Results 101 to 110 of about 188,733 (294)
Frontiers in Plant Science, 2020 Leaf shape is an important agronomic trait for constructing an ideal plant type in rice, and high-density genetic map is facilitative in improving accuracy and efficiency for quantitative trait loci (QTL) analysis of leaf trait.
Yi Wen +23 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2019 Variance components, phenotypic means (and sample sizes (n) used in evaluating six morphological traits in Savannah Sparrows from the Champlain Valley of Vermont, 2002–2014 (VP = Phenotypic variance =, VA = additive genetic variance =, and VR = residual ...
Steven E. Travis (4814637) +2 more
core +1 more source
Transgenerational Plasticity and Bet-Hedging: A Framework for Reaction Norm Evolution
Frontiers in Ecology and Evolution, 2020 Decision-making under uncertain conditions favors bet-hedging (avoidance of fitness variance), whereas predictable environments favor phenotypic plasticity.
Jens Joschinski, Dries Bonte
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Differences in phenotypic variance between old and young congeneric species on a small island
, 2023 <p><em>Aim</em>: Insular environments theoretically promote within-species phenotypic variance, in part but not only because insular species enjoy a lower number of trophic interactions than their mainland counterparts.
Péron, Guillaume, Vollot, Benjamin
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Genetic Variability and Correlation Studies in elite ‘B’ and ‘R’ lines in Kharif Sorghum [PDF]
Electronic Journal of Plant Breeding, 2010 The genetic variability and nature of character association was studied in 20 B lines and 16 R lines of kharif sorghum(sorghum bicolor (L) Moench). The genotypic variance was lower than the phenotypic variance for all the characters.High genotypic and ...
A.R. Godbharle, A.W.More and S.S. Ambekar
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Non-chromosomal information enhances the fraction of phenotypic variance explained.
, 2015 Three linear models with different complexity are applied to measure the fraction of phenotypic variance. The first model (simple) includes only the gene deletion status (red), the second model (additive) considers the gene deletion status and non ...
Mohamed El Anbari (686681) +2 more
core +1 more source