Results 11 to 20 of about 36,105 (235)
Anticonvulsant Effect of Nebivolol alone and in Combination with Phenytoin against Maximal Electroshock-Induced Seizures in Mice [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Phenytoin is widely used in treatment of generalised tonic clonic seizures but its adverse effects make its usage limited. Hence forth, there is a need for newer antiepileptics. Studies have shown antiepileptic property for nebivolol in
Anuranjani Dhamodharan +2 more
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Indian Journal of Anaesthesia, 2017 Background and Aims: Patients with intracranial tumour are usually on anticonvulsants. Patients on phenytoin therapy demonstrate rapid metabolism of nondepolarising muscle relaxants secondary to enzyme induction.
Veena Sheshadri +3 more
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CYP2C9 polymorphisms are associated with phenytoin toxicity in South-Indian epileptic patients
Journal of Dr. NTR University of Health Sciences, 2020 Background and Aims: The contribution of CYP2C9 in phenytoin metabolism is generally modest, but it increases with increasing serum phenytoin concentration.
Rakesh Reddy Reddigari +4 more
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Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway
Regenerative Therapy, 2023 Background: We mainly studied the mechanism by which phenytoin promotes osteogenic differentiation of human jawbone marrow stem cells. Methods: Bone marrow stem cells were extracted from jaw bone tissue debris obtained from 5 subjects undergoing implant ...
Zeliang Zhang +3 more
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The Possible Protective Role of Selenium Against Long-Term Phenytoin Administration Effects on Cerebellar Cortex of Adult Male Albino Rats: Histological and Immunohistochemical Study [PDF]
The Egyptian Journal of Histology, 2020 Background: Phenytoin is a commonly prescribed antiepileptic drug. Chronic phenytoin treatment has been documented to be associated with cerebellar degeneration.
Enas Bekheet
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Journal of Pain Research, 2022 David J Kopsky,1,2 Jan M Keppel Hesselink,1 Alan L Russell,3 Alexander FJE Vrancken2 1Institute for Neuropathic Pain, Amsterdam, the Netherlands; 2Department of Neurology, Brain Centre University Medical Center Utrecht, Utrecht University, Utrecht, the ...
Kopsky DJ +3 more
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Acute Phenytoin Intoxication: Causes, Symptoms, Misdiagnoses, and Outcomes
Kaohsiung Journal of Medical Sciences, 2004 Phenytoin is a commonly prescribed antiepileptic drug. Due to its saturation (zero-order) pharmacokinetics, phenytoin carries a special risk of dose-related toxicity that is an important issue in emergency medicine.
Wen-Juh Hwang, Jing-Jane Tsai
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Effect of Pioglitazone on Plasma Levels of Phenytoin in Rats [PDF]
Journal of Cardio-Thoracic Medicine, 2013 Introduction: Interaction between drugs represents a major clinical concern for health care professionals and their patients. Patients affected by both type 2 diabetes and epilepsy may be prescribed pioglitazone and an anti-epileptic drug such as ...
Abolghasem Jouyban +3 more
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Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report
Case Reports in Cardiology, 2014 We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder.
Ravi K. Thimmisetty +2 more
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Indian Journal of Neurosurgery, 2019 Introduction Antiepileptic drug (AED) therapy has been used prophylactically in various centers in patients with chronic subdural hematoma (CSDH) after surgical evacuation, although the benefit is unclear.
Amit Bahadur Pradhanang +3 more
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