Results 41 to 50 of about 632,276 (294)

Evolution and maintenance of phenotypic plasticity

Biosystems, 2022
We introduce a novel framework for exploring the evolutionary consequences of phenotypic plasticity (adaptive and non-adaptive) integrating both genic and epigenetic effects on phenotype via stochastic differential equations and in-silico selection. In accordance with the most significant results derived from prior models, we demonstrate how plasticity
UnJin Lee, Emily N. Mortola, Eun-Jin Kim, Manyuan Long   +3 more
openaire   +3 more sources

Patterns of morphological and genetic variability in UK populations of the shore crab, Carcinus maenas Linnaeus, 1758 (Crustacea: Decapoda: Brachyura) [PDF]

, 2006
Previous research has identified extensive inter-population variability in the morphology of the shore crab (Carcinus maenas L.). To determine the source of this variation (genetic or environmental), morphological and genetic data were analysed from ...
Todd, PA, Brian, J.V., Fernandes, T, Ladle, RJ, Brian, JV, Fernandes, T., Ladle, R.J., Todd, P.A.   +7 more
core   +1 more source

The New Nitric Oxide Donor, FOR 911B, Induces Relaxation in Isolated Rat Aorta Involving the NO/sGC/cGMP Pathway and K⁺ Channels

Receptors
Background: Nitric oxide (NO) is a gaseous molecule considered to be a protagonist in the dilation of blood vessels, and its property and/or bioavailability are reduced in pathophysiological conditions such as cardiovascular diseases.
Mirelly Cunha da Silva, Florêncio Sousa Gouveia Júnior, Thyago Moreira de Queiroz   +2 more
doaj   +1 more source

Juxtaglomerular Cell Phenotypic Plasticity [PDF]

High Blood Pressure & Cardiovascular Prevention, 2017
Renin is the first and rate-limiting step of the renin-angiotensin system. The exclusive source of renin in the circulation are the juxtaglomerular cells of the kidney, which line the afferent arterioles at the entrance of the glomeruli. Normally, renin production by these cells suffices to maintain homeostasis.
Martini, Alexandre, Danser, Jan
openaire   +2 more sources

Temperature acclimatisation of swimming performance in the European Queen Scallop [PDF]

, 2005
The phenotypic plasticity of muscle performance and locomotory physiology allows the maintenance of essential activity capacity in the face of environmental change, and has been demonstrated in a wide phylogenetic range of eurythermal vertebrates.
Bailey, DM, Bailey, D.M., Johnston, I.A., Johnston, Ian Alistair   +3 more
core   +1 more source

Cardiovascular and Renal Effects Induced by Alpha-Lipoic Acid Treatment in Two-Kidney-One-Clip Hypertensive Rats

Biomedicines
α-Lipoic acid (LA) is an antioxidant of endogenous production, also obtained exogenously. Oxidative stress is closely associated with hypertension, which causes kidney injury and endothelial dysfunction.
Déborah Victória Gomes Nascimento, Darlyson Ferreira Alencar, Matheus Vinicius Barbosa da Silva, Danilo Galvão Rocha, Camila Ferreira Roncari, Roberta Jeane Bezerra Jorge, Renata de Sousa Alves, Richard Boarato David, Wylla Tatiana Ferreira e Silva, Lígia Cristina Monteiro Galindo, Thyago Moreira de Queiroz   +10 more
doaj   +1 more source

Mechanically induced alterations in chromatin architecture guide the balance between cell plasticity and mechanical memory

Frontiers in Cell and Developmental Biology, 2023
Phenotypic plasticity, or adaptability, of a cell determines its ability to survive and function within changing cellular environments. Changes in the mechanical environment, ranging from stiffness of the extracellular matrix (ECM) to physical stress ...
Adrienne K. Scott, Michael Rafuse, Corey P. Neu, Corey P. Neu, Corey P. Neu   +4 more
doaj   +1 more source

Ecological genetics of an induced plant defense against herbivores: additive genetic variance and costs of phenotypic plasticity [PDF]

, 2002
Adaptive phenotypic plasticity in chemical defense is thought to play a major role in plant-herbivore interactions. We investigated genetic variation for inducibility of defensive traits in wild radish plants and asked if the evolution of induction is ...
Johnson, M. T. J., Marc T. J. Johnson, Conner, J. K., Jeffrey K. Conner, Anurag A Agrawal, Wallsgrove, R. M., Anurag A. Agrawal, Marc T J Johnson, Agrawal, A. A., Roger Wallsgrove, Jeffrey K Conner   +10 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Plasticity leaves a phenotypic signature during local adaptation

Evolution Letters, 2020
Phenotypic responses to a novel or extreme environment are initially plastic, only later to be followed by genetic change. Whether or not environmentally induced phenotypes are sufficiently recurrent and fit to leave a signature in adaptive evolution is ...
Reinder Radersma, Daniel W.A. Noble, Tobias Uller   +2 more
doaj   +1 more source