Results 21 to 30 of about 93,963 (358)

Phenytoin toxicity secondary to friend's advice!!

open access: diamondAnnals of Indian Psychiatry, 2019
It is very common that antiepileptic prescription in substance induced seizure, however Phenytoin abuse is very rare. We report a case of 25 year old man with a known diagnosis of polysubstance abuse.
Jisha Myalil Lucca, Kishore M, Shruthi S
doaj   +2 more sources

Phenytoin induced Chorea: commonly used antiepileptic drug causing a rare movement disorder [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2020
Background: Phenytoin, a commonly prescribed antiepileptic drug, causes side effects like ataxia, tremor, hirsutism, gum hyperplasia, insomnia, confusion, headache and vertigo when used for longer duration.
Rambhupal NAGIREDDY   +3 more
doaj   +1 more source

Phenytoin as seizure prophylaxis in hematopoietic stem cell transplantation with busulfan conditioning

open access: yesFrontiers in Neurology, 2022
BackgroundPhenytoin is widely used as primary seizure prophylaxis in hematopoietic stem cell transplantation in patients undergoing myeloablative conditioning with busulfan. Because of the negative side effects of phenytoin, we abandoned phenytoin use in
R. S. Germeraad   +4 more
doaj   +1 more source

Effect of Topical Phenytoin in Treatment of Corneal Epithelial Defect in Rabbits [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2018
Re-epithelialization of corneal epithelium is a major problem in delayed corneal wound healing. Phenytoin has been used topically for different type of cutaneous wounds and ulcers.
Masoomeh Eghtedari   +2 more
doaj   +3 more sources

The role of heat-not-burn, snus and other nicotine-containing products as interventions for epileptic patients who take phenytoin and smoke cigarettes

open access: yesToxicology Reports, 2022
Background: Cigarette smoke increases the metabolism of phenytoin, a widely used anti-epileptic agent, by inducing cytochrome P450 enzymes in the liver. Therefore, cigarette smoke may reduce the clinical effect of phenytoin.
P.N. Valodia
doaj   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA‐B Genotypes and Phenytoin Dosing: 2020 Update

open access: yesClinical pharmacology and therapy, 2020
Phenytoin is an antiepileptic drug with a narrow therapeutic index and large interpatient pharmacokinetic variability, partly due to genetic variation in CYP2C9.
J. Karnes   +14 more
semanticscholar   +1 more source

Does long‐term phenytoin have a place in Dravet syndrome?

open access: yesAnnals of Clinical and Translational Neurology, 2022
Anti‐seizure medications that block sodium channels are generally considered contraindicated in Dravet syndrome. There is, however, considerable debate about the sodium‐channel blocker phenytoin, which is often used for status epilepticus, a frequent ...
George A. Zographos   +2 more
doaj   +1 more source

Restoration of Germinal Epithelium with Usage of Antioxidant Oils in Phenytoin Induced Testicular Toxicity: A Comparative Study in Rats

open access: yesJournal of Bahria University Medical and Dental College, 2023
Objective: To evaluate antioxidant effect of Virgin Coconut Oil (VCO) and Corn Oil (CO) on germinal thickness (GT) in rats induced with phenytoin toxicity. Study design and setting: An Experimental Longitudinal study was done at AL-Tibri Medical College
Khalique-ur- Rehman   +5 more
doaj   +1 more source

Sertraline and Phenytoin Drug Interaction in a Geriatric Patient [PDF]

open access: yes, 2017
This report presents the case of a 78-year-old man residing in a nursing home who presented with a 2-month history of increasing lethargy and confusion. These symptoms coincided with the initiation of sertraline in the patient.
Caprio, Thomas V.   +4 more
core   +2 more sources

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