Results 71 to 80 of about 7,818 (149)

Advising on Antidepressant Use in Pregnancy: Are We All on the Same Page?

Asia-Pacific Psychiatry, Volume 18, Issue 3, September 2026.
ABSTRACT Purpose Perinatal mood disorders are associated with adverse maternal and neonatal outcomes and affect 15%–20% of pregnant people. Guidelines recommend SSRIs when non‐pharmacological therapies are ineffective, yet antenatal depression remains undertreated.
Lucy Charlotte Broughton, Natalie Hughes, Jiaxu Zeng, Alesha Smith   +3 more
wiley   +1 more source

Antioxidant and Cytotoxic Properties of Piper spp. Volatile Oils That Inhibit Pathogenic Microorganisms

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 935-942, July 2026.
The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira, Ely D. Alfaia Neto, Carlos Eduardo C. Alves, Renata Galvão de Azevedo, Alice F. Gomes, Flávia Juliana Reis de Sousa, Juan Campos de Oliveira, Larissa Raquel S. Maciel, Gemilson S. Pontes, Ari F. Hidalgo, Antonia Q. L. Souza, Rita C. Saraiva Nunomura   +11 more
wiley   +1 more source

PrimaDORAC: An improved Web Interface for Rapid GAFF2 Parameter Assignment with ABCG2 Charge Models for Drug Design Applications

Journal of Computational Chemistry, Volume 47, Issue 17, 30 June 2026.
A web‐enabled implementation of the ABCG2 charge model within the PrimaDORAC platform provides frictionless GAFF2 ligand parameterization. Systematic chemical‐space analysis reveals class‐dependent correlations and structured deviations relative to AM1‐BCC, facilitating informed adoption of next‐generation electrostatic models in computational drug ...
Piero Procacci
wiley   +1 more source

Copper Complexes with Arylated Triethylenetetramine Ligands: Reactivity Toward Dioxygen and Peroxides

European Journal of Inorganic Chemistry, Volume 29, Issue 17, 17 June 2026.
Here, we describe new Cu(I)/Cu(II) complexes based on arylated tren ligands and investigate their reactivity toward O2 and peroxides. Low‐temperature–stopped flow studies revealed the formation of transient copper–oxygen species, including superoxido, hydroperoxido, and alkylperoxido intermediates.
Chiara Eleonora Campi, Christian Würtele, Siegfried Schindler   +2 more
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Polyurethane Depolymerization With Alkyl, Aryl, and Mixed Carbonates

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
The depolymerization of polyurethane foams strongly depends on carbonate structure. Aryl carbonates improve hard‐segment solubility but generate side products. Alkyl carbonates give cleaner products yet suffer from limited hard‐block solubility and require anisole as a cosolvent. Mixed carbonate systems balance these effects, improving solubility while
Ege Hosgor, Ricardo P. Martinho, Willem Verboom, Jean‐Paul Lange, Jurriaan Huskens   +4 more
wiley   +1 more source

The compensatory enrichment of sphingosine-1-phosphate on HDL in FSGS enhances the protective function of glomerular endothelial cells compared to MCD

Scientific Reports
Glomerular endothelial cells (GECs) are pivotal in developing glomerular sclerosis disorders. The advancement of focal segmental glomerulosclerosis (FSGS) is intimately tied to disruptions in lipid metabolism.
Yunfeng Xiong, Qiuping Ye, Lifang Liu, Wanjun Lin, Yonggen Liao, Ruiyu Gao, Jiaming Xu, Xinyu Zhang, Ruoyan Chen, Sihui Chen, Qiaoling Chen, Lixin Wei   +11 more
doaj   +1 more source

Identification of two phosphorylated species of β-catenin involved in the ubiquitin-proteasome pathway by using two-dimensional Phos-tag affinity electrophoresis

Journal of Electrophoresis, 2014
Kinoshita-Kikuta, Emiko, Kinoshita, Eiji, Koike, Tohru   +2 more
openaire   +2 more sources

Elevated calcitonin gene-related peptide expression through prostaglandin E2-EP4 receptor pathway in promoting proliferative periosteum formation in primary hypertrophic osteoarthropathy. [PDF]

J Orthop Translat
Pang Q, Zhou R, Li Y, Huang L, Xu J, Chi Y, Qi X, Li M, Jiang Y, Wang O, Xing X, Qin L, Xia W.   +12 more
europepmc   +1 more source

<i>Burkholderia vietnamiensis</i> genes involved in extracellular medium-chain-length polyhydroxyalkanoate degradation. [PDF]

Appl Environ Microbiol
Yap ZL, Yi S, Quintana E, García LG, Safklou M, Darragh R, Hogan AM, Motnenko A, Blunt W, Sparling R, Fernández Do Porto D, Levin DB, Cardona ST.   +12 more
europepmc   +1 more source