Results 31 to 40 of about 272,636 (196)

Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast

open access: yesmBio, 2022
Inositol pyrophosphate (IPP) dynamics govern expression of the fission yeast phosphate homeostasis regulon via their effects on lncRNA-mediated transcription interference.
Beate Schwer   +5 more
doaj   +1 more source

Probing in vivo RNA Structure With Optimized DMS-MaPseq in Rice

open access: yesFrontiers in Plant Science, 2022
RNA transcripts form various secondary and tertiary structures that have a wide range of regulatory functions. Several methods have been developed to profile in vivo RNA secondary structure in prokaryotes and eukaryotes.
Qiongli Jin   +4 more
doaj   +1 more source

Regulation of plant biotic interactions and abiotic stress responses by inositol polyphosphates

open access: yesFrontiers in Plant Science, 2022
Inositol pyrophosphates (PP-InsPs), derivatives of inositol hexakisphosphate (phytic acid, InsP6) or lower inositol polyphosphates, are energy-rich signaling molecules that have critical regulatory functions in eukaryotes. In plants, the biosynthesis and
Esther Riemer   +7 more
doaj   +1 more source

Why exercise builds muscles: Titin mechanosensing controls skeletal muscle growth under load [PDF]

open access: yes, 2021
Muscles sense internally generated and externally applied forces, responding to these in a coordinated hierarchical manner at different time scales. The center of the basic unit of the muscle, the sarcomeric M-band, is perfectly placed to sense the different types of load to which the muscle is subjected.
arxiv   +1 more source

Dysregulating PHO Signaling via the CDK Machinery Differentially Impacts Energy Metabolism, Calcineurin Signaling, and Virulence in Cryptococcus neoformans

open access: yesmBio, 2023
Fungal pathogens uniquely regulate phosphate homeostasis via the cyclin-dependent kinase (CDK) signaling machinery of the phosphate acquisition (PHO) pathway (Pho85 kinase-Pho80 cyclin-CDK inhibitor Pho81), providing drug-targeting opportunities.
Bethany Grace Bowring   +10 more
doaj   +1 more source

Genetic evidence of serum phosphate-independent functions of FGF-23 on bone.

open access: yesPLoS Genetics, 2008
Maintenance of physiologic phosphate balance is of crucial biological importance, as it is fundamental to cellular function, energy metabolism, and skeletal mineralization.
Despina Sitara   +7 more
doaj   +1 more source

Interaction and Regulation of Carbon, Nitrogen, and Phosphorus Metabolisms in Root Nodules of Legumes

open access: yesFrontiers in Plant Science, 2018
Members of the plant family Leguminosae (Fabaceae) are unique in that they have evolved a symbiotic relationship with rhizobia (a group of soil bacteria that can fix atmospheric nitrogen).
Ailin Liu   +7 more
doaj   +1 more source

Mobilization and Cellular Distribution of Phosphate in the Diatom Phaeodactylum tricornutum

open access: yesFrontiers in Plant Science, 2020
Unicellular organisms that live in marine environments must cope with considerable fluctuations in the availability of inorganic phosphate (Pi). Here, we investigated the extracellular Pi concentration-dependent expression, as well as the intracellular ...
Gianluca Dell’Aquila   +8 more
doaj   +1 more source

Phosphate Acquisition and Virulence in Human Fungal Pathogens

open access: yesMicroorganisms, 2017
The ability of pathogenic fungi to acquire essential macro and micronutrients during infection is a well-established virulence trait. Recent studies in the major human fungal pathogens Candida albicans and Cryptococcus neoformans have revealed that ...
Mélanie Ikeh, Yasmin Ahmed, Janet Quinn
doaj   +1 more source

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