Results 61 to 70 of about 16,453 (233)

In vivo and in silico models of Drosophila for Parkinson's disease

The FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur, Rachel Strazdins, Souvarish Sarkar, Tunahan Çakır   +3 more
wiley   +1 more source

The toxic effects of meta‐tyrosine are related to its misincorporation into the proteome and to altered metabolism in cyanobacteria

The FEBS Journal, EarlyView.
This study reveals that meta‐tyrosine (m‐Tyr), a nonproteinogenic analog of aromatic amino acids, disrupts protein synthesis and photosynthesis in cyanobacteria by being misincorporated by Phenylalanyl‐tRNA synthetase (PheRS) into essential proteins. Through molecular, biochemical, and proteomic analyses in Synechocystis, the research shows that m‐Tyr ...
Hagit Zer, Roei Matan, David Rasin, Yoram Soroka, Noa Carmi, Hanan Schoffman, Nir Keren, Jörg Nickelsen, Oren Ostersetzer‐Biran   +8 more
wiley   +1 more source

Change Your Diet: How CO2, Plant Phenology and Genotype Alter Grapevine Quality and Affect Performance and Larval Transcriptome of an Insect Herbivore

Molecular Ecology, EarlyView.
ABSTRACT Herbivorous insects need to cope with changing host plant biochemistry caused by abiotic and biotic impacts, to meet their dietary requirements. Larvae of the multivoltine European grapevine moth Lobesia botrana, one of the main insect pests in viticulture, feed on both flowers and berries.
Christine Becker, Christof B. Steingass, Heiko Vogel, Annette Reineke   +3 more
wiley   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel, Francis Poirier‐Gravel, Marie‐Ève Paré, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Dominique Michaud, Marc‐André D'Aoust   +9 more
wiley   +1 more source

Trastornos neurológicos a consecuencia de la mutación del gen que codifica para fenilalanina hidroxilas

Revista Ciencias Biomédicas, 2013
Introduction: Phenylketonuria (PKU) is an error of the metabolism of the amino acids due to the gene mutation that codifies for the enzyme called phenylalanine hydroxylase (PAH). 564 cases of mutations in different exons have been reported.
Alvear-Sedán Ciro, Barboza-Ubarnes Miriam, Stave-Salgado Karen   +2 more
doaj  

Food Regime for Phenylketonuria: Presenting Complications and Possible Solutions

Journal of Multidisciplinary Healthcare, 2022
Sudipt Kumar Dalei, Nidhi Adlakha Regional Center for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, IndiaCorrespondence: Nidhi Adlakha Email nidhi.adlakha@rcb.res.inAbstract: In the category of rare inherited genetic disorders ...
Kumar Dalei S, Adlakha N
doaj  

A model for the adaptation of Euryale ferox leaves to aquatic environments through EfCGT1‐controlled flavonoid C‐glycoside‐specific accumulation in epidermis cells

Plant Biotechnology Journal, EarlyView.
Summary With changes in complex environments, plants, especially their leaves, are constantly adapting. Aquatic plants face more diverse and harsh survival situations. However, their adaptive mechanisms are largely unknown. Euryale ferox is a floating leaf aquatic plant characterized by large and rapidly expanding leaves that serve as a model for ...
Ailian Liu, Chenyan Qu, Wenjing Ling, Tianyu Wang, Yanyan Zhang, Yuerui Fang, Yuda Guo, Mengnan He, Jinping Zou, Shuping Zhao, Kai Feng, Peng Wu, Liangjun Li   +12 more
wiley   +1 more source

A near‐gapless genome assembly of Pseudocydonia sinensis uncovers unique phenylpropanoid pathways

Plant Biotechnology Journal, EarlyView.
Summary Pseudocydonia sinensis, commonly known as Chinese quince, belongs to the Rosaceae family and is closely related to apple and pear. Despite its botanical significance, genomic resources for this species remain limited. We present a high‐quality, chromosome‐scale, and haplotype‐resolved genome assembly of P.
Yangxin Zhang, Shuangyu Zhang, Wenmeng Guo, Yuxin Zhang, Xiangxiang Chen, Qiaoming Yu, Yunxiao Liu, Yaqiang Sun, Ke Yu, Houhua Li, Fengwang Ma, Tao Zhao   +11 more
wiley   +1 more source

A novel function for the transcription factor sensitive to proton rhizotoxicity1 in promoting anthocyanin accumulation in strawberry

Plant Biotechnology Journal, EarlyView.
Summary Sensitive to proton rhizotoxicity1 (STOP1), a C2H2‐type zinc finger transcription factor, has been widely studied as a core transcription factor in adapting plants to diverse environmental stresses. However, whether STOP1 regulates anthocyanin accumulation in plants is still unknown.
Ruiqing Bian, Jinxiang Yao, Yuxin Nie, Yuying Zhang, Zhengjia Wu, Junxiang Zhang, Zhihong Zhang   +6 more
wiley   +1 more source

A unique dual activity amino acid hydroxylase in Toxoplasma gondii.

PLoS ONE, 2009
The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes encoding tyrosine hydroxylase; that produces L-DOPA. The encoded enzymes metabolize phenylalanine as well as tyrosine with substrate preference for tyrosine.
Elizabeth A Gaskell, Judith E Smith, John W Pinney, Dave R Westhead, Glenn A McConkey   +4 more
doaj   +1 more source