Results 121 to 130 of about 45,385 (273)
The Milbank Quarterly, EarlyView.Policy Points The original purpose of the 340B program was to exempt Public Health Service Act funded clinics and state and local public hospitals from the inflationary best‐price component of the recently enacted Medicaid drug rebate program. The secondary purpose was to reduce drug prices for these clinics and hospitals in order to preserve and ...
SAYEH NIKPAY +2 more
wiley +1 more source
ClinicoEconomics and Outcomes Research, 2010 Rashid Kazerooni1, Mark Bounthavong1,21Pharmacoeconomics/Formulary Management, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA; 2UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA, USAObjective: There has been ...
Rashid Kazerooni, Mark Bounthavong
doaj
Current Medical IssuesBackground: Phenytoin is a widely used, cost-effective anticonvulsant with a narrow therapeutic range, requiring close monitoring to avoid toxicity. Our aim was to investigate phenytoin toxicity in an emergency department setting, focusing on clinical ...
Nejah F. Ellouze +4 more
doaj +1 more source
CYP2C9 polymorphisms in epilepsy: influence on phenytoin treatment
, 2018 Carlos Eduardo Silvado,1 Vera Cristina Terra,1 Carlos Alexandre Twardowschy2 1Comprehensive Epilepsy Program, Hospital de Clinicas, Federal University of Parana (UFPR), Curitiba, Brazil; 2Department of Neurology, Catholic University of Parana (PUCPR ...
Terra VC, Twardowschy CA, Silvado CE
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Phenytoin Prophylaxis in Posttraumatic Head Injury
, 1996 Objective: To identify the effectiveness of prophylactic phenytoin in preventing posttraumatic epilepsy. Design: Retrospective cohort study. Setting: Urban tertiary-care hospital and trauma center.
Stephen O Ohimor, Robert E Falcone
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Journal of Forensic Sciences, EarlyView.Abstract Diffuse cranial vault hyperostosis is an uncommon finding and may present a diagnostic challenge in clinical and forensic practice. We report the case of a 53‐year‐old woman with a long‐standing history of epilepsy treated with phenytoin and sodium valproate who collapsed at home suddenly and died despite resuscitative efforts.
Maria Piagkou +7 more
wiley +1 more source
Phenytoin-bupropion interaction: effect on plasma phenytoin concentration in the rat
, 1990 The effect of coadministration of bupropion (50 mg kg−1, p.o.) on the disposition profile of phenytoin has been studied in the rat. Plasma phenytoin concentration was measured serially for 10 h by HPLC.
A Tekle, Khalil I Al-Khamis
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Allergy, EarlyView.ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud +14 more
wiley +1 more source
F1000ResearchBackground Phenytoin is an anticonvulsant medication that is effective in treating various seizure disorders. It is mostly metabolized by the liver, which increases the risk of PHT-induced hepatotoxicity. Aims This study aimed to assess the effectiveness
Fadhaa Abdulameer Ghafil +5 more
doaj +1 more source