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Phenotyping the Microcirculation [PDF]
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidney. Both functional and structural alterations in the small arteries, arterioles, and capillaries are the
Struijker-Boudier, Harry A.J.+3 more
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Deficiency of protocadherin 9 leads to reduction in positive emotional behaviour
Protocadherin 9 (Pcdh9) is a member of the cadherin superfamily and is uniquely expressed in the vestibular and limbic systems; however, its physiological role remains unclear.
Masato Uemura+12 more
doaj +1 more source
IntroductionUnderstanding how spike (S)-, nucleoprotein (N)-, and RBD-directed antibody responses evolved in mild and asymptomatic COVID-19 in Africa and their interactions with SARS-CoV-2 might inform development of targeted treatments and vaccines ...
Jennifer Serwanga+31 more
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A Novel Microwave Resonant Sensor for Measuring Cancer Cell Line Aggressiveness
The measurement of biological tissues’ dielectric properties plays a crucial role in determining the state of health, and recent studies have reported microwave biosensing to be an innovative method with great potential in this field.
Livio D’Alvia+6 more
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The Phenotyping Dilemma—The Challenges of a Diversified Phenotyping Community [PDF]
In the past decade, large investments have been made for plant phenotyping in terms of funding, research hours, and high-tech installations in Europe, Australia, North America and Asia. The number of actors in phenotyping has increased rapidly and the focus has gradually shifted from basic to strategic crop research linked to classic agricultural ...
Rosenqvist, Eva+3 more
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Entropic contribution to phenotype fitness [PDF]
All possible phenotypes are not equally accessible to evolving populations. In fact, only phenotypes of large size, i.e. those resulting from many different genotypes, are found in populations of sequences, presumably because they are easier to discover and maintain. Genotypes that map to these phenotypes usually form mostly connected genotype networks
arxiv +1 more source
Breastfeeding and Respiratory Infections in the First 6 Months of Life: A Case Control Study
Background: Viral respiratory tract infections (VRI) are a major reason for hospitalization in children younger than 5 years. A case control study was conducted to investigate the potential role of breastfeeding in protecting children <1 year of age ...
Elisabetta Pandolfi+10 more
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The many roads leading to the syndrome of asthma have proven to be intricately interconnected. The chronic inflammation of asthma is characterized by airway hyperreactivity and variable reversibility. Past classification systems relied on assessment of daily impairment and the distinction between intrinsic (nonallergic) and extrinsic (allergic).
Lanny J. Rosenwasser, Steve Handoyo
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Genetics and Plasticity Are Responsible for Ecogeographical Patterns in a Recent Invasion
Patterns of covariation between phenotype and environment are presumed to be reflective of local adaptation, and therefore translate to a meaningful influence on an individual’s overall fitness within that specific environment.
Katarina C. Stuart+3 more
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Genetic risk factors for Parkinson's disease (PD) risk and progression have been identified from genome-wide association studies (GWAS), as well as studies of familial forms of PD, implicating common variants at more than 90 loci and pathogenic or likely
Katerina Markopoulou+12 more
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