Results 51 to 60 of about 632,276 (294)
The role of phenotypic plasticity in the colonization of novel environments [PDF]
, 2013 Biological invasions have been argued to be facilitated by phenotypic plasticity. Although experiments have shown plasticity can be adaptive, our current understanding is limited to comparative studies that measure plasticity between invasive and non ...
NC DOCKS at The University of North Carolina at Greensboro +1 more
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
CellsEarly-life brain injuries are major causes of long-term neurodevelopmental disorders such as cerebral palsy. Emerging evidence suggests these injuries can alter the gut microbiota composition, intestinal integrity, and neuroinflammatory responses.
Vanessa da Silva Souza +7 more
doaj +1 more source
Ecological consequences of phenotypic plasticity [PDF]
Trends in Ecology & Evolution, 2005 Phenotypic plasticity is widespread in nature, and often involves ecologically relevant behavioral, physiological, morphological and life-historical traits. As a result, plasticity alters numerous interactions between organisms and their abiotic and biotic environments.
Miner, Benjamin G +4 more
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
npj Parkinson's DiseaseParkinson’s disease (PD) is a progressive movement disorder with motor and non-motor symptoms, including gastrointestinal and olfactory dysfunctions. These symptoms may be associated with plasma concentrations of the hormone ghrelin.
Henrique José Cavalcanti Bezerra Gouveia +2 more
doaj +1 more source
Does plasticity enhance or dampen phenotypic parallelism? A test with three lake-stream stickleback pairs [PDF]
, 2016 Parallel (and convergent) phenotypic variation is most often studied in the wild, where it is difficult to disentangle genetic vs. environmentally induced effects.
Oke, K.B. +7 more
core +1 more source
Drivers of phenotypic plasticity in a forest tree [Dataset]
, 2022 [EN] These project improve our understanding of the microevolutionary drivers of phenotypic plasticity, a critical process for resilience of long-lived species under climate change, and support decision making in tree genetic improvement programs and ...
Mata Pombo, Raúl de la
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Cancer cells exhibit clonal diversity in phenotypic plasticity [PDF]
Open Biology, 2017 Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain ...
Robert Austin Mathis +2 more
doaj +1 more source