Results 21 to 30 of about 46,241 (267)

Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]

open access: yes, 1983
Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
Rascher, W.   +5 more
core   +1 more source

Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway

open access: yesRegenerative Therapy, 2023
Background: We mainly studied the mechanism by which phenytoin promotes osteogenic differentiation of human jawbone marrow stem cells. Methods: Bone marrow stem cells were extracted from jaw bone tissue debris obtained from 5 subjects undergoing implant ...
Zeliang Zhang   +3 more
doaj   +1 more source

Acute Phenytoin Intoxication: Causes, Symptoms, Misdiagnoses, and Outcomes

open access: yesKaohsiung Journal of Medical Sciences, 2004
Phenytoin is a commonly prescribed antiepileptic drug. Due to its saturation (zero-order) pharmacokinetics, phenytoin carries a special risk of dose-related toxicity that is an important issue in emergency medicine.
Wen-Juh Hwang, Jing-Jane Tsai
doaj   +1 more source

No Detectable Phenytoin Plasma Levels After Topical Phenytoin Cream Application in Chronic Pain: Inferences for Mechanisms of Action

open access: yesJournal of Pain Research, 2022
David J Kopsky,1,2 Jan M Keppel Hesselink,1 Alan L Russell,3 Alexander FJE Vrancken2 1Institute for Neuropathic Pain, Amsterdam, the Netherlands; 2Department of Neurology, Brain Centre University Medical Center Utrecht, Utrecht University, Utrecht, the ...
Kopsky DJ   +3 more
doaj  

Effect of Pioglitazone on Plasma Levels of Phenytoin in Rats [PDF]

open access: yesJournal of Cardio-Thoracic Medicine, 2013
Introduction: Interaction between drugs represents a major clinical concern for health care professionals and their patients. Patients affected by both type 2 diabetes and epilepsy may be prescribed pioglitazone and an anti-epileptic drug such as ...
Abolghasem Jouyban   +3 more
doaj   +2 more sources

Contributions to an improved phenytoin monitoring and dosing in hospitalized patients [PDF]

open access: yes, 2016
Phenytoin (PHT) is one of the mostly used and well established anticonvulsants for the treatment of epilepsy and a standard in the antiepileptic prophylaxis in adults with severe traumatic brain injuries before and after neurosurgical intervention. Its
Tobler-Giger, Andrea
core   +1 more source

Prophylactic Use of Antiepileptic Drug (Phenytoin) in Preventing Early Postoperative Seizure in Patients with Chronic Subdural Hematoma: A Randomized Control Trial

open access: yesIndian Journal of Neurosurgery, 2019
Introduction Antiepileptic drug (AED) therapy has been used prophylactically in various centers in patients with chronic subdural hematoma (CSDH) after surgical evacuation, although the benefit is unclear.
Amit Bahadur Pradhanang   +3 more
doaj   +1 more source

Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report

open access: yesCase Reports in Cardiology, 2014
We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder.
Ravi K. Thimmisetty   +2 more
doaj   +1 more source

Phenytoin Induced Cerebral Atrophy: A Case Report [PDF]

open access: yes, 2022
Phenytoin is the most common drug prescribed in patient diagnosed with seizure. Cerebral atrophy is an observed complication in phenytoin exposed patients.
Linggi, Celeste   +4 more
core   +1 more source

Total Phenytoin concentration is not well correlated with active free drug in critically-ill head trauma patients

open access: yesJournal of Research in Pharmacy Practice, 2013
Objective: Phenytoin is an antiepileptic drug used widely for prophylaxis and treatment of seizure after neurotrauma. Phenytoin has a complex pharmacokinetics and monitoring of its serum concentrations is recommended during treatment.
Kourosh Sadeghi   +10 more
doaj   +1 more source

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