Haemodynamic Changes After Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine Versus Placebo During Induction of General Anaesthesia: A Randomised Trial. [PDF]
Acta Anaesthesiol ScandABSTRACT Background Ephedrine, phenylephrine, and norepinephrine are commonly used to manage hypotension during the induction of anaesthesia. The objective of this study was to evaluate whether prophylactic administration of assumed equipotent doses of these vasopressors could maintain systolic arterial blood pressure (SAP) and heart rate (HR) within ...
Sjøen GH +4 more
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A comparative study on the effect of dopamine vs phenylephrine in improving the cutaneous analgesic effect of mexiletine in rats [PDF]
Perioperative Medicine, 2023 Background The present study aimed to compare the effects of the combined administration of two adjuvants, dopamine and phenylephrine, on the cutaneous analgesic effect and duration of mexiletine in rats. Methods Nociceptive blockage was evaluated by the
Kesong Zheng +4 more
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Effect of Phenylephrine on Cerebrovascular Regulation: A Translational Perspective [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Phenylephrine is an alpha 1‐adrenergic receptor (α1R) agonist. Evidence indicates activation of α1Rs can initiate both vasoconstrictor and dilator signaling. How phenylephrine affects cerebrovascular regulation remains unclear.
Adam M. S. Luchkanych +13 more
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Drug Design, Development and TherapyJunqin Mao,1,* Kang Lin,2,* Xiang Liu,1 Jie Liu,1 Gang Liang,1 Zhimin Sheng1 1Department of Anesthesiology, Wenling Maternity and Child Health Care Hospital, Taizhou, Zhejiang, People’s Republic of China; 2Department of Anesthesiology, Wenling ...
Mao J +5 more
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Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
, 2014 Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel +6 more
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BMC Anesthesiology, 2022 Background Hypotension that is resistant to phenylephrine is a complication that occurs in anesthetized patients treated with angiotensin converting enzyme (ACE) inhibitors.
Mary E. Schulz +4 more
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The effect of bolus injection of phenylephrine and norepinephrine in preventing hypotension in spinal anesthesia in patients undergoing elective cesarean section: a single-blind clinical trial study [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2023 Introduction: Neuraxial analgesia is the most efficient way to relieve pain during delivery. Hypotension is commonly occurred in cesarean surgery. The vasopressors are used as one of the most important methods of prevention and treatment of hypotension ...
Sepideh Yazdanpanah +4 more
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The effect of the intravenous phenylephrine on the level of spinal anesthesia [PDF]
Korean Journal of Anesthesiology, 2011 BackgroundSpinal anesthesia causes hypotension and bradycardia due to sympathetic nerve block and it is difficult to predict the level of sensory block and the duration of blockade.
Young Hoon Park +4 more
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Frontiers in Pharmacology, 2022 Purpose: The relative potency of norepinephrine and phenylephrine given as boluses to treat hypotension during spinal anesthesia for cesarean delivery has been reported but few data are available for infusions.
Jing Qian +13 more
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Influence of Various Factors on Results on Phenylephrine Test
Oftalʹmologiâ, 2020 Phenylephrine test is one of the main factors determining the possibility of performing superior tarsal muscle resection. However, the influence of various factors on its result remains unexplored.Aim.
V. V. Potyomkin, E. V. Goltsman
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