Results 41 to 50 of about 4,825 (166)

Synthesis of 2‐Aryl(alkyl)benzimidazole Hydroxamic Acids as HDAC Inhibitors with Anti‐Angiogenesis Properties

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
2‐Aryl(alkyl)benzimidazole hydroxamic acids (11‐16) are potent and selective HDAC6 inhibitors, with minimal activity against HDAC1/2, and also display anti‐angiogenic and anticancer activities. Compound 13 exhibited a GI50 of 3.9 μM against EPCs and inhibited the growth of HCT‐116, SK‐Hep‐1, and PC‐3 cells with GI50 values of 1.3, 4.2, and 7.5 μM ...
Yi‐Ting Liu, Cheng‐Ta Lai, Shih‐Wei Wang, Shan‐Chi Liu, Yi‐Lin Hwang, Yi‐Chen Tsai, Chi‐Yeh Lee, Yu‐Wei Lai, Juei‐Yu Yen, Po‐Chuan Wang, Hsueh‐Yun Lee   +10 more
wiley   +1 more source

The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments [PDF]

, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Springer Science+Business Media B.V.The partitioning of steroid estrogens in wastewater treatment and receiving waters is likely to ...
Scrimshaw, Mark D., Rachel L. Gomes, Gomes, Rachel L., Scrimshaw, MD, Lester, John N., Lester, JN, John N. Lester, Gomes, RL, Mark D. Scrimshaw, Cartmell, Elise, Elise Cartmell, Cartmell, E   +11 more
core   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

ChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Exogenous Cytokinin 4PU-30 Modulates the Response of Wheat and Einkorn Seedlings to Ultraviolet B Radiation

Plants
Abiotic stress is responsible for a significant reduction in crop plant productivity worldwide. Ultraviolet (UV) radiation is a natural component of sunlight and a permanent environmental stimulus.
Elisaveta Kirova, Irina Moskova, Vasilissa Manova, Yana Koycheva, Zoia Tsekova, Denitsa Borisova, Hristo Nikolov, Ventzeslav Dimitrov, Iskren Sergiev, Konstantina Kocheva   +9 more
doaj   +1 more source

The optimization of crop response to climatic stress through modulation of plant stress response mechanisms. Opportunities for biostimulants and plant hormones to meet climate challenges.

New Phytologist, Volume 249, Issue 1, Page 130-151, January 2026.
Summary This review discusses the use of agronomic management practices to enhance crop stress resilience to climate stress through the modulation of natural plant growth regulatory pathways. The use of biostimulants or plant hormones to improve crop resilience is subject to strict regulatory oversight if changes in the regulation of plant growth are ...
Jing Li, Giulia Forghieri, Danny Geelen, Patrick du Jardin, Patrick H. Brown   +4 more
wiley   +1 more source

Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction

Pharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
ABSTRACT Inhibition of vasocontraction accounts for side effects in treating voiding symptoms in benign prostatic hyperplasia (BPH). We examined the vasoactivity of compounds previously showing inhibition of prostate smooth muscle contraction. Contractions of porcine renal interlobar and coronary arteries were induced by agonists or electric field ...
Guangyang Liu, Sheng Hu, Alexander Tamalunas, Oluwafemi Kale, Yajie Xu, Christian G. Stief, Martin Hennenberg   +6 more
wiley   +1 more source

Biotransformation of phenylurea herbicides by a soil bacterial strain, arthrobacter sp N2 : structure, ecotoxicity and fate of diuron metabolite with soil fungi [PDF]

, 2002
International audienceIn order to assess the influence of the aromatic substitution on the ability of a soil bacterial strain, Arthrobacter sp. N2, to degrade phenylurea herbicides, biotransformation assays were performed in mineral medium with resting ...
Ait-Aissa, Selim, Sancelme, Martine, Veschambre, Henri, Widehem, Pascale, Cuer, Annie, Truffaut, Nicole, Bonnemoy, Frédérique, Tixier, Céline   +7 more
core   +1 more source

Proteome Analysis of the Specific Proteins From Japanese Birch Callus Infected With a Canker‐Rot Fungus Inonotus Obliquus Strain IO‐U1 (NBRC 113406)

Forest Pathology, Volume 55, Issue 6, December 2025.
ABSTRACT The specific proteins from Japanese birch (Betula platyphylla var. japonica plantlet No. 8) callus infected with a canker‐rot fungus Inonotus obliquus strain IO‐U1 (NBRC 113406) at the early infection stage were identified using proteome analysis. The intact, wounded, and infected calli were prepared, and the protein samples obtained at 2 days
Retno Agnestisia, Rei Chino, Ikumi Nezu, Futoshi Ishiguri, Takayuki Tohge, Shinso Yokota   +5 more
wiley   +1 more source

BIOLOGICAL EVALUATION OF 1-(4-(HYDROXY(1-OXO-1,3-DIHYDRO-2H-INDEN-2-YLI-DENE)METHYL)PHENYL)-3-PHENYLUREA DERIVATIVES: ANTICHOLINERGICS AND ANTIEPILEPTIC POTENTIALS [PDF]

, 2019
In this work, a class of phenylurea compounds containing 2-benzoylindan-1-one molecules 3a-3j was designed and synthesized from the reaction of phenylurea-substituted acetophenone compounds with phthalaldehyde molecule under mild action situations in ...
Kocyigit, Umit Muhammet
core  

Multi-residues analysis of pre-emergence herbicides in fluvial sediments : application to the mid-Garonne River [PDF]

, 2007
Contamination of man and ecosystems by pesticides has become a major environmental concern. Whereas many studies exist on contamination from agriculture, the effects of urban sources are usually omitted. Fluvial sediment is a complex matrix of pollutants
Probst, Jean-Luc, Lim, Puy, Pinelli, Eric, Merlina, Georges, Devault, Damien A.   +4 more
core   +1 more source