Results 161 to 170 of about 6,310 (247)

Insights from the largest diverse ancestry sex-specific disease map for genetically predicted height

npj Genomic Medicine
We performed ancestry and sex specific Phenome Wide Association Studies (PheWAS) to explore disease related outcomes associated with genetically predicted height.
A. Papadopoulou, E. M. Litkowski, M. Graff, Z. Wang, R. A. J. Smit, G. Chittoor, I. Dinsmore, N. S. Josyula, M. Lin, J. Shortt, W. Zhu, S. L. Vedantam, L. Yengo, A. R. Wood, S. I. Berndt, I. A. Holm, F. D. Mentch, H. Hakonarson, K. Kiryluk, C. Weng, G. P. Jarvik, D. Crosslin, D. Carrell, I. J. Kullo, O. Dikilitas, M. G. Hayes, W. -Q. Wei, D. R. V. Edwards, T. L. Assimes, J. N. Hirschhorn, J. E. Below, C. R. Gignoux, A. E. Justice, R. J. F. Loos, Y. V. Sun, S. Raghavan, P. Deloukas, K. E. North, E. Marouli   +38 more
doaj   +1 more source

Constructing genotype and phenotype network helps reveal disease heritability and phenome-wide association studies

BMC Genomics
Background Analyses of a bipartite Genotype and Phenotype Network (GPN), linking the genetic variants and phenotypes based on statistical associations, provide an integrative approach to elucidate the complexities of genetic relationships across diseases
Xuewei Cao, Lirong Zhu, Xiaoyu Liang, Shuanglin Zhang, Qiuying Sha   +4 more
doaj   +1 more source

Distinguishing clinical and genetic risk factors for suicidal ideation and behavior in a diverse hospital population

Translational Psychiatry
Suicidal ideation (SI) and behavior (SB) are major public health concerns, but risk factors for their development and progression are poorly understood.
Sarah M. C. Colbert, Lauren Lepow, Brian Fennessy, Nakao Iwata, Masashi Ikeda, Takeo Saito, Chikashi Terao, Michael Preuss, Jyotishman Pathak, J. John Mann, Hilary Coon, Niamh Mullins   +11 more
doaj   +1 more source

Limnological Pre-survey of Lake Phewa, Nepal

Limnological Pre-survey of Lake Phewa, Nepal
Article 信州大学理学部紀要 15(1): 27-29(1980)
openaire   +1 more source

PheWAS and Pharmacophenomics in Precision Medicine and TraditionalChinese Medicine

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018
Duan, Dayue Darrel, Ye, Lingyu Linda, Yang, Si-jin   +2 more
openaire   +2 more sources

Phenome- and laboratory-wide meta-analyses of sickle cell trait reveal multi-system disease associations. [PDF]

Am J Hum Genet
Hysong MR, Shuey MM, Miller-Fleming TW, Keat K, Stilp AM, Li Y, Cox NJ, Auer PL, Franceschini N, Verma A, Raffield LM, Reiner AP.   +11 more
europepmc   +1 more source

Integrative Proteome-Wide Mendelian Randomization and Multi-Omics Analysis Identify ADM and CFH as Candidate Genes for Osteoarthritis. [PDF]

Biomedicines
Li H, Gong D, Yang J, Wang Z, Lv J, Guo C.   +5 more
europepmc   +1 more source

Genetic variation in macrophage-restricted FOLR2 is associated with neurodevelopmental and reproductive immune phenotypes. [PDF]

Front Immunol
Jasper EA, Jaworski J, Luo Y, Khales BN, Khan A, Edwards DRV, Aronoff DM.   +6 more
europepmc   +1 more source

Proteome-wide Mendelian randomisation of lung function to identify potential therapeutic targets for respiratory disease. [PDF]

ERJ Open Res
Chen J, Shrine N, Coley K, Packer RJ, Edris A, Izquierdo AG, Lim B, Lee M, Dudbridge F, Walters RG, Hall IP, Wain LV, Tobin MD, Guyatt AL, SpiroMeta Consortium and the CHARGE consortium.   +14 more
europepmc   +1 more source

Exploring the Pleiotropic Genetic Architecture of Substance Use Disorders: Findings From Phenome-Wide Association Studies. [PDF]

Biol Psychiatry Glob Open Sci
Hartwell EE, Kember RL.
europepmc   +1 more source