Results 111 to 120 of about 26,955,799 (314)
Enpp2 haploinsufficiency induces an eye-open-at-birth phenotype in the DBA/2 background
microPublication BiologyAutotaxin, encoded by the Enpp2 gene, produces lysophosphatidic acid (LPA), which exerts numerous biological functions via its cognate receptors. Enpp2 null mutant mice die by embryonic day 9.5 owing to aberrant vascular development in the yolk sac ...
Seiichi Koike +2 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
microPublication BiologyAscaridia galli and Ascaridia dissimilis are the most common and economically impactful nematode parasites of commercial poultry. These infections rarely cause clinical disease, but reduction in feed conversion efficiency is detected.
JB Collins +6 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Male fitness and phenotype data
, 2018 Fitness and phenotype data for all males included in our experimental ...
Leigh W. Simmons (261601) +5 more
core +1 more source
Knowledge Discovery in Multi-label Phenotype Data [PDF]
, 2001 The biological sciences are undergoing an explosion in the amount of available data. New data analysis methods are needed to deal with the data. We present work using KDD to analyse data from mutant phenotype growth experiments with the yeast S. cerevisiae to predict novel gene functions. The analysis of the data presented a number of challenges: multi-
Clare, Amanda, King, Ross D
openaire +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Mutations in TGF-beta signaling pathway components regulate the Drosophila melanogaster lifespan
microPublication BiologyThe evolutionary conserved transforming growth factor beta (TGF-β) signaling pathway participates in the regulation of several cellular functions and tissue homeostasis.
Virginia Fife +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Raw phenotype data of grain chalkiness and yield traits for QT12.
Raw phenotype data of grain chalkiness and yield traits for QT12 ...
Li, Wei
core +1 more source