Results 11 to 20 of about 6,559 (174)
A 10-Year-Old Boy With Chronic Atrial and Intestinal Dysrhythmia (CAID) and Chronic Intestinal Pseudo-Obstruction (CIPO). [PDF]
Clin Case RepABSTRACT Chronic intestinal pseudo‐obstruction (CIPO) is a severe gastrointestinal syndrome characterized by disruption of normal gut movement, resembling a mechanical obstruction, despite the absence of any physical obstruction. It can occur idiopathically or as a secondary manifestation of various underlying conditions, such as certain genetic ...
Hosseini A +6 more
europepmc +2 more sources
UV-light effects on cytochrome c modulated by the aggregation state of phenothiazines. [PDF]
PLoS ONE, 2013 The present study shows the factors that modulate the photodamage promoted by phenothiazines. Cytochrome c was irradiated with UV light for 120 min, over a pH range from 4.0 to 8.0, in the absence and in the presence of different concentrations of ...
Carolina G dos Santos +7 more
doaj +1 more source
When Antibiotics Leave a Mark: Minocycline-Induced Hyperpigmentation. [PDF]
Clin Case RepBluish discoloration of the dorsal aspects of the hands and nails. ABSTRACT This article presents two patients with significant minocycline‐induced hyperpigmentation, illustrating the diverse clinical manifestations across various body sites. Judicious use of minocycline and early recognition of its adverse effects are crucial to reduce the risk of ...
Ting C +3 more
europepmc +2 more sources
Frontiers in Microbiology, 2020 Calcium ions (Ca2+) play a pivotal role in eukaryote cell signaling and regulate many physiological functions. Although a similar role for Ca2+ in prokaryotes has been difficult to demonstrate, there is increasing evidence for Ca2+ as a cell regulator in
Amy R. Nava +4 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Synthesis of Bioactive Fluorinated 10H-Phenothiazines and their Sulfone Derivatives
E-Journal of Chemistry, 2008 The present communication deals with the synthesis of a series of fluorinated 10H-phenothiazines. 10H-phenothiazines is prepared by Smiles rearrangement of substituted 2-foramido-2´-nitrodiphenylsulfide.
Yogesh Dixit +3 more
doaj +1 more source
Antibiotics, 2013 Phenothiazines have their primary effects on the plasma membranes of prokaryotes and eukaryotes. Among the components of the prokaryotic plasma membrane affected are efflux pumps, their energy sources and energy providing enzymes, such as ATPase, and ...
Leonard Amaral +3 more
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Molecules, 2023 Many new isomeric dipyridothiazine dimers have been presented as molecules with anticancer potential. These compounds were obtained in efficient syntheses of 1,6-, 1,8-, 2,7- and 3,6-diazaphenothiazines with selected alkylaromatic linkers. The structures
Emilia Martula +7 more
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Frontiers in Chemistry, 2020 The study of proteins and mechanisms involved in the apoptosis and new knowledge about cancer's biology are essential for planning new drugs. Tumor cells develop several strategies to gain proliferative advantages, including molecular alterations to ...
Aline Lagoeiro do Carmo +7 more
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Docking and Biological Screening of Bezo[A]phenothiazinones as Novel Inhibitors of Bacterial Peptidogloycan Transpeptidase [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2019 Rising cases of antibiotic-resistant bacteria is a public health concern. Many approved antibiotics target penicillin-binding proteins example peptidoglycan transpeptidase (PTPase). Due to wide pharmacological activity of phenothiazines, new styryl, aryl,
Akachukwu E. Ibezim +2 more
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