Results 21 to 30 of about 46,241 (267)
Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]
Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
Rascher, W. +5 more
core +1 more source
Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway
Background: We mainly studied the mechanism by which phenytoin promotes osteogenic differentiation of human jawbone marrow stem cells. Methods: Bone marrow stem cells were extracted from jaw bone tissue debris obtained from 5 subjects undergoing implant ...
Zeliang Zhang +3 more
doaj +1 more source
Acute Phenytoin Intoxication: Causes, Symptoms, Misdiagnoses, and Outcomes
Phenytoin is a commonly prescribed antiepileptic drug. Due to its saturation (zero-order) pharmacokinetics, phenytoin carries a special risk of dose-related toxicity that is an important issue in emergency medicine.
Wen-Juh Hwang, Jing-Jane Tsai
doaj +1 more source
David J Kopsky,1,2 Jan M Keppel Hesselink,1 Alan L Russell,3 Alexander FJE Vrancken2 1Institute for Neuropathic Pain, Amsterdam, the Netherlands; 2Department of Neurology, Brain Centre University Medical Center Utrecht, Utrecht University, Utrecht, the ...
Kopsky DJ +3 more
doaj
Effect of Pioglitazone on Plasma Levels of Phenytoin in Rats [PDF]
Introduction: Interaction between drugs represents a major clinical concern for health care professionals and their patients. Patients affected by both type 2 diabetes and epilepsy may be prescribed pioglitazone and an anti-epileptic drug such as ...
Abolghasem Jouyban +3 more
doaj +2 more sources
Contributions to an improved phenytoin monitoring and dosing in hospitalized patients [PDF]
Phenytoin (PHT) is one of the mostly used and well established anticonvulsants for the treatment of epilepsy and a standard in the antiepileptic prophylaxis in adults with severe traumatic brain injuries before and after neurosurgical intervention. Its
Tobler-Giger, Andrea
core +1 more source
Introduction Antiepileptic drug (AED) therapy has been used prophylactically in various centers in patients with chronic subdural hematoma (CSDH) after surgical evacuation, although the benefit is unclear.
Amit Bahadur Pradhanang +3 more
doaj +1 more source
Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report
We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder.
Ravi K. Thimmisetty +2 more
doaj +1 more source
Phenytoin Induced Cerebral Atrophy: A Case Report [PDF]
Phenytoin is the most common drug prescribed in patient diagnosed with seizure. Cerebral atrophy is an observed complication in phenytoin exposed patients.
Linggi, Celeste +4 more
core +1 more source
Objective: Phenytoin is an antiepileptic drug used widely for prophylaxis and treatment of seizure after neurotrauma. Phenytoin has a complex pharmacokinetics and monitoring of its serum concentrations is recommended during treatment.
Kourosh Sadeghi +10 more
doaj +1 more source

