Results 61 to 70 of about 71,361 (272)
Electronic Journal of Plant Breeding, 2022 In the present investigation, eighteen finger millet genotypes were raised in randomized block design to study about the genetic variability for quantitative traits.
S. Divya1, K. Geetha1*, R. Siva kumar1, A. Nirmala Kumari2 and M. Rajesh2
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Characterisation of sweet stem sorghum genotypes for bio-ethanol production
Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, 2018 In an effort to characterise and select promising sweet stem sorghum genotypes with enhanced biofuel productivity, the present study investigated phenotypic variability present among diverse sweet stem sorghum genotypes based on ethanol production and ...
Precious Mangena +2 more
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Electronic Journal of Plant Breeding, 2017 Assessment of genetic variability using appropriate parameters like phenotypic coefficient of variation (PCV), genotypic coefficient of variation (GCV), heritability (h2), and genetic advance (GA) are really necessary to start an efficient breeding ...
Isong Abasianyanga and, P. Amala Balu
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Phenotypic diversity in natural populations of an endangered plant Tetracentron sinense
Botanical Sciences, 2017 Background: Tetracentron sinense, distributed mainly in central and southwest China, is a threatened deciduous broad-leaved canopy tree. Presently, little is known about the phenotypic diversity in natural populations of T.
Hongyan Han +3 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
International Journal of Bio-Resource and Stress ManagementThe present study was conducted using 124 genotypes of chickpea (Cicer arietinum L.) during rabi, 2019–2020 at Regional Research Station, Faculty of Agriculture, Wadura, Sopore, SKUAST-K to assess the variability, correlation among yield and yield ...
Madhu Saatu +3 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source