Results 71 to 80 of about 621,544 (210)

Carnitine deficiency presenting with encephalopathy and hyperammonemia in a patient receiving chronic enteral tube feeding: a case report

Journal of Medical Case Reports, 2012
Introduction Carnitine is an essential cofactor in mitochondrial fatty acid oxidation. Carnitine deficiency results in accumulation of non-oxidized fatty acyl-coenzyme A molecules, and this inhibits intra-mitochondrial degradation of ammonia ...
Ling Peter, Lee Douglas J, Yoshida Eric M, Sirrs Sandra   +3 more
doaj   +1 more source

Contributions to an improved phenytoin monitoring and dosing in hospitalized patients [PDF]

, 2016
Phenytoin (PHT) is one of the mostly used and well established anticonvulsants for the treatment of epilepsy and a standard in the antiepileptic prophylaxis in adults with severe traumatic brain injuries before and after neurosurgical intervention. Its
Tobler-Giger, Andrea
core   +1 more source

ANZTCT cytomegalovirus practice survey for allogeneic haemopoietic stem cell transplant and cellular therapy recipients in Australia and New Zealand

Internal Medicine Journal, EarlyView.
Abstract Background Despite pre‐emptive treatment (PeT), cytomegalovirus (CMV) disease and reactivation remain a clinical concern. In Australia and New Zealand (ANZ), variability exists in the management of CMV for haematopoietic stem cell transplantation (HSCT) recipients.
Andrea Henden, Lynette Chee, Julia Clark, Rachel Conyers, Julian Cooney, Richard Doocey, David Gottlieb, Tim Prestidge, Madeleine Powys, Philip Selby, Gaurav Sutrave, Eric Wong, Michelle K. Yong, Nada Hamad   +13 more
wiley   +1 more source

Long-term treatment and poor management of psychiatric manifestations in mesial temporal sclerosis leading to suicidality in a young male

Epilepsy and Behavior Case Reports, 2014
Psychiatric disorders including anxiety, psychosis, and aggressive behaviors are frequently diagnosed in patients with epilepsy. In this communication, we report a patients with mesial temporal lobe sclerosis with interictal affective-somatoform ...
Archana Verma, Alok Kumar, Atul Mishra, A.K. Pandey   +3 more
doaj   +1 more source

Multiple Episodes of Phenytoin Toxicity in an Elderly Patient

, 1997
Objective: To describe a case involving multiple episodes of phenytoin toxicity leading to hospitalization over a period of 13 months in an elderly man and to review the risk factors contributing to drug toxicity in this individual.
Augustine S Aruna, Anjali A Namjoshi
core   +1 more source

Phenytoin-induced toxicity in the postnatal cerebellar development in rat: effect of calotropis procera on selective biochemical and haematological variables [PDF]

, 2011
Phenytoin, an antiepileptic drug is used in managing seizures. Phenytoin-associated oxidative stress causes cellular damage by the generation of free radicals.
IO Imosemi, Imosemi, IO, AA Osinubi, Osinubi, AA, JA Olagunju, Olagunju, JA, LC Saalu, Saalu, LC   +7 more
core   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Catharanthus roseus‐Assisted Synthesis of Zirconia Nanoparticles for Electrochemical Determination of Nitrobenzene

ChemElectroChem, Volume 13, Issue 22, 17 November 2026.
A biogenic Catharanthus roseus‐assisted zirconia nanoparticles (CR‐ZrO2 NPs) modified glassy carbon electrode is developed for the electrochemical detection of nitrobenzene (NB). The platform offers reliable detection with high selectivity, stability, and accuracy.
Jemibha P., Karmegam Muthukrishnan, Venkatachalam Vinothkumar, Chandrasekaran Dhanush, Darlin Mary A., Tae Hyun Kim   +5 more
wiley   +1 more source

Ataxia and Seizures despite Phenytoin: A Case Report Highlighting the Importance of TDM and Genetic Influences

Case Reports in Neurological Medicine
Adverse drug reactions to commonly prescribed medications such as phenytoin, used for seizures, often go undetected due to various factors. This case report highlights a 52-year-old male diagnosed with late-onset epilepsy who was prescribed phenytoin ...
Rachel Manoj, Arpita Meher, Jefry Winner G.   +2 more
doaj   +1 more source

Non-hyperammonaemic valproate encephalopathy after 20 years of treatment

Epilepsy and Behavior Case Reports, 2017
Sodium valproate is a commonly used antiseizure drug with broad indications for different seizuretypes and epilepsy syndromes. Well-recognised side effects include weight gain, tremor, dizziness, and unsteadiness.
Elizabeth Caruana Galizia, Jeremy D. Isaacs, Hannah R. Cock   +2 more
doaj   +1 more source