Design, Synthesis, Molecular Docking, and Anticancer Activity of Chalcone Derivatives as VEGFR-2 Inhibitors [PDF]
A series of 4-phenylurea chalcones (2a–2s) as VEGFR-2 inhibitors has been designed, synthesized, and evaluated for in vitro cytotoxic activity against K562, SiHa, and B16 cancer cells.
Mingjun Yu +3 more
doaj +2 more sources
N1-(2-chloro-4-pyridyl)-N3-phenylurea (CPPU), a synthetic cytokinin-active compound, is widely applied to induce parthenocarpic fruit set and enhance melon fruit enlargement (Cucumis melo L.).
Jufen Li +8 more
doaj +1 more source
Response of salt stressed barley seedlings to phenylurea
The effect of phenylurea with reported cytokinin-like activities on seed germination, seedling growth, activities of antioxidant enzymes, polyphenol, peroxidase, indoleacetic acid oxidase, and total phenolic compounds, flavonoids was investigated in ...
R.M. Ali, H.M. Abbas
doaj +1 more source
3,4-dichloroaniline (3,4-DCA) and 3,5-dichloroaniline (3,5-DCA) are, respectively, the primary metabolites deriving from the breakdown of phenylurea herbicides and dicarboximide fungicides in both soils and plants, whose residues in vegetable products ...
Yibo Dong +3 more
doaj +1 more source
Emerging Investigators Series: Pyrolysis Removes Common Microconstituents Triclocarban, Triclosan, and Nonylphenol from Biosolids [PDF]
Reusing biosolids is vital for the sustainability of wastewater management. Pyrolysis is an anoxic thermal degradation process that can be used to convert biosolids into energy rich py-gas and py-oil, and a beneficial soil amendment, biochar.
McNamara, Patrick J. +4 more
core +2 more sources
Targeting kinases with anilinopyrimidines: Discovery of N-phenyl-N'-[4-(pyrimidin-4-ylamino)phenyl]urea derivatives as selective inhibitors of class III receptor tyrosine kinase subfamily [PDF]
Kinase inhibitors are attractive drugs/drug candidates for the treatment of cancer. The most recent literature has highlighted the importance of multi target kinase inhibitors, although a correct balance between specificity and non-specificity is ...
Chilin, Adriana +5 more
core +2 more sources
Phenylurea groups were introduced into the frame of traditional cyanoacrylate and a series of N-(3-benzylamino-2-cyano-3-methylthioacrylyl)-N'-(substituted phenyl)ureas were synthesized. All compounds are new and their structures were confirmed by 1H NMR,
D.M. Wei +4 more
doaj +1 more source
Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates [PDF]
Fentanyl is a powerful opiate analgesic typically used for the treatment of severe and chronic pain, but its prescription is strongly limited by the well-documented side-effects.
Benyhe, Sa ́ndor +18 more
core +1 more source
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea [PDF]
Tuberculosis is a major threat for mankind and the emergence of resistance strain of Mycobacterium tuberculosis (Mtb) against first line antibiotics makes it lethal for human civilization.
Charan Raja, Mamilla R. +10 more
core +1 more source
On the Thermal Dissociation of Organic Compounds. XII. The Effects of the Substituents on the Thermal Dissociation of Substituted Phenylureas [PDF]
Abstract Eleven new ureas of the type, 1,1-diethyl-3-arylureas and 1-pentyl-3-arylureas were synthesized. The rate constants and ρ values of thermal dissociation of these ureas in fatty acids were determined. In 1,1-diethyl-3-arylureas, the ρ value of the dissociation reaction at 95°C.
Shoichiro Ozaki, Tsutomu Nagoya
openaire +1 more source

