Results 11 to 20 of about 642,082 (258)
mBio, 2023 Fungal pathogens uniquely regulate phosphate homeostasis via the cyclin-dependent kinase (CDK) signaling machinery of the phosphate acquisition (PHO) pathway (Pho85 kinase-Pho80 cyclin-CDK inhibitor Pho81), providing drug-targeting opportunities.
Bethany Grace Bowring +10 more
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Phosphate Transport and Homeostasis in Arabidopsis [PDF]
The Arabidopsis Book, 2002 Phosphorus (P) is an essential macronutrient for all living organisms. It serves various basic biological functions as a structural element in nucleic acids and phospholipids, in energy metabolism, in the activation of metabolic intermediates, as a component in signal transduction cascades, and the regulation of enzymes. Of the major nutrients, P is
Yves, Poirier, Marcel, Bucher
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Frontiers in Endocrinology, 2020 The Carbohydrate response element binding protein, ChREBP encoded by the MLXIPL gene, is a transcription factor that is expressed at high levels in the liver and has a prominent function during consumption of high-carbohydrate diets.
Loranne Agius +2 more
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The PPIP5K Family Member Asp1 Controls Inorganic Polyphosphate Metabolism in S. pombe
Journal of Fungi, 2021 Inorganic polyphosphate (polyP) which is ubiquitously present in both prokaryotic and eukaryotic cells, consists of up to hundreds of orthophosphate residues linked by phosphoanhydride bonds.
Marina Pascual-Ortiz +3 more
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eLife, 2023 Eukaryotic cells control inorganic phosphate to balance its role as essential macronutrient with its negative bioenergetic impact on reactions liberating phosphate.
Valentin Chabert +7 more
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LPCAT1 controls phosphate homeostasis in a zinc-dependent manner
eLife, 2018 All living organisms require a variety of essential elements for their basic biological functions. While the homeostasis of nutrients is highly intertwined, the molecular and genetic mechanisms of these dependencies remain poorly understood.
Mushtak Kisko +10 more
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Biochemical assessment of phosphate homeostasis
Archives de Pédiatrie, 2021 Phosphate homeostasis is a requirement for normal life. Phosphate is involved in the synthesis of membrane lipids, DNA, RNA, and energy-rich molecules (ATP and GTP), and the regulation of protein activity by phosphorylation/dephosphorylation. Moreover, phosphate is a component of apatite crystals, which provide stability to the bone, and is essential ...
Houillier, Pascal, Salles, Jean‐pierre
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Genetic evidence of serum phosphate-independent functions of FGF-23 on bone.
PLoS Genetics, 2008 Maintenance of physiologic phosphate balance is of crucial biological importance, as it is fundamental to cellular function, energy metabolism, and skeletal mineralization.
Despina Sitara +7 more
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Latest findings in phosphate homeostasis [PDF]
Kidney International, 2009 The kidney is a key player in phosphate balance. Inappropriate renal phosphate transport may alter serum phosphate concentration and bone mineralization, and increase the risk of renal lithiasis or soft tissue calcifications. The recent identification of fibroblast growth factor 23 (FGF23) as a hormone regulating phosphate and calcitriol metabolism and
Prié, Dominique +2 more
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Salivary phosphate as a biomarker for human diseases
FASEB BioAdvances, 2022 Phosphate is a common ingredient of the daily consumed foods and is absorbed in the intestine and is excreted in the urine through the kidney to maintain the homeostatic balance.
Mohammed S. Razzaque
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