Results 21 to 30 of about 14,571 (257)

Stability Studies of UV Laser Irradiated Promethazine and Thioridazine after Exposure to Hypergravity Conditions

open access: yesMolecules, 2022
Pharmaceuticals carried into space are subjected to different gravitational conditions. Hypergravity is encountered in the first stage, during spacecraft launching.
Ágota Simon   +7 more
doaj   +1 more source

Docking and Biological Screening of Bezo[A]phenothiazinones as Novel Inhibitors of Bacterial Peptidogloycan Transpeptidase [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2019
Rising cases of antibiotic-resistant bacteria is a public health concern. Many approved antibiotics target penicillin-binding proteins example peptidoglycan transpeptidase (PTPase). Due to wide pharmacological activity of phenothiazines, new styryl, aryl,
Akachukwu E. Ibezim   +2 more
doaj  

Synthesis, electronic properties and self-assembly on Au{111} of thiolated (oligo)phenothiazines

open access: yesBeilstein Journal of Organic Chemistry, 2010
(Oligo)phenothiazinyl thioacetates, synthesized by a one-pot sequence, are electrochemically oxidizable and highly fluorescent. SAMs can be readily formed from thiols prepared by in situ deprotection of the thioacetates in the presence of a gold-coated ...
Adam W. Franz   +3 more
doaj   +1 more source

Type IV Pilus-Mediated Inhibition of Acinetobacter baumannii Biofilm Formation by Phenothiazine Compounds

open access: yesMicrobiology Spectrum, 2023
Infections by pathogenic Acinetobacter species represent a significant burden on the health care system, despite their relative rarity, due to the difficulty of treating infections through oral antibiotics.
Nam Vo   +3 more
doaj   +1 more source

Analytical Applications of Reactions of Iron(III) and Hexacyanoferrate(III) with 2,10-Disubstituted Phenothiazines

open access: yesInternational Journal of Analytical Chemistry, 2009
The presented review is devoted to analytical applications of reactions of Fe(III) and K3[Fe(CN)6] with 2,10-disubstituted phenothiazines (PT). It was found that iron(III) and hexacyanoferrate(III) ions in acidic media easily oxidized PT with the ...
Helena Puzanowska-Tarasiewicz   +2 more
doaj   +1 more source

Towards Asymmetrical Methylene Blue Analogues: Synthesis and Reactivity of 3-N′-Arylaminophenothiazines

open access: yesMolecules, 2022
The search for new ways to obtain analogues of the well-known Methylene Blue dye is an important synthetic task. Herein, we proposed and developed an approach to the synthesis of 3-N′-arylaminophenothiazines and asymmetrical 3,7-di(N′-arylamino ...
Alena Khadieva   +5 more
doaj   +1 more source

Trypanosoma cruzi: effect of phenothiazines on the parasite and its interaction with host cells

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Phenothiazines were observed to have a direct effect on Trypanosoma cruzi and on its in vitro interaction with host cells. They caused lysis of trypomastigotes (50 uM/24 h) and,to a lesser extent, epimastigote proliferation.
Solange L. de Castro   +2 more
doaj   +1 more source

Pleiotropic actions of phenothiazine drugs are detrimental to Gram-negative bacterial persister cells

open access: yesCommunications Biology, 2022
Phenothiazines, which have previously been approved as antipsychotic drugs, can also reduce growth and metabolism in a range of Gram-negative bacterial pathogens.
Sayed Golam Mohiuddin   +2 more
doaj   +1 more source

Amplified Sensitivity in SERS Detection of L1CAM With Silver Plasmonic Mesoporous Silica Capsules on an Imprinted Films

open access: yesAdvanced Materials Interfaces, EarlyView.
This study presents core‐shell Au‐Ag NPs and a novel molecularly imprinted polymer (MIP)‐based material targeting L1CAM. Thionine is used as a monomer to create the MIP on a carbon screen‐printed electrode. Functionalized Au‐AgNCs with Raman reporter 4‐mercaptobenzoic acid and anti‐L1CAM enable selective detection via surface‐enhanced Raman scattering ...
Yuselis Castaño‐Guerrero   +6 more
wiley   +1 more source

Photoredox Catalysts Based on N‐(Hexyl)benzothioxanthene‐3,4‐dicarboximide for Photopolymerization and 3D Printing Under Visible Light

open access: yesAngewandte Chemie, EarlyView.
In this work, two benzothioxanthene imide dyes demonstrate excellent photochemical properties. When used as photocatalysts, they work with amine and iodonium salt or sulfonium salt to form different three‐component systems for effectively initiating photopolymerization under visible light, through photoredox catalysis processes.
Bin Song   +10 more
wiley   +2 more sources

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