rolling Double‐Helical Robot Driven by Constant Humidity

Advanced Science, EarlyView.
A double‐helical robot named Dualicalbot is proposed to achieve a high‐speed rolling under a constant humidity. The special asymmetric structural design makes sure that the two helices alternately drive the robot to roll with a remarkable speed of 5.8 BL s−1, 4.8 times faster than the fastest robot driven by a constant environment and surpassing the ...
Chuhan Xu, Jiayao Ma, Lei Fu, Xinmeng Liu, Lei Zhang, Yan Chen   +5 more
wiley   +1 more source

Effect of drying methods on phenolic compounds and antioxidant activity of Capparis spinosa L. fruits. [PDF]

BMC Plant Biol
Babaei Rad S, Mumivand H, Mollaei S, Khadivi A.   +3 more
europepmc   +1 more source