Results 121 to 130 of about 38,679 (221)

Screening and mutation analysis of phenylalanine hydroxylase deficiency in newborns from Jiangxi province. [PDF]

Front Genet, 2023
Zeng B, Lu Q, Chen S, Guan H, Xu X, Zou Y, Wang F, Huang S, Liu Y, Yang B.   +9 more
europepmc   +1 more source

Insights into glandular trichome biology from analysis of organ‐specific gene expression programmes in cannabis, hop and tomato

The Plant Journal, Volume 125, Issue 6, March 2026.
Significance Statement This study of three glandular trichome‐producing species (cannabis, hop and tomato) defines tissue‐specific transcriptomic atlases for five organs (trichome, flower, leaf, stem and root), providing co‐expression and gene regulatory networks and identifying candidate regulators of specialised metabolism in trichomes of each ...
Muluneh Tamiru‐Oli, Bhavna Hurgobin, Oliver Berkowitz, Lingling Yin, Ricarda Jost, Sofya Gvaramiya, Matthew Welling, Monika S. Doblin, Antony Bacic, James Whelan, Mathew G. Lewsey   +10 more
wiley   +1 more source

Hepatocyte Transplantation Using the Domino Concept in a Child with Tetrabiopterin Nonresponsive Phenylketonuria

Cell Transplantation, 2012
Phenylketonuria is a metabolic disease caused by phenylalanine hydroxylase deficiency. Treatment is based on a strict natural protein-restricted diet that is associated with the risk of malnutrition and severe psychosocial burden.
X. Stéphenne, F. G. Debray, F. Smets, N. Jazouli, G. Sana, T. Tondreau, R. Menten, P. Goffette, F. Boemer, R. Schoos, S. W. Gersting, M. Najimi, A. C. Muntau, P. Goyens, E. M. Sokal M.D., Ph.D.   +14 more
doaj   +1 more source

In Silico Structural Protein Evaluation of the Phenylalanine Hydroxylase p.(Tyr77His) Variant Associated with Benign Hyperphenylalaninemia as Identified through Mexican Newborn Screening. [PDF]

Children (Basel), 2023
Vela-Amieva M, Alcántara-Ortigoza MA, González-Del Angel A, Ibarra-González I, Fernández-Hernández L, Guillén-López S, López-Mejía L, Fernández-Lainez C.   +7 more
europepmc   +1 more source

Deubiquitinase USP19 extends the residual enzymatic activity of phenylalanine hydroxylase variants. [PDF]

Sci Rep, 2022
Sarodaya N, Tyagi A, Kim HJ, Kang JS, Singh V, Hong SH, Kim WJ, Kim KS, Ramakrishna S.   +8 more
europepmc   +1 more source

Thermodynamics of iron, tetrahydrobiopterin, and phenylalanine binding to phenylalanine hydroxylase from Chromobacterium violaceum. [PDF]

Arch Biochem Biophys, 2022
Li M, Subedi BP, Fitzpatrick PF, Emerson JP.   +3 more
europepmc   +1 more source

Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase. [PDF]

Int J Mol Sci, 2022
Conde-Giménez M, Galano-Frutos JJ, Galiana-Cameo M, Mahía A, Victor BL, Salillas S, Velázquez-Campoy A, Brito RMM, Gálvez JA, Díaz-de-Villegas MD, Sancho J.   +10 more
europepmc   +1 more source

Comparative transcriptomic and metabolomic analysis reveals mechanisms of selenium-regulated anthocyanin synthesis in waxy maize (Zea mays L.)

Frontiers in Plant Science
Anthocyanins in maize (Zea mays L.) kernels determine the plant’s color and can enhance its resistance. Selenium (Se) significantly impacts plant growth, development, and secondary metabolic regulation.
Guangyu Guo, Guangyu Guo, Yufeng Wang, Baoku Zhang, Haoran Yu, Liang Li, Guanglu Cao, Baicui Chen, Chengxin Li, Fanshan Bu, Song Teng, Qingtao Yu, Mingbo Gao, Baiwen Jiang, Kejun Yang   +14 more
doaj   +1 more source

Phenylalanine hydroxylase contributes to serotonin synthesis in mice. [PDF]

FASEB J, 2021
Mordhorst A, Dhandapani P, Matthes S, Mosienko V, Rothe M, Todiras M, Self J, Schunck WH, Schütz A, Bader M, Alenina N.   +10 more
europepmc   +1 more source

Melatonin mediates phenolic acids accumulation in barley sprouts under MeJA stress

Frontiers in Nutrition
Phenolic acids are secondary metabolites in higher plants, with antioxidant, anticancer, and anti-aging effects on the human body. Therefore, foods rich in phenolic acids are popular.
Xin Tian, Renjiao Zhang, Zhengfei Yang, Jiangyu Zhu, Weiming Fang, Runqiang Yang, Yongqi Yin   +6 more
doaj   +1 more source