Results 11 to 20 of about 64,482 (277)
Sertraline and Phenytoin Drug Interaction in a Geriatric Patient [PDF]
, 2017 This report presents the case of a 78-year-old man residing in a nursing home who presented with a 2-month history of increasing lethargy and confusion. These symptoms coincided with the initiation of sertraline in the patient.
Caprio, Thomas V. +4 more
core +2 more sources
Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]
, 1983 Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
E Perucca +15 more
core +1 more source
Impaired biotin status in anticonvulsant therapy [PDF]
, 1982 In 264 epileptics undergoing long-term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher ...
Bonjour +7 more
core +1 more source
Indian Journal of Anaesthesia, 2017 Background and Aims: Patients with intracranial tumour are usually on anticonvulsants. Patients on phenytoin therapy demonstrate rapid metabolism of nondepolarising muscle relaxants secondary to enzyme induction.
Veena Sheshadri +3 more
doaj +1 more source
Phenytoin Toxicity with High Dose, Concomitant Ascorbic Acid Dosing
INNOVATIONS in Pharmacy, 2022 High dose ascorbic acid may increase risk of phenytoin toxicity. This case report demonstrates high phenytoin levels resulting in adverse drug reactions subsequent to dosing concomitantly with high dose vitamin C, or ascorbic acid (AA), as a precaution ...
Michael J. Schuh +2 more
doaj +1 more source
Anticonvulsant Effect of Nebivolol alone and in Combination with Phenytoin against Maximal Electroshock-Induced Seizures in Mice [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Phenytoin is widely used in treatment of generalised tonic clonic seizures but its adverse effects make its usage limited. Hence forth, there is a need for newer antiepileptics. Studies have shown antiepileptic property for nebivolol in
Anuranjani Dhamodharan +2 more
doaj +1 more source
CYP2C9 polymorphisms are associated with phenytoin toxicity in South-Indian epileptic patients
Journal of Dr. NTR University of Health Sciences, 2020 Background and Aims: The contribution of CYP2C9 in phenytoin metabolism is generally modest, but it increases with increasing serum phenytoin concentration.
Rakesh Reddy Reddigari +4 more
doaj +1 more source
Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway
Regenerative Therapy, 2023 Background: We mainly studied the mechanism by which phenytoin promotes osteogenic differentiation of human jawbone marrow stem cells. Methods: Bone marrow stem cells were extracted from jaw bone tissue debris obtained from 5 subjects undergoing implant ...
Zeliang Zhang +3 more
doaj +1 more source
Journal of Pain Research, 2022 David J Kopsky,1,2 Jan M Keppel Hesselink,1 Alan L Russell,3 Alexander FJE Vrancken2 1Institute for Neuropathic Pain, Amsterdam, the Netherlands; 2Department of Neurology, Brain Centre University Medical Center Utrecht, Utrecht University, Utrecht, the ...
Kopsky DJ +3 more
doaj
Acute Phenytoin Intoxication: Causes, Symptoms, Misdiagnoses, and Outcomes
Kaohsiung Journal of Medical Sciences, 2004 Phenytoin is a commonly prescribed antiepileptic drug. Due to its saturation (zero-order) pharmacokinetics, phenytoin carries a special risk of dose-related toxicity that is an important issue in emergency medicine.
Wen-Juh Hwang, Jing-Jane Tsai
doaj +1 more source