Results 1 to 10 of about 4,598 (120)

Study of the Potential Endocrine-Disrupting Effects of Phenylurea Compounds on Neurohypophysis Cells In Vitro [PDF]

International Journal of Endocrinology, 2019
Homeostatic disruptor agents, and endocrine disruptor compounds (EDC) specifically, can originate from agricultural and industrial chemicals. If they modify the adaptation of living organisms as direct (e.g., by altering hormone regulation, membrane ...
Krisztián Sepp, Zsolt Molnár, Anna M. László, Tünde Alapi, László Tóth, Andrea Serester, Zsuzsanna Valkusz, Márta Gálfi, Marianna Radács   +8 more
doaj   +6 more sources

Current-use and legacy pesticides in canal waters of Chiang Mai, Thailand, during longan flowering and fruit set: occurrence and ecological and human health risk assessment [PDF]

Scientific Reports
This study investigated the occurrence of pesticides, their ecological risks, and potential human health implications in irrigation–drainage canals of Chiang Mai’s longan orchards during two phenological stages: flowering and easrly fruit development. In
Patchimaporn Udomkun, Thidarat Rupngam, Margaret Graham, Thirasant Boonupara, Puangrat Kaewlom   +4 more
doaj   +2 more sources

Design, Synthesis and Insecticidal Activity of Novel Phenylurea Derivatives

Molecules, 2015
A series of novel phenylurea derivatives were designed and synthesized according to the method of active groups linkage and the principle of aromatic groups bioisosterism in this study.
Jialong Sun, Yuanming Zhou
doaj   +3 more sources

Design, Synthesis, Molecular Docking, and Anticancer Activity of Chalcone Derivatives as VEGFR-2 Inhibitors [PDF]

Molecules
A series of 4-phenylurea chalcones (2a–2s) as VEGFR-2 inhibitors has been designed, synthesized, and evaluated for in vitro cytotoxic activity against K562, SiHa, and B16 cancer cells.
Mingjun Yu, Xin Zhang, Hui Zhu, Xiaoqian Zhang   +3 more
doaj   +2 more sources

Novel pyrimidine-piperazine hybrids as potential antimicrobial agents: in-vitro antimicrobial and in-silico studies

Results in Chemistry, 2023
A series of new pyrimidine-piperazine hybrid molecules ware designed and synthesized as possible antimicrobial agents. The synthesized compounds (20 derivatives) were characterized using 1HNMR, 13C NMR, MS and elemental analysis and then the activity of ...
Swathi Rejinthala, Srinivas Endoori, Divya Vemula, Vasundhra Bhandari, T. Mondal   +4 more
doaj   +1 more source

Rational Design, Synthesis and Cytotoxic Activity of N-(Phenylcarbamoyl)Benzamide on HeLa Cell Lines

Journal of Mathematical and Fundamental Sciences, 2020
Urea derivatives are extensively used in the pharmaceutical industry. However, the unsatisfactory level of their membrane penetration requires further modification of the structures with stronger lipophillic properties. Phenylurea has a phenyl group that
Bambang Tri Purwanto, Siswandono Siswandono, Suko Hardjono, Dian Triwidiandany   +3 more
doaj   +1 more source

Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity

BMC Chemistry, 2022
Background Compounds possessing urea/thiourea moiety have a wide range of biological properties including anticancer activity. On the other hand, taking advantage of the low toxicity and structural diversity of hydrazone derivatives, they are presently ...
Nasrin Nassiri Koopaei, Mehrasa Shademani, Nasrin Shirzad Yazdi, Raheleh Tahmasvand, Mina Dehbid, Mansur Nassiri Koopaei, Homa Azizian, Zahra Mousavi, Ali Almasirad, Mona Salimi   +9 more
doaj   +1 more source

Transcriptomic and Metabolomic Studies Reveal Mechanisms of Effects of CPPU-Mediated Fruit-Setting on Attenuating Volatile Attributes of Melon Fruit

Agronomy, 2021
N1-(2-chloro-4-pyridyl)-N3-phenylurea (CPPU), a synthetic cytokinin-active compound, is widely applied to induce parthenocarpic fruit set and enhance melon fruit enlargement (Cucumis melo L.).
Jufen Li, Tao Lin, Dandan Ren, Tan Wang, Ying Tang, Yiwen Wang, Ling Xu, Pinkuan Zhu, Guobin Ma   +8 more
doaj   +1 more source

Response of salt stressed barley seedlings to phenylurea

Plant, Soil and Environment, 2003
The effect of phenylurea with reported cytokinin-like activities on seed germination, seedling growth, activities of antioxidant enzymes, polyphenol, peroxidase, indoleacetic acid oxidase, and total phenolic compounds, flavonoids was investigated in ...
R.M. Ali, H.M. Abbas
doaj   +1 more source

Development of Simultaneous Determination Method of Pesticide High Toxic Metabolite 3,4-Dichloroaniline and 3,5 Dichloroaniline in Chives Using HPLC-MS/MS

Foods, 2023
3,4-dichloroaniline (3,4-DCA) and 3,5-dichloroaniline (3,5-DCA) are, respectively, the primary metabolites deriving from the breakdown of phenylurea herbicides and dicarboximide fungicides in both soils and plants, whose residues in vegetable products ...
Yibo Dong, Xiaolong Yao, Wanping Zhang, Xiaomao Wu   +3 more
doaj   +1 more source