Results 11 to 20 of about 832,790 (296)
Eukaryotic Phosphate Homeostasis: The Inositol Pyrophosphate Perspective [PDF]
Trends in Biochemical Sciences, 2017 Phosphate, as a cellular energy currency, essentially drives most biochemical reactions defining living organisms, and thus its homeostasis must be tightly regulated.
Azevedo, C, Saiardi, A
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The PPIP5K Family Member Asp1 Controls Inorganic Polyphosphate Metabolism in S. pombe
Journal of Fungi, 2021 Inorganic polyphosphate (polyP) which is ubiquitously present in both prokaryotic and eukaryotic cells, consists of up to hundreds of orthophosphate residues linked by phosphoanhydride bonds.
Marina Pascual-Ortiz +3 more
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Latest findings in phosphate homeostasis [PDF]
Kidney International, 2009 The kidney is a key player in phosphate balance. Inappropriate renal phosphate transport may alter serum phosphate concentration and bone mineralization, and increase the risk of renal lithiasis or soft tissue calcifications. The recent identification of fibroblast growth factor 23 (FGF23) as a hormone regulating phosphate and calcitriol metabolism and
Prié, Dominique +2 more
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Biochemical assessment of phosphate homeostasis
Archives de Pédiatrie, 2021 Phosphate homeostasis is a requirement for normal life. Phosphate is involved in the synthesis of membrane lipids, DNA, RNA, and energy-rich molecules (ATP and GTP), and the regulation of protein activity by phosphorylation/dephosphorylation. Moreover, phosphate is a component of apatite crystals, which provide stability to the bone, and is essential ...
Houillier, Pascal, Salles, Jean‐pierre
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eLife, 2023 Eukaryotic cells control inorganic phosphate to balance its role as essential macronutrient with its negative bioenergetic impact on reactions liberating phosphate.
Valentin Chabert +7 more
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Protein synthesis controls phosphate homeostasis [PDF]
Genes & Development, 2018 Phosphorus is an essential element assimilated largely as orthophosphate (Pi). Cells respond to Pi starvation by importing Pi from their surroundings. We now report that impaired protein synthesis alone triggers a Pi starvation response even when Pi is plentiful in the extracellular milieu.
Pontes, Mauricio H. +1 more
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Frontiers in Endocrinology, 2020 The Carbohydrate response element binding protein, ChREBP encoded by the MLXIPL gene, is a transcription factor that is expressed at high levels in the liver and has a prominent function during consumption of high-carbohydrate diets.
Loranne Agius +2 more
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Acclimation responses of Arabidopsis thaliana to sustained phosphite treatments [PDF]
, 2013 Phosphite () induces a range of physiological and developmental responses in plants by disturbing the homeostasis of the macronutrient phosphate. Because of its close structural resemblance to phosphate, phosphite impairs the sensing, membrane transport,
Berkowitz, O. +7 more
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Alpha Klotho and phosphate homeostasis [PDF]
Journal of Endocrinological Investigation, 2014 The Klotho family consists of three single-pass transmembrane proteins—αKlotho, βKlotho and γKlotho. Each of them combines with fibroblast growth factor (FGF) receptors (FGFRs) to form receptor complexes for various FGF’s. αKlotho is a co-receptor for physiological FGF23 signaling and appears essential for FGF23-mediated regulation of mineral ...
A, Bian, C, Xing, M C, Hu
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LPCAT1 controls phosphate homeostasis in a zinc-dependent manner
eLife, 2018 All living organisms require a variety of essential elements for their basic biological functions. While the homeostasis of nutrients is highly intertwined, the molecular and genetic mechanisms of these dependencies remain poorly understood.
Mushtak Kisko +10 more
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