Results 61 to 70 of about 632,276 (294)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Functional Mapping of Phenotypic Plasticity of Staphylococcus aureus Under Vancomycin Pressure

Frontiers in Microbiology, 2021
Phenotypic plasticity is the exhibition of various phenotypic traits produced by a single genotype in response to environmental changes, enabling organisms to adapt to environmental changes by maintaining growth and reproduction. Despite its significance
Dengcheng Yang, Xuyang Zheng, Libo Jiang, Libo Jiang, Meixia Ye, Meixia Ye, Xiaoqing He, Xiaoqing He, Yi Jin, Yi Jin, Rongling Wu, Rongling Wu, Rongling Wu   +12 more
doaj   +1 more source

Generalized Norms of Reaction for Ecological Developmental Biology [PDF]

, 2002
A standard norm of reaction (NoR) is a graphical depiction of the phenotypic value of some trait of an individual genotype in a population as a function of an environmental parameter. NoRs thus depict the phenotypic plasticity of a trait. The topological
Sarkar, Sahotra, Fuller, Trevon
core  

Moreno et al 2019 phenotypic plasticity JAVBIO

, 2019
Dataset of the scientific article "Phenotypic plasticity in breeding plumage signals in both sexes of a migratory bird: responses to breeding conditions".Peer ...
Moreno Klemming, Juan, López-Arrabé, Jimena, Cantarero, Alejandro, Plaza Cusine, Mireia   +3 more
core   +1 more source

Adaptive plasticity in the mouse mandible [PDF]

, 2014
Background: Plasticity, i.e. non-heritable morphological variation, enables organisms to modify the shape of their skeletal tissues in response to varying environmental stimuli.
Sabrina Renaud, Rayfied, Ej., Rayfield, Emily J, Philip SL Anderson, Renaud, Sabrina, Anderson, Philip S L, Anderson, P., Emily J Rayfield   +7 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Phenotypic plasticity in a population of odonates [PDF]

Scientific Reports, 2018
AbstractThe maintenance of phenotypic plasticity within a species ensures survival through environmental flux. Plastic strategies are increasingly important given the number and magnitude of modern anthropogenic threats to the environment. We tested for phenotypic plasticity in the odonate Argia vivida in response to resource limitation.
Bowman, Randi M., Schmidt, Sharol, Weeks, Chelsea, Clark, Hunter, Brown, Christopher, Latta, Leigh C., Edgehouse, Michael   +6 more
openaire   +2 more sources

The genetics of thermal plasticity in Plantago lanceolata [PDF]

, 2017
Phenotypic plasticity, an individual’s phenotypic response to environmental change, is a fundamental characteristic of all life on earth that plays a central role in adaptation, phenotypic differentiation, and speciation. Temperature-sensitive phenotypic
Marshall, Matthew M., NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Phenotypic plasticity is a negative, though weak, predictor of the commonness of 105 grassland species [PDF]

, 2016
Aim The usual hypothesis about the relationship between niche breadth and range size posits that species with the capacity to use a wider range of resources or to tolerate a greater range of environmental conditions should be more widespread. In plants,
Daniel Prati, Petr Dostál, Markus Fischer, Prati, Daniel, Fischer, Markus, Dostál, Petr   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source