Results 21 to 30 of about 45,385 (273)

Phenytoin and carbamazepine in trigeminal neuralgia: marketing-based versus evidence-based treatment [PDF]

open access: yes, 2017
Jan M Keppel Hesselink,1 Michael E Schatman2,31Institute for Neuropathic Pain, Bosch en Duin, the Netherlands; 2Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA; 3Boston Pain Care, Waltham, MA ...
Schatman ME   +3 more
core   +1 more source

Acute Phenytoin Intoxication: Causes, Symptoms, Misdiagnoses, and Outcomes

open access: yesKaohsiung Journal of Medical Sciences, 2004
Phenytoin is a commonly prescribed antiepileptic drug. Due to its saturation (zero-order) pharmacokinetics, phenytoin carries a special risk of dose-related toxicity that is an important issue in emergency medicine.
Wen-Juh Hwang, Jing-Jane Tsai
doaj   +1 more source

Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]

open access: yes, 1983
Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
Rascher, W.   +5 more
core   +1 more source

No Detectable Phenytoin Plasma Levels After Topical Phenytoin Cream Application in Chronic Pain: Inferences for Mechanisms of Action

open access: yesJournal of Pain Research, 2022
David J Kopsky,1,2 Jan M Keppel Hesselink,1 Alan L Russell,3 Alexander FJE Vrancken2 1Institute for Neuropathic Pain, Amsterdam, the Netherlands; 2Department of Neurology, Brain Centre University Medical Center Utrecht, Utrecht University, Utrecht, the ...
Kopsky DJ   +3 more
doaj  

Mechanistic Insights on the Mechanosynthesis of Phenytoin, a WHO Essential Medicine [PDF]

open access: yes, 2021
In recent years, mechanochemistry has enriched the toolbox of synthetic chemists, enabling faster and more sustainable access to new materials and existing products, including active pharmaceutical ingredients (APIs).
Francesco, Puccetti   +6 more
core   +2 more sources

Effect of Pioglitazone on Plasma Levels of Phenytoin in Rats [PDF]

open access: yesJournal of Cardio-Thoracic Medicine, 2013
Introduction: Interaction between drugs represents a major clinical concern for health care professionals and their patients. Patients affected by both type 2 diabetes and epilepsy may be prescribed pioglitazone and an anti-epileptic drug such as ...
Abolghasem Jouyban   +3 more
doaj   +2 more sources

Phenytoin-sodium induced gingival overgrowth [PDF]

open access: yes, 1984
Magister Chirurgiae Dentium (MChD)Epilepsy is a fairly common condition and the anti-convulsant drug, phenytoin sodium, has been used in its treatment for over 40 years.
Radomsky, Jack Bernard
core   +1 more source

Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report

open access: yesCase Reports in Cardiology, 2014
We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder.
Ravi K. Thimmisetty   +2 more
doaj   +1 more source

Prophylactic Use of Antiepileptic Drug (Phenytoin) in Preventing Early Postoperative Seizure in Patients with Chronic Subdural Hematoma: A Randomized Control Trial

open access: yesIndian Journal of Neurosurgery, 2019
Introduction Antiepileptic drug (AED) therapy has been used prophylactically in various centers in patients with chronic subdural hematoma (CSDH) after surgical evacuation, although the benefit is unclear.
Amit Bahadur Pradhanang   +3 more
doaj   +1 more source

Dose adjustment of phenytoin for comedication in Japanese patients with epilepsy [PDF]

open access: yes, 2013
香川大学Kagawa University博士(医学)Abstract This study sought a suitable physiological parameter related to daily phenytoin (PHT) dose (D) providing a steady-state serum concentration (Ct) and analyzed the influences of coadministered antiepileptic drugs on Ct ...
フクオカ, ノリヤス   +2 more
core   +1 more source

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