Results 31 to 40 of about 94,310 (155)

Phenotypic Plasticity: From Microevolution to Macroevolution [PDF]

, 2014
This chapter starts with a short history of the concept of phenotypic plasticity (from the seventeenth century to present) in order to distinguish two distinct conceptions of plasticity: one more dynamic (or Aristotelian) according to which the notion has been described as a property inherent to life whose very organization depends upon it, and an ...
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Juxtaglomerular Cell Phenotypic Plasticity [PDF]

High Blood Pressure & Cardiovascular Prevention, 2017
Renin is the first and rate-limiting step of the renin-angiotensin system. The exclusive source of renin in the circulation are the juxtaglomerular cells of the kidney, which line the afferent arterioles at the entrance of the glomeruli. Normally, renin production by these cells suffices to maintain homeostasis.
Martini, Alexandre, Danser, Jan
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The New Nitric Oxide Donor, FOR 911B, Induces Relaxation in Isolated Rat Aorta Involving the NO/sGC/cGMP Pathway and K⁺ Channels

Receptors
Background: Nitric oxide (NO) is a gaseous molecule considered to be a protagonist in the dilation of blood vessels, and its property and/or bioavailability are reduced in pathophysiological conditions such as cardiovascular diseases.
Mirelly Cunha da Silva, Florêncio Sousa Gouveia Júnior, Thyago Moreira de Queiroz   +2 more
doaj   +1 more source

Mechanically induced alterations in chromatin architecture guide the balance between cell plasticity and mechanical memory

Frontiers in Cell and Developmental Biology, 2023
Phenotypic plasticity, or adaptability, of a cell determines its ability to survive and function within changing cellular environments. Changes in the mechanical environment, ranging from stiffness of the extracellular matrix (ECM) to physical stress ...
Adrienne K. Scott, Michael Rafuse, Corey P. Neu, Corey P. Neu, Corey P. Neu   +4 more
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Cardiovascular and Renal Effects Induced by Alpha-Lipoic Acid Treatment in Two-Kidney-One-Clip Hypertensive Rats

Biomedicines
α-Lipoic acid (LA) is an antioxidant of endogenous production, also obtained exogenously. Oxidative stress is closely associated with hypertension, which causes kidney injury and endothelial dysfunction.
Déborah Victória Gomes Nascimento, Darlyson Ferreira Alencar, Matheus Vinicius Barbosa da Silva, Danilo Galvão Rocha, Camila Ferreira Roncari, Roberta Jeane Bezerra Jorge, Renata de Sousa Alves, Richard Boarato David, Wylla Tatiana Ferreira e Silva, Lígia Cristina Monteiro Galindo, Thyago Moreira de Queiroz   +10 more
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Plasticity leaves a phenotypic signature during local adaptation

Evolution Letters, 2020
Phenotypic responses to a novel or extreme environment are initially plastic, only later to be followed by genetic change. Whether or not environmentally induced phenotypes are sufficiently recurrent and fit to leave a signature in adaptive evolution is ...
Reinder Radersma, Daniel W.A. Noble, Tobias Uller   +2 more
doaj   +1 more source

Phenotypic plasticity in a population of odonates [PDF]

Scientific Reports, 2018
AbstractThe maintenance of phenotypic plasticity within a species ensures survival through environmental flux. Plastic strategies are increasingly important given the number and magnitude of modern anthropogenic threats to the environment. We tested for phenotypic plasticity in the odonate Argia vivida in response to resource limitation.
Bowman, Randi M., Schmidt, Sharol, Weeks, Chelsea, Clark, Hunter, Brown, Christopher, Latta, Leigh C., Edgehouse, Michael   +6 more
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Impact of Early-Life Brain Injury on Gut Microbiota Composition in Rodents: Systematic Review with Implications for Neurodevelopment

Cells
Early-life brain injuries are major causes of long-term neurodevelopmental disorders such as cerebral palsy. Emerging evidence suggests these injuries can alter the gut microbiota composition, intestinal integrity, and neuroinflammatory responses.
Vanessa da Silva Souza, Raul Manhães-de-Castro, Sabrina da Conceição Pereira, Beatriz Souza de Silveira, Caio Matheus Santos da Silva Calado, Henrique José Cavalcanti Bezerra Gouveia, Jacques-Olivier Coq, Ana Elisa Toscano   +7 more
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Fasting and postprandial Ghrelin levels in Parkinson’s disease: a systematic review and meta-analysis

npj Parkinson's Disease
Parkinson’s disease (PD) is a progressive movement disorder with motor and non-motor symptoms, including gastrointestinal and olfactory dysfunctions. These symptoms may be associated with plasma concentrations of the hormone ghrelin.
Henrique José Cavalcanti Bezerra Gouveia, Osmar Henrique dos Santos-Júnior, Johannes Frasnelli   +2 more
doaj   +1 more source

Cancer cells exhibit clonal diversity in phenotypic plasticity [PDF]

Open Biology, 2017
Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain ...
Robert Austin Mathis, Ethan S. Sokol, Piyush B. Gupta   +2 more
doaj   +1 more source