Results 1 to 10 of about 3,054,079 (160)

Study of the Potential Endocrine-Disrupting Effects of Phenylurea Compounds on Neurohypophysis Cells In Vitro [PDF]

International Journal of Endocrinology, 2019
Homeostatic disruptor agents, and endocrine disruptor compounds (EDC) specifically, can originate from agricultural and industrial chemicals. If they modify the adaptation of living organisms as direct (e.g., by altering hormone regulation, membrane functions) and/or indirect (e.g., cell transformation mechanisms) factors, they are classified as EDC ...
Krisztián Sepp, Zsolt Molnár, Anna M. László, Tünde Alapi, László Tóth, Andrea Serester, Zsuzsanna Valkusz, Márta Gálfi, Marianna Radács   +8 more
semanticscholar   +6 more sources

Substructure-activity relationship studies on antibody recognition for phenylurea compounds using competitive immunoassay and computational chemistry [PDF]

Scientific Reports, 2018
AbstractBased on the structural features of fluometuron, an immunizing hapten was synthesized and conjugated to bovine serum albumin as an immunogen to prepare a polyclonal antibody. However, the resultant antibody indicated cross-reactivity with 6 structurally similar phenylurea herbicides, with binding activities (expressed by IC50 values) ranging ...
Zhang, Fuyuan, Liu, Bing, Liu, Guozhen, Zhang, Yan, Wang, Junping, Wang, Shuo   +5 more
semanticscholar   +4 more sources

Ditopic Receptors Based on Dihomooxacalix[4]arenes Bearing Phenylurea Moieties With Electron-Withdrawing Groups for Anions and Organic Ion Pairs

Frontiers in Chemistry, 2019
Two bidentate dihomooxacalix[4]arene receptors bearing phenylurea moieties substituted with electron-withdrawing groups at the lower rim via a butyl spacer (CF3-Phurea 5b and NO2 Phurea 5c) were obtained in the cone conformation in solution, as shown by ...
Alexandre S. Miranda, Defne Serbetci, P. M. Marcos, J. Ascenso, M. Berberan-Santos, N. Hickey, S. Geremia   +6 more
semanticscholar   +3 more sources

Design, Synthesis and Insecticidal Activity of Novel Phenylurea Derivatives

Molecules, 2015
A series of novel phenylurea derivatives were designed and synthesized according to the method of active groups linkage and the principle of aromatic groups bioisosterism in this study.
Jialong Sun, Yuanming Zhou
semanticscholar   +3 more sources

Novel pyrimidine-piperazine hybrids as potential antimicrobial agents: in-vitro antimicrobial and in-silico studies

Results in Chemistry, 2023
A series of new pyrimidine-piperazine hybrid molecules ware designed and synthesized as possible antimicrobial agents. The synthesized compounds (20 derivatives) were characterized using 1HNMR, 13C NMR, MS and elemental analysis and then the activity of ...
Swathi Rejinthala, Srinivas Endoori, Divya Vemula, Vasundhra Bhandari, T. Mondal   +4 more
doaj   +1 more source

Enhanced Biodegradation of Phenylurea Herbicides by Ochrobactrum anthrophi CD3 Assessment of Its Feasibility in Diuron-Contaminated Soils

International Journal of Environmental Research and Public Health, 2022
The phenylurea herbicides are persistent in soil and water, making necessary the de-velopment of techniques for their removal from the environment. To identify new options in this regard, bacterial strains were isolated from a soil historically managed ...
L. Alba, Morillo Esmeralda, Villaverde Jaime   +2 more
semanticscholar   +1 more source

Contamination Pattern and Risk Assessment of Polar Compounds in Snow Melt: An Integrative Proxy of Road Runoffs

Environmental Science and Technology, 2023
To assess the contamination and potential risk of snow melt with polar compounds, road and background snow was sampled during a melting event at 23 sites at the city of Leipzig and screened for 489 chemicals using liquid chromatography high-resolution ...
L. Maurer, Eric Carmona, Oliver Machate, T. Schulze, M. Krauss, W. Brack   +5 more
semanticscholar   +1 more source

Evaluation of the Binding Properties of A New Phenylurea Appended Carbazole Compound to Pepsin/Trypsin by Computational and Multi-Spectral Analysis

Journal of Fluorescence, 2023
Abstract A novel carbazole compound, named 1-(9-ethyl-9H-carbazol-3-yl)-3-phenylurea (Cpu) was synthesized and its binding properties with protease enzymes (pepsin and trypsin) has been examined by steady-state fluorescence measurements, UV/vis absorption, infrared (FT-IR) and circular dicroism (CD) spectroscopies and also computational methods.
GÖKOĞLU, ELMAS, Taskin-Tok, Tugba, SEFEROĞLU, ZEYNEL, Doyuran, Bensu, Özen, Gülşah, Duyar, Halil   +5 more
openaire   +3 more sources

Rational Design, Synthesis and Cytotoxic Activity of N-(Phenylcarbamoyl)Benzamide on HeLa Cell Lines

Journal of Mathematical and Fundamental Sciences, 2020
Urea derivatives are extensively used in the pharmaceutical industry. However, the unsatisfactory level of their membrane penetration requires further modification of the structures with stronger lipophillic properties. Phenylurea has a phenyl group that
Bambang Tri Purwanto, Siswandono Siswandono, Suko Hardjono, Dian Triwidiandany   +3 more
doaj   +1 more source

Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity

BMC Chemistry, 2022
Background Compounds possessing urea/thiourea moiety have a wide range of biological properties including anticancer activity. On the other hand, taking advantage of the low toxicity and structural diversity of hydrazone derivatives, they are presently ...
Nasrin Nassiri Koopaei, Mehrasa Shademani, Nasrin Shirzad Yazdi, Raheleh Tahmasvand, Mina Dehbid, Mansur Nassiri Koopaei, Homa Azizian, Zahra Mousavi, Ali Almasirad, Mona Salimi   +9 more
doaj   +1 more source