Results 71 to 80 of about 1,235,785 (183)

LurR is a regulator of the central lactate oxidation pathway in sulfate-reducing Desulfovibrio species.

open access: yesPLoS ONE, 2019
The central carbon/lactate utilization pathway in the model sulfate-reducing bacterium, Desulfovibrio vulgaris Hildenborough, is encoded by the highly conserved operon DVU3025-3033.
Lara Rajeev   +7 more
doaj   +1 more source

Kā pao te tōrea: Opportunities to Improve Oral Health Services for Māori

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objective Colonisation continues to shape Indigenous health outcomes today. Māori are the Indigenous people of Aotearoa New Zealand, and experience barriers to accessing care and a greater prevalence of dental caries, periodontal diseases, and tooth loss compared with non‐Māori.
J. Kuramaiki Lacey   +3 more
wiley   +1 more source

Genome-Wide Ultrabithorax Binding Analysis Reveals Highly Targeted Genomic Loci at Developmental Regulators and a Potential Connection to Polycomb-Mediated Regulation.

open access: yesPLoS ONE, 2016
Hox homeodomain transcription factors are key regulators of animal development. They specify the identity of segments along the anterior-posterior body axis in metazoans by controlling the expression of diverse downstream targets, including transcription
Daria Shlyueva   +3 more
doaj   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Saint Louis University Billikens vs. Washington University Bears

open access: yes, 1969
SLU Billikens vs Washington University Bears at Musial Field in St. Louis, MO. SLU won this game 8-0.
Lukaszewski, B. T.
core   +3 more sources

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

open access: yesThe FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon   +4 more
wiley   +1 more source

Unveiling biodegradation mechanism of phoxim: Novel metabolic pathway, functional gene, detoxification effect, and widespread distribution of phoA

open access: yesEnvironment International
Phoxim, an organophosphorus insecticide (OP), poses risks to non-target organisms in the environment. However, the biodegradation mechanism of phoxim was not fully understood.
Qian Li   +8 more
doaj   +1 more source

Re‐Walking Betweenness: Augmented Reality as a Pedagogy of Geo‐Historical Justice

open access: yesInternational Journal of Art &Design Education, EarlyView.
Abstract This article proposes a pedagogical approach that mobilises AR as an apparatus within artistic practice, examining how augmented reality and hauntological walking generate embodied encounters that reconfigure spatial justice through decolonial and relational walking practices.
Pei‐Jung Tsai
wiley   +1 more source

The TaRNS4–TaPP2C10 module regulates wheat resistance to stripe rust through RNA degradation and MAPK cascades

open access: yesJournal of Integrative Plant Biology, EarlyView.
In wheat, phosphorylation of the S‐like RNase TaRNS4 mediated by the kinase TaRLK5 promotes its degradation of Puccinia striiformis f. sp. tritici RNA in the apoplast, enhancing resistance to stripe rust. TaRNS4 can hijack phosphatase TaPP2C10 to relieve its dephosphorylation of TaMAPK6, thereby activating MAPK‐mediated immune responses. ABSTRACT RNase
Qiao Wang   +8 more
wiley   +1 more source

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