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Therapeutic
ObjectiveDelivery of therapeutic agents to the cornea is a difficult task in the treatment of parasitic keratitis. In this study, we looked at using different combinations of ultrasound parameters to enhance corneal permeability to polyhexamethylene biguanide (PHMB), a clinically available ophthalmic antiparasitic formulation.MethodsPermeability of ...
Bianca Karpinecz +2 more
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PHMB-loaded PDMS and its antimicrobial properties for biomedical applications
Journal of Biomaterials Applications, 2021Given the global panorama of demands in the health area, the development of biomaterials becomes irreducible for the maintenance and/or improvement in the quality of life of the human being. Aiming to reduce the impacts related to infections in the healing processes of the dermal structure, the present work proposes the development of ...
Micael Montemezzo +9 more
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Polyhexamethylenbiguanid (PHMB) als Therapieoption bei Fusarienkeratitis
Klinische Monatsblätter für Augenheilkunde, 2012Hintergrund: Durch Pilze verursachte Augeninfektionen werden zunehmend beobachtet. Weltweit dominieren Fusarium species, welche haufig nicht auf Standardtherapien ansprechen. Methoden: Wir berichten uber 3 Patienten mit Kontaktlinsen assoziierten Fusarienkeratitiden, die mit Polyhexamethylenbiguanid (PHMB) behandelt wurden.
W Hofmüller +5 more
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Kinetics of Adsorption and Desorption of PHMB from Textile Surfaces
AATCC Journal of Research, 2021Adsorption and desorption studies were done of polyhexamethylene biguanide (PHMB) onto two different types of textile fiber surfaces. Based on these studies and mathematical modelling, the rate constants were calculated. Two different experimental conditions were used to simulate laundering, namely wet-to-wet and dry-to-wet.
Usha Bhaskara +3 more
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PHMB: an effective antimicrobial in wound bioburden management
British Journal of Nursing, 2012The effective management of bacterial bioburden is an essential element of wound care. Recent years have seen the increased use of topical antimicrobial dressings to control colonisation and infection, yet there is concern that some may inhibit wound healing and may have systemic sequelae ( World Union of Wound Healing Societies (WUWHS), 2008 ).
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Journal of Hazardous Materials, 2021
Bacterial associated infection is a remaining urgent challenge in clinic application of metallic implants and devices. Here, we developed a new strategy to combat the bacterial associated infection of titanium alloy (TC4). Novel phosphonate/active ester block polymers (pDEMMP-b-pNHSMA) with identical phosphonate segments (DP = 29) as the metal ...
Jiangmei, Peng +8 more
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Bacterial associated infection is a remaining urgent challenge in clinic application of metallic implants and devices. Here, we developed a new strategy to combat the bacterial associated infection of titanium alloy (TC4). Novel phosphonate/active ester block polymers (pDEMMP-b-pNHSMA) with identical phosphonate segments (DP = 29) as the metal ...
Jiangmei, Peng +8 more
openaire +2 more sources
Polyhexamethylene Biguanide (PHMB) in the Treatment of Experimental Fusarium Keratomycosis
Cornea, 1997We wanted to determine whether topical polyhexamethylene biguanide (PHMB) 0.02% was effective in the treatment of experimental Fusarium keratomycosis in rabbits.Fusarium solani keratomycosis was induced in the eyes of 12 New Zealand white rabbits. The rabbits were treated with PHMB 0.02% in one eye and placebo in the other eye for 6 days.
R G, Fiscella +5 more
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Preparation and characterization of PHMB-based multifunctional microcapsules
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2017Abstract Insects and microbes can cause disease and corrode materiel deployed in humid environments. Materials with multifunctional properties are highly desirable to the Army to create textile products that would inherently mitigate these issues and decrease Soldier load.
Laura W. Place +2 more
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