Results 131 to 140 of about 6,040 (161)

Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci. [PDF]

Nat Commun
Hecker D, Song X, Baumgarten N, Diagel A, Katsaouni N, Li L, Li S, Kumar Maji R, Behjati Ardakani F, Ma L, Li Z, Moggio A, Tews D, Sager H, Maegdefessel L, Wabitsch M, Björkegren JLM, Schunkert H, Chen Z, Schulz MH.   +19 more
europepmc   +1 more source

Reduced order computational fluid dynamic simulations in the thoracic aorta are associated with disease recorded in a medical biobank. [PDF]

Sci Rep
Sokolow R, Bhattacharya A, Kissas G, Thompson EW, Beeche C, Swago S, Zhang D, Viswanadha M, Morse C, Chirinos J, Damrauer S, Verma A, Perdikaris P, Rader DJ, Witschey WR, Penn Medicine Biobank.   +15 more
europepmc   +1 more source

Potential of <i>SP1</i> as a prognostic marker and therapeutic target in acute myocardial infarction: a bioinformatics, Mendelian randomization and experimental validation study. [PDF]

Front Immunol
Li Z, Cheng H, Li J, Guan X, Wen N, Wang L.   +5 more
europepmc   +1 more source

A Phenome-Wide Mendelian Randomization and Colocalization Study Reveals Genetic Association Between PBC and Other Autoimmune Disorders. [PDF]

Can J Gastroenterol Hepatol
Shi S, Liu M, Gao H, Liu F, Song Y.
europepmc   +1 more source

SNP rs7549881, near SGIP1 at 1p31.3, is significantly associated with digestive disorders and Parkinsonism in women. [PDF]

Clin Park Relat Disord
Lehrer S, Rheinstein P.
europepmc   +1 more source

Identification of breast cancer susceptibility genes via trans-ethnic Mendelian randomization and colocalization analyses. [PDF]

Medicine (Baltimore)
Huang K, Huang H, Ma LL, Liu Y, Li Q.
europepmc   +1 more source

Proteome-wide mendelian randomization reveals circulating proteins causally associated with childhood body mass index. [PDF]

Sci Rep
Avocegamou R, Jumentier B, Fagbemi K, Yazdanpanah N, Yazdanpanah M, Gamache I, Manousaki D.   +6 more
europepmc   +1 more source

Enhanced pain relief with guanfacine as an adjuvant for trigeminal nerve blocks: insights from a PheWAS-guided randomized controlled study. [PDF]

Pain Med
Meier SE, Orr MB, Shotwell MS, Jerome RN, Shirey-Rice JK, Pulley JM, Edwards DA, Toye AD, Mishra P, Kesayan T.   +9 more
europepmc   +1 more source

Cross-trait genomic modeling reveals the polygenic architecture and systemic impact of MASLD. [PDF]

Sci Adv
Du M, Yuan H, Wu T, Jiang Y, Suo C, Jin L, Zhang T, Liu Z, Chen X.   +8 more
europepmc   +1 more source

Leveraging Large and Diverse Biobanks to Evaluate Gene-Disease Associations in Hypertrophic Cardiomyopathy. [PDF]

J Pers Med
Dababneh SF, Ong K, Yeung D, Hawkins NM, Krahn A, Laksman Z, Tadros R, Roston TM.   +7 more
europepmc   +1 more source