Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists [PDF]
β-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β1 ...
Arch J. R. S. +52 more
core +2 more sources
A DFT study of the chemical bonding properties, aromaticity indexes and molecular docking study of some phenylureas herbicides [PDF]
Herbicides have imposed disastrous consequences towards the environment and human health. This practice urges scientists to investigate the physical, chemical and biological properties of these substances to avoid the use of the most harmful pesticides ...
Laib Souhila +2 more
doaj +1 more source
Effects of organic herbicides on phototrophic microbial communities in freshwater ecosystems [PDF]
Over the past 15 years, significant research efforts have been channelled into assessing the effects of organic herbicides on freshwater phototrophic microbial communities. The results of this research are reviewed herein.
Bouchez, Agnes, Montuelle, B., Pesce, S.
core +4 more sources
Identification of the functional binding pocket for compounds targeting small-conductance Ca²⁺-activated potassium channels. [PDF]
Small- and intermediate-conductance Ca(2+)-activated potassium channels, activated by Ca(2+)-bound calmodulin, have an important role in regulating membrane excitability. These channels are also linked to clinical abnormalities.
Armen, Roger S +4 more
core +2 more sources
Occurrences of Tire Rubber-Derived Contaminants in Cold-Climate Urban Runoff
Recent findings that 2-anilo-5-[(4-methylpentan-2yl)amino]cyclohexa-2,5-diene-1,4-dione (6PPD-quinone), the transformation product of a common tire rubber antioxidant, is acutely toxic in stormwater-impacted streams has highlighted the need for a better ...
J. Challis +6 more
semanticscholar +1 more source
Adsorption of 3-chloroaniline on potato skin in aqueous solution [PDF]
The adsorption behaviour of aromatic amine 3-chloroaniline (3-CA) from aqueous solution on fresh potato skin was investigated. A series of batch experiments were conducted under different experimental conditions of contact time, 3-chloroaniline ...
Duncan, H.J. +2 more
core +3 more sources
Fate and occurrence of alkylphenolic compounds in sewage sludges determined by liquid chromatography tandem mass spectrometry [PDF]
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2009 Taylor & Francis.An analytical method has been developed and applied to determine the concentrations of the nonionic alkylphenol ...
A. Boobis +14 more
core +1 more source
Forchlorfenuron-mimicking haptens: From immunogen design to antibody characterization by hierarchical clustering analysis [PDF]
To obtain highly-specific and selective forchlorfenuron binders, a collection of functionalized derivatives with different spacer arm locations and lengths was prepared.
Abad Fuentes, Antonio +4 more
core +2 more sources
Synergistic Degradation of Linuron by a Bacterial Consortium and Isolation of a Single Linuron-Degrading Variovorax Strain [PDF]
The bacterial community composition of a linuron-degrading enrichment culture and the role of the individual strains in linuron degradation have been determined by a combination of methods, such as denaturing gradient gel electrophoresis of the total 16S
Berteloot, Ellen +9 more
core +3 more sources
Abiotic stress is responsible for a significant reduction in crop plant productivity worldwide. Ultraviolet (UV) radiation is a natural component of sunlight and a permanent environmental stimulus.
Elisaveta Kirova +9 more
doaj +1 more source

