Results 121 to 130 of about 6,040 (161)

The associations between diet-induced inflammation and health outcomes: a population-based phenome-wide association study. [PDF]

NPJ Sci Food
Chen W, Liu K, Jing X, Qian Y, Liu B, Chen Y, Li J, Sun X, Mao Y, Ye D.   +9 more
europepmc   +1 more source

Rare variant analyses provide insights into the genetic architecture of endometriosis. [PDF]

Hum Genomics
Gui Y, Xie Y, Tong X, Zhao H.
europepmc   +1 more source

Identification and genetic validation of potential therapeutic targets for pulmonary hypertension through multi-omics causal inference. [PDF]

Medicine (Baltimore)
Wu C, Zhao W, Zhu X, Li Y, Chen Z, Yan X.   +5 more
europepmc   +1 more source

Genetic regulation across germline and somatic variation on the Y chromosome contributes to type 2 diabetes. [PDF]

Nat Med
Sato G, Yamamoto Y, Sonehara K, Saiki R, Ojima T, Kanai M, Liu A, Edahiro R, Shirai Y, Namba S, Namkoong H, Hasaegawa T, Koyanagi YN, Kasugai Y, Yamaji T, Nakano S, Genovese G, Sipilä TP, Ghazal A, Tanaka H, Azekawa S, Uwamino Y, Yamamoto K, Suzuki K, Hata T, Uemura M, Takeda Y, Kanai A, Higashiue S, Kobayashi S, Afuso H, Matsuura K, Mitsumoto Y, Fujita Y, FinnGen, Japan COVID-19 Task Force, Biobank Japan Project, Oda Y, Suzuki Y, Morisaki T, Ishii M, Kitagawa Y, Koike R, Kimura A, Imoto S, Miyano S, Kanai T, Takayama J, Iwasaki M, Sawada N, Fukunaga K, Matsuo K, Kumanogoh A, Doki Y, Eguchi H, Nakagome S, Tamiya G, Ganna A, Palotie A, Daly MJ, Wilson JF, Yamamoto M, Matsuda K, Ogawa S, Yamauchi T, Kadowaki T, Okada Y.   +66 more
europepmc   +1 more source

Integrative multi-omics analyses identify key genes and elucidate bidirectional regulatory mechanisms in thyroid dysfunction. [PDF]

PLoS One
Hu Y, Hu H, Xu L, Tang X, Wang C, Lian Z, Xie C, Xie Z, Wang Q.   +8 more
europepmc   +1 more source

Multi-omics Mendelian randomization prioritizes BMP6 as a candidate therapeutic target in intervertebral disc degeneration. [PDF]

J Orthop Surg Res
Kan S, Liu W, Li P, Zhou M, Yu H, Zheng Y, Hu W, Zhu R.   +7 more
europepmc   +1 more source

Integrative multi-omics Mendelian randomization and functional validation identifies RNASET2 as a novel therapeutic target for autoimmune thyroiditis. [PDF]

Front Endocrinol (Lausanne)
Jiang B, Wang Y, Qu C, Zhang C, Jiang C, Su L, Guan W, Luo Y.   +7 more
europepmc   +1 more source

Inclusion bias affects common variant discovery and replication in a health-system linked biobank. [PDF]

Am J Hum Genet
Pimplaskar A, Qiu J, Lapinska S, Tozzo V, Chiang JN, Pasaniuc B, Olde Loohuis LM.   +6 more
europepmc   +1 more source

Proteome-wide Mendelian randomization identifies drug targets for atrial fibrillation/flutter. [PDF]

BMC Cardiovasc Disord
Jia Q, Yang Y, Chen X, Hu Z.
europepmc   +1 more source

Mapping the brain cell-specific regulatory architecture of migraine: a single-cell causal framework nominating inhibitory-neuronal BTBD16 and astrocytic RIMS1 as therapeutic targets. [PDF]

J Headache Pain
Ye H, Huang Y, Wang C, Jin J, Jiang C, Fang J, Xu Q.   +6 more
europepmc   +1 more source