Results 11 to 20 of about 340,700 (262)
Phenotyping the Microcirculation [PDF]
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidney. Both functional and structural alterations in the small arteries, arterioles, and capillaries are the
Struijker-Boudier, Harry A.J. +3 more
openaire +3 more sources
The Phenotyping Dilemma—The Challenges of a Diversified Phenotyping Community [PDF]
In the past decade, large investments have been made for plant phenotyping in terms of funding, research hours, and high-tech installations in Europe, Australia, North America and Asia. The number of actors in phenotyping has increased rapidly and the focus has gradually shifted from basic to strategic crop research linked to classic agricultural ...
Rosenqvist, Eva +3 more
openaire +4 more sources
In silico evidence for the utility of parsimonious root phenotypes for improved vegetative growth and carbon sequestration under drought [PDF]
Drought is a primary constraint to crop yields and climate change is expected to increase the frequency and severity of drought stress in the future. It has been hypothesized that crops can be made more resistant to drought and better able to sequester ...
Farcot, Etienne +11 more
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The autism spectrum disorder (ASD) is an etiologically heterogeneous disorder. Dysfunctions of the intermediate metabolism have been described in some patients. We speculate these metabolic abnormalities are associated with brain insulin resistance (IR),
Melania Manco +6 more
doaj +1 more source
Summary of described phenotypes.
Summary of phenotypes of the different UAS constructs in wild-type (wt), exp reb mutant, and kkv mutant embryos in different overexpression conditions. The phenotypes observed are indicated in black, and light grey indicates absence of the phenotype (TIF)
Giannios, Panagiotis +7 more
core +1 more source
Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood [PDF]
<p>Background: Patterns of wheezing during early childhood may indicate differences in aetiology and prognosis of respiratory illnesses. Improved characterisation of wheezing phenotypes could lead to the identification of environmental influences ...
Heron, J +24 more
core +1 more source
Mapping gene associations in human mitochondria using clinical disease phenotypes [PDF]
Nuclear genes encode most mitochondrial proteins, and their mutations cause diverse and debilitating clinical disorders. To date, 1,200 of these mitochondrial genes have been recorded, while no standardized catalog exists of the associated clinical ...
Curt Scharfe +22 more
core +1 more source
Understanding processes that generate variation between animals and how this variation is inherited between generations is essential for understanding the importance and challenges of estimating genetic values. This chapter describes the standard quantitative genetic model where phenotype values are generated from genetic, environmental, and other ...
Mrode, Raphael +2 more
openaire +1 more source
Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families [PDF]
Recent studies have identified 2 loss-of-function variants, R501X and 2282del4, in the filaggrin gene as predisposing factors in the development of eczema.
Link, Jenny +15 more
core +1 more source

