Results 181 to 190 of about 6,310 (247)

Genetic Identification of Potential Drug Targets for Dental Caries: A Mendelian Randomization Study. [PDF]

Health Sci Rep
Bi J, Liu A, Zhang N, Chen Y, Liu C, Zhu Y, Wen H, Ma C.   +7 more
europepmc   +1 more source

PheWAS-TTE： An Innovative Framework for Identifying Drug Additional Benefits and Potential Risks

Scientia Sinica Vitae
Tianjunke Zhou, Ding-Fa Liang, Hao Liu, Ting-Jie Zhao, Jie Wei, L. Houchen   +5 more
semanticscholar   +1 more source

Correction: GWAS analysis of a depression cohort defined by an EHR-phenotyping algorithm reveals the role of immune regulations in depression risk. [PDF]

Front Genet
Xian S, Carrell D, Smoller JW, Wei WQ, Jarvik GP, Crosslin DR.   +5 more
europepmc   +1 more source

Integrative Multi-Omics Mendelian Randomization Identifies BLMH as a Keratinocyte-Enriched Protective Candidate Gene and Potential Therapeutic Target in Psoriasis. [PDF]

J Inflamm Res
Shen R, Ran B, Liu J, Li X, Cao H, Liu Q, Liang B, Xie M, Hou J, Gao J.   +9 more
europepmc   +1 more source

SMR Analysis Integrating GWAS and eQTL Data Reveals UHRF1BP1 and SNRPC as Potential Drug Targets for Low Back Pain. [PDF]

J Pain Res
Xie XY, Lin JW, Li PC, Fang JY, Chen ZC, Huang XY, Cao MH, Lin LL, Guo MY.   +8 more
europepmc   +1 more source

Locus-specific stratification and prioritization unveil genetic risk mechanism underlying complex diseases. [PDF]

Nat Commun
Zhang J, Liu Q, Zhu Y, Xia L, Wang K, Guo Y, Gong L, Liu Z, Qin Z, Shi S, Yang J.   +10 more
europepmc   +1 more source

Mendelian Randomization Unveils Poly(ADP-ribose) Polymerase 1 as Causal Plasma Protein Target in Melanoma, Integrated Multi-omics. [PDF]

Plast Reconstr Surg Glob Open
Lu F, Luan W, Jiang H, Ma S, Ruan H.
europepmc   +1 more source

Endothelial EPAS1 as a prognostic and therapeutic target in acute myocardial infarction: integrative bioinformatics, Mendelian randomization and experimental validation. [PDF]

Front Pharmacol
Yang X, Li Z, Guo L, Li J, Cheng H, Guan X, Wen N, Wang H, Li L, Yang L, Zhu Y, Wang L.   +11 more
europepmc   +1 more source

Guanfacine as a potential preventive therapy for chronic migraine: a mechanistic hypothesis. [PDF]

Front Neurol
Kesayan T, Patel K.
europepmc   +1 more source

Unveiling novel susceptibility genes for sarcoidosis by a cross-tissue transcriptome-wide association study. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Sun X.
europepmc   +1 more source