Results 61 to 70 of about 94,310 (155)

Overcoming maladaptive plasticity through plastic compensation

open access: yesCurrent Zoology, 2013
Most species evolve within fluctuating environments, and have developed adaptations to meet the challenges posed by environmental heterogeneity. One such adaptation is phenotypic plasticity, or the ability of a single genotype to produce multiple ...
Matthew R.J. MORRIS, Sean M. ROGERS
doaj  

EMT-driven plasticity prospectively increases cell–cell variability to promote therapeutic adaptation in breast cancer

open access: yesCancer Cell International
Cellular plasticity enables cancer cells to adapt non-genetically, thereby preventing therapeutic success. The epithelial-mesenchymal transition (EMT) is a type of plasticity linked to resistance and metastasis.
Lauriane Muller   +11 more
doaj   +1 more source

Phenotypic Plasticity of the Drosophila Transcriptome

open access: yesPLoS Genetics, 2012
Phenotypic plasticity is the ability of a single genotype to produce different phenotypes in response to changing environments. We assessed variation in genome-wide gene expression and four fitness-related phenotypes of an outbred Drosophila melanogaster population under 20 different physiological, social, nutritional, chemical, and physical ...
Zhou, Shanshan   +4 more
openaire   +5 more sources

Changes in selection regime cause loss of phenotypic plasticity in planktonic freshwater copepods.

open access: yesPLoS ONE, 2014
Rapid phenotypic adaptation is critical for populations facing environmental changes and can be facilitated by phenotypic plasticity in the selected traits.
Sergej Vital'evič Sereda   +2 more
doaj   +1 more source

Phenotypic Plasticity [PDF]

open access: yes, 2008
J. Howard Frank   +93 more
  +5 more sources

Epigenetic Control of Phenotypic Plasticity in the Filamentous Fungus Neurospora crassa

open access: yesG3: Genes, Genomes, Genetics, 2016
Phenotypic plasticity is the ability of a genotype to produce different phenotypes under different environmental or developmental conditions. Phenotypic plasticity is a ubiquitous feature of living organisms, and is typically based on variable patterns ...
Ilkka Kronholm   +2 more
doaj   +1 more source

Adaptive phenotypic plasticity: consensus and controversy

open access: yesTrends in Ecology & Evolution, 1995
Phenotypic plasticity is an environmentally based change in the phenotype. Understanding the evolution of adaptive phenotypic plasticity has been hampered by dissenting opinions on the merits of different methods of description, on the underlying genetic mechanisms, and on the way that plasticity is affected by natural selection in a heterogeneous ...
Via, S.   +5 more
openaire   +3 more sources

The evolution of phenotypic plasticity: Genealogy of a debate in genetics [PDF]

open access: yesStudies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 2015
The paper describes the context and the origin of a particular debate that concerns the evolution of phenotypic plasticity. In 1965, British biologist A. D. Bradshaw proposed a widely cited model intended to explain the evolution of norms of reaction, based on his studies of plant populations.
openaire   +3 more sources

Epigenetic mechanisms of plasticity and resistance in glioblastoma: therapeutic targets and implications

open access: yesFrontiers in Epigenetics and Epigenomics
Glioblastoma (GBM), a highly aggressive and malignant form of primary adult brain cancer, poses significant therapeutic challenges. Despite our improved understanding of the cellular and molecular mechanisms underlying tumorigenesis and the evolution of ...
Farzaneh Amirmahani   +2 more
doaj   +1 more source

A Natural Major Module Confers the Trade‐Off between Phenotypic Mean and Plasticity of Grain Chalkiness in Rice

open access: yesAdvanced Science
A critical challenge in crop breeding is the trade‐off between improving the mean of an important trait and maintaining its phenotypic plasticity. Grain chalkiness is a key cereal grain‐quality trait highly susceptible to environments.
Juncheng Zhang   +10 more
doaj   +1 more source

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