Results 81 to 90 of about 425,330 (380)

Rapid one-step separation and purification of recombinant phenylalanine dehydrogenase in aqueous two-phase systems [PDF]

, 2008
Background: Phenylalanine dehydrogenase (PheDH; EC 1.4.1.20) is a NAD +-dependent enzyme that performs the reversible oxidative deamination of L-phenylalanine to phenylpyruvate.
Mohammadi, H.S., Omidinia, E., Taherkhani, H.   +2 more
core  

Review

, 2020
The chalcogen elements oxygen, sulfur, and selenium are essential constituents of side chain functions of natural amino acids. Conversely, no structural and biological function has been discovered so far for the heavier and more metallic tellurium ...
Agh R, Arai K, Baskakov IV, Creighton TE, Dittmer K, Du Vigneaud V, Janeček J, Metanis N, Musiol HJ, Muttenthaler M, Nygard B, O'Donnell ME, Welch M, Yang F   +13 more
core   +1 more source

Identification of critical residues of the serotype modifying O-acetyltransferase of Shigella flexneri [PDF]

, 2016
BACKGROUND Thirteen serotypes of Shigella flexneri (S. flexneri) have been recognised, all of which are capable of causing bacillary dysentery or shigellosis. With the emergence of the newer S.
Thanweer, Farzaana, Verma, Naresh K
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Comparison of Phenolic Compounds, Carotenoids, Amino Acid Composition, In Vitro Antioxidant and Anti-Diabetic Activities in the Leaves of Seven Cowpea (Vigna unguiculata) Cultivars

Foods, 2020
Cowpea is a well-known nutrition rich African leafy vegetable that has potential to sustain food and nutrition insecurity in sub-Saharan Africa. Consumption of cowpea legumes is associated with reduced risk of type 2 diabetes mellitus.
Mapula R. Moloto, Anh Dao T. Phan, Jerry L. Shai, Yasmina Sultanbawa, Dharini Sivakumar   +4 more
doaj   +1 more source

Two Adjacent Phenylalanines In the NMDA Receptor GluN2A Subunit M3 Domain Interactively Regulate Alcohol Sensitivity and Ion Channel Gating [PDF]

, 2017
The N-methyl-d-aspartate (NMDA) receptor is a key target of ethanol action in the central nervous system. Alcohol inhibition of NMDA receptor function involves small clusters of residues in the third and fourth membrane-associated (M) domains.
Dwyer, Donard S., Peoples, Robert W., Ren, Hong, Wu, Man, Zhao, Yulin   +4 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Role of tyrosine M210 in the initial charge separation of reaction centers of Rhodobacter sphaeroides [PDF]

, 1990
Femtosecond spectroscopy was used in combination with site-directed mutagenesis to study the influence of tyrosine M210 (YM210) on the primary electron transfer in the reaction center of Rhodobacter sphaeroides.
Allen J. P., Becker M., Breton J., Bylina E. J., Bylina E. J., Chang C. H., Christoph Lauterwasser, Deisenhofer J., Dieter Oesterhelt, Farchaus J., Feher G., Gray K. A., Holzapfel W., Holzapfel W., Kevin A. Gray, Kirmaier C., Kirmaier C., Kirmaier C., Okamura Y., Parson W., Parson W. W., Rees D. C., Stilz H. U., Tiede D. M., Ulrich Finkele, Wolfgang Zinth   +25 more
core   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Electrochemical Enantiomer Recognition Based on sp³-to-sp² Converted Regenerative Graphene/Diamond Electrode

Nanomaterials, 2018
It is of great significance to distinguish enantiomers due to their different, even completely opposite biological, physiological and pharmacological activities compared to those with different stereochemistry.
Jingyao Gao, Haoyang Zhang, Chen Ye, Qilong Yuan, Kuan W. A. Chee, Weitao Su, Aimin Yu, Jinhong Yu, Cheng-Te Lin, Dan Dai, Li Fu   +10 more
doaj   +1 more source