Results 21 to 30 of about 22,216 (274)
Molecules, 2023 Many new isomeric dipyridothiazine dimers have been presented as molecules with anticancer potential. These compounds were obtained in efficient syntheses of 1,6-, 1,8-, 2,7- and 3,6-diazaphenothiazines with selected alkylaromatic linkers. The structures
Emilia Martula +7 more
doaj +1 more source
Molecular characterization of phenothiazines in experimental cancer therapy - New tricks of an old drug revealed [PDF]
, 2012 Cancer is characterized by uncontrolled malignant proliferation of cells that eventually interfere with tissue/organ functions. Traditionally, cancer is treated with chemo- and/or radiotherapy when surgery is not an option. Unfortunately, the efficacy of
Zong, Dali
core +1 more source
Frontiers in Chemistry, 2020 The study of proteins and mechanisms involved in the apoptosis and new knowledge about cancer's biology are essential for planning new drugs. Tumor cells develop several strategies to gain proliferative advantages, including molecular alterations to ...
Aline Lagoeiro do Carmo +7 more
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Simple and simultaneous determination for twelve phenothiazines in human serum by reversed-phase high-performance liquid chromatography [PDF]
, 2007 A high-performance liquid chromatographic method has been developed for the simultaneous analysis of the 12 phenothiazines (chlorpromazine, fluphenazine, levomepromazine, perazine, perphenazine, prochlorperazine, profenamine, promethazine, propericiazine,
Hashimoto Chikako +7 more
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Alcohol Withdrawal – Therapeutical Management in Surgical Patients with Upper Intestinal Bleeding [PDF]
, 2015 Psychological dependence involves a desire to use a drug to avoid the unpleasant withdrawal syndrome that results from cessation of exposure to it. Alcohol withdrawal syndrome is one of the most feared complications of alcohol addiction and sometimes can
Bogdan, Popescu +5 more
core +7 more sources
Non‐Statistical Assembly of Donor–Acceptor Cages for Light‐Induced Charge Separation
Angewandte Chemie, EarlyView.Donor–acceptor functionalized cages [Pd2D2A2]4+ with defined stoichiometry and stereoconfiguration were assembled in a single step by employing the shape complementary assembly (SCA) strategy. While the redox functionalities remain largely independent in the ground state, photoexcitation results in ultrafast ligand‐to‐ligand charge transfer, as ...
Jacopo Tessarolo +6 more
wiley +2 more sources
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden [PDF]
, 2010 Background It has traditionally been thought that the pathological accumulation of tau in Alzheimer's disease and other tauopathies facilitates neurodegeneration, which in turn leads to cognitive impairment.
A de Calignon +38 more
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Docking and Biological Screening of Bezo[A]phenothiazinones as Novel Inhibitors of Bacterial Peptidogloycan Transpeptidase [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2019 Rising cases of antibiotic-resistant bacteria is a public health concern. Many approved antibiotics target penicillin-binding proteins example peptidoglycan transpeptidase (PTPase). Due to wide pharmacological activity of phenothiazines, new styryl, aryl,
Akachukwu E. Ibezim +2 more
doaj
International Journal of Analytical Chemistry, 2009 The presented review is devoted to analytical applications of reactions of Fe(III) and K3[Fe(CN)6] with 2,10-disubstituted phenothiazines (PT). It was found that iron(III) and hexacyanoferrate(III) ions in acidic media easily oxidized PT with the ...
Helena Puzanowska-Tarasiewicz +2 more
doaj +1 more source
Molecules, 2022 Pharmaceuticals carried into space are subjected to different gravitational conditions. Hypergravity is encountered in the first stage, during spacecraft launching.
Ágota Simon +7 more
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