Results 121 to 130 of about 823,820 (320)

Strigolactones spatially influence lateral root development through the cytokinin signaling network [PDF]

, 2015
Strigolactones are important rhizosphere signals that act as phytohormones and have multiple functions, including modulation of lateral root (LR) development.
Beeckman, Tom, Boyer, François-Didier, De Cuyper, Carolien, De Keyser, Annick, Depuydt, Stephen, Goormachtig, Sofie, Jiang, Lingxiang, Marquez-Garcia, Belen, Matthys, Cedrick, Smet, Lien   +9 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Roles of Pho regulon in bacterial pathogenicity

Virulence
Bacterial infections are a leading cause of global health loss. The prerequisites for bacteria to colonize and establish systemic infection in the host are environmental adaptability and the expression of virulence factors.
Jing Yang, Min Wang, Yi Wang, Rui Qiang, Qiyuan Jin, Chenhao Zhao, Qi Chen, Mingxiao Han, Xin Ma, Haifang Zhang   +9 more
doaj   +1 more source

Integration of P, S, Fe and Zn nutrition signals in Arabidopsis thaliana : potential involvement of PHOSPHATE STARVATION RESPONSE 1 (PHR1).

Frontiers in Plant Science, 2015
Phosphate and sulfate are essential macro-elements for plant growth and development, and deficiencies in these mineral elements alter many metabolic functions. Nutritional constraints are not restricted to macro-elements.
Jean-Francois eBRIAT, Hatem eROUACHED, Nicolas eTISSOT, Frederic eGAYMARD, Christian eDUBOS   +4 more
doaj   +1 more source

Molecular interaction between PHO2 and GIGANTEA reveals a new crosstalk between flowering time and phosphate homeostasis in Oryza sativa [PDF]

, 2017
Shuai Li, Yinghui Ying, David Secco, Chuang Wang, Reena Narsai, James Whelan, Huixia Shou   +6 more
openalex   +1 more source

Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate). [PDF]

, 2019
Chronic kidney disease (CKD) is a major cause of morbidity and premature mortality and represents a significant global public health issue. Underlying this burden are the many complications of CKD, including mineral and bone disorders, anemia, and ...
Bino, Avi, Ganz, Tomas, Salusky, Isidro B   +2 more
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Acidocalcisome-like vacuoles constitute a feedback-controlled phosphate buffering system for the cytosol

eLife
Cells experience strong variations in the consumption and availability of inorganic phosphate (Pi). Since Pi is an essential macronutrient but excess Pi has negative impacts on nucleotide hydrolysis and metabolism, its concentration must be maintained in
Samuel Bru, Lydie Michaillat Mayer, Geun-Don Kim, Danye Qiu, Henning J Jessen, Andreas Mayer   +5 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The phosphate regulon and bacterial virulence: a regulatory network connecting phosphate homeostasis and pathogenesis [PDF]

, 2008
Martin G. Lamarche, Barry L. Wanner, Sébastien Crépin, Josée Harel   +3 more
openalex   +1 more source