Results 11 to 20 of about 36,717 (342)

THE PHENOTHIAZINES

open access: bronzeBritish Journal of Anaesthesia, 1962
J W, DUNDEE, J, MOORE
openaire   +3 more sources

Phenothiazines Modified with the Pyridine Ring as Promising Anticancer Agents

open access: yesLife, 2021
Azaphenothiazines are the largest and most perspective group of modified phenothiazines, and they exhibit variety of biological activities. The review sums up the current knowledge on the anticancer activity of isomeric pyridobenzothiazines and ...
Beata Morak-Młodawska   +2 more
semanticscholar   +1 more source

Determination of pKa values of fluphenazine analogs by reversed-phase high-performance liquid chromatography [PDF]

open access: yesActa Poloniae Pharmaceutica, 2023
Phenothiazine and its derivatives exhibit many properties. Hence they are the starting structures for many new potential drugs, biologically active compounds, dyes, etc.
Sobczak Agnieszka   +3 more
doaj   +1 more source

The Potential of Phenothiazines against Endodontic Pathogens: A Focus on Enterococcus-Candida Dual-Species Biofilm

open access: yesAntibiotics, 2022
Persistent apical periodontitis occurs when the endodontic treatment fails to eradicate the intraradicular infection, and is mainly caused by Gram-positive bacteria and yeasts, such as Enterococcus faecalis and Candida albicans, respectively ...
Nicole de Mello Fiallos   +7 more
doaj   +1 more source

Theoretical Study of 2-(Trifluoromethyl)phenothiazine Derivatives with Two Hydroxyl Groups in the Side Chain-DFT and QTAIM Computations

open access: yesMolecules, 2021
Phenothiazines are known as synthetic antipsychotic drugs that exhibit a wide range of biological effects. Their properties result from the structure and variability of substituents in the heterocyclic system.
Andrzej Poła   +2 more
doaj   +1 more source

Psychoactive Drugs Induce the SOS Response and Shiga Toxin Production in Escherichia coli

open access: yesToxins, 2021
Several classes of non-antibiotic drugs, including psychoactive drugs, proton-pump inhibitors (PPIs), non-steroidal anti-inflammatory drugs (NSAIDs), and others, appear to have strong antimicrobial properties.
John K. Crane   +2 more
doaj   +1 more source

Carbocyanine-Based Fluorescent and Colorimetric Sensor Array for the Discrimination of Medicinal Compounds

open access: yesChemosensors, 2022
Array-based optical sensing is an efficient technique for the determination and discrimination of small organic molecules. This study is aimed at the development of a simple and rapid strategy for obtaining an optical response from a wide range of low ...
Anna V. Shik   +4 more
doaj   +1 more source

14-Substituted Diquinothiazines as a New Group of Anticancer Agents

open access: yesMolecules, 2023
A series of novel double-angularly condensed diquinothiazines with aminoalkyl, amidoalkyl, sulfonamidoalkyl, and substituted phenyl groups was designed, synthesized, and evaluated for their anticancer activity against four selected human tumor cell lines
Małgorzata Jeleń   +7 more
doaj   +1 more source

UV-light effects on cytochrome c modulated by the aggregation state of phenothiazines. [PDF]

open access: yesPLoS ONE, 2013
The present study shows the factors that modulate the photodamage promoted by phenothiazines. Cytochrome c was irradiated with UV light for 120 min, over a pH range from 4.0 to 8.0, in the absence and in the presence of different concentrations of ...
Carolina G dos Santos   +7 more
doaj   +1 more source

Phenothiazines and the electrocardiogram [PDF]

open access: yesPostgraduate Medical Journal, 1975
Summary Fifty-nine (42%) of 140 schizophrenic patients taking phenothiazines were found to have abnormal electrocardiograms. The abnormalities included T wave changes, S-T depression, P-R and Q-T prolongation, persistent sinus tachycardia (110 or more/min) and right bundle branch block.
R. Benson, M. V. Jeeva Raj
openaire   +2 more sources

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