Results 11 to 20 of about 1,113,115 (292)

Phenotypic heterogeneity of sitosterolemia [PDF]

Journal of Lipid Research, 2004
Sitosterolemia is a rare autosomal recessive disorder of lipoprotein metabolism characterized by xanthomas and increased plasma concentrations of plant sterols, such as sitosterol.
Jian Wang, Tisha Joy, David Mymin, Jiri Frohlich, Robert A. Hegele   +4 more
doaj   +3 more sources

Phenotypic heterogeneity promotes adaptive evolution. [PDF]

PLoS Biology, 2017
Genetically identical cells frequently display substantial heterogeneity in gene expression, cellular morphology and physiology. It has been suggested that by rapidly generating a subpopulation with novel phenotypic traits, phenotypic heterogeneity (or ...
Zoltán Bódi, Zoltán Farkas, Dmitry Nevozhay, Dorottya Kalapis, Viktória Lázár, Bálint Csörgő, Ákos Nyerges, Béla Szamecz, Gergely Fekete, Balázs Papp, Hugo Araújo, José L Oliveira, Gabriela Moura, Manuel A S Santos, Tamás Székely, Gábor Balázsi, Csaba Pál   +16 more
doaj   +2 more sources

Phenotypic heterogeneity in Streptomyces colonies [PDF]

Current Opinion in Microbiology
Streptomyces are a large genus of multicellular bacteria best known for their prolific production of bioactive natural products. In addition, they play key roles in the mineralisation of insoluble resources, such as chitin and cellulose. Because of their
Rozen, Daniel E., Barona-Gómez, Francisco, Hoskisson, Paul A.   +2 more
core   +8 more sources

Phenotypic heterogeneity of monogenic frontotemporal dementia [PDF]

Frontiers in Aging Neuroscience, 2015
Frontotemporal dementia (FTD) is a genetically and pathologically heterogeneous disorder characterized by personality changes, language impairment and deficits of executive functions associated with frontal and temporal lobe degeneration.
Alberto eBenussi, Alessandro ePadovani, Barbara eBorroni   +2 more
doaj   +5 more sources

Phenotypic Heterogeneity in Mycobacterium tuberculosis

Microbiology Spectrum, 2017
The interaction between the host and the pathogen is extremely complex and is affected by anatomical, physiological, and immunological diversity in the microenvironments, leading to phenotypic diversity of the pathogen.
Neeraj Dhar, John McKinney, Manina, Giulia, Mckinney, John, Giulia Manina, Dhar, Neeraj   +5 more
core   +6 more sources

Phenotypic heterogeneity of MELAS

Molecular Genetics and Metabolism Reports, 2017
Josef Finsterer, Sinda Zarrouk-Mahjoub
doaj   +3 more sources

Enhancing bacterial survival through phenotypic heterogeneity. [PDF]

PLoS Pathogens, 2020
What are the benefits of phenotypic heterogeneity? The ability of bacterial populations to develop phenotypically heterogeneous subpopulations has been recognized for decades.
Leila M Reyes Ruiz, Caitlin L Williams, Rita Tamayo   +2 more
doaj   +2 more sources

The evolutionary advantage of heritable phenotypic heterogeneity [PDF]

Scientific Reports, 2017
Phenotypic plasticity is an evolutionary driving force in diverse biological processes, including the adaptive immune system, the development of neoplasms, and the persistence of pathogens despite drug pressure.
Oana Carja, Joshua B. Plotkin
doaj   +3 more sources

Microbial phenotypic heterogeneity and antibiotic tolerance

Current Opinion in Microbiology, 2007
Phenotypic heterogeneity, defined as metastable variation in cellular parameters generated by epigenetic mechanisms, is crucial for the persistence of bacterial populations under fluctuating selective pressures.
McKinney, John D, Dhar, Neeraj
core   +3 more sources

Editorial: Phenotypic and functional heterogeneity of neutrophils

Frontiers in Immunology, 2023
non ...
Nicola Tamassia, Sebastien Jaillon, Sebastien Jaillon   +2 more
doaj   +4 more sources