Epilepsia Open, Volume 10, Issue 6, Page 1774-1782, December 2025.Abstract Objective Epilepsy affects approximately 70 million people worldwide, with 80% living in low‐ and middle‐income countries (LMICs), where many people with epilepsy (PWE) go undiagnosed or untreated. Over the last few decades, many efforts have been made worldwide to reduce the treatment gap (TG) in LMICs.
Alessandra Nicoletti +13 more
wiley +1 more source
Fosphenytoin may be effective in shortening the half-life of lamotrigine in case of overdose: a case report. [PDF]
J Med Case RepSato J +8 more
europepmc +1 more source
Detection of autoantibodies against thyroglobulin, thyroid microsomes, and other soluble antigens with a rational and economical immunoblotting microtechnique [PDF]
, 1985 Berndt, H. +5 more
core +1 more source
Intralitter Variability Influences the Developmental Impact of Valproic Acid Exposure in CD‐1 Mice
Journal of Applied Toxicology, Volume 45, Issue 12, Page 2624-2640, December 2025.ABSTRACT Valproic acid (VPA) is an antiepileptic and mood‐stabilizing drug that causes teratogenic effects, including neural tube defects (NTDs), when taken during pregnancy. Although animal models are widely used to study VPA teratogenicity, most rely on litter means, which overlook variability within the litter.
Lauren T. L. Brown +3 more
wiley +1 more source
Post-traumatic epilepsy: bridging pathogenesis, diagnosis, and pharmacotherapeutic strategies. [PDF]
Front PharmacolYang X, Chen S, Wang H, Sun T, Wu K.
europepmc +1 more source
Saliva as a TDM Matrix and Its Application in the Model‐Informed Precision Dosing
The Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1650-1660, December 2025.Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu +9 more
wiley +1 more source
Role of different anti-seizure medications on carotid intima-media thickness: A systematic review and meta-analysis. [PDF]
Medicine (Baltimore)Davari A +7 more
europepmc +1 more source
Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy [PDF]
, 1984 Berlit, Peter +3 more
core
Evaluating the risk of osteopenia-related adverse events with antiepileptic drugs: a pharmacovigilance study based on the FAERS database. [PDF]
Front PharmacolYang N +6 more
europepmc +1 more source