Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
MINERAL FORMS OF PHOSPHORUS IN OOIDAL IRON ORES OF THE MARSYATY DEPOSIT (NORTHERN URALS) [PDF]
Horizons enriched in phosphorus are identified in ooidal ironstones underlying the oxidecarbonate manganese ores of the Marsyaty deposit (Northern Urals). The maximum P2O5 content reaches 6.37 wt. % in a quartz sandstone interbed with ooids consisting of
E.V. Belogub+4 more
doaj +1 more source
An Outbreak of Tri-ortho-cresyl Phosphate (T.O.C.P.) Poisoning in Durban [PDF]
Mervyn Susser, Zena Stein
openalex +1 more source
Research of Calcium Phosphates Using Fourier Transform Infrared Spectroscopy
In the biomaterial research field, nowadays a great attention is driven onto calcium phosphates synthesis and obtaining of ceramics that can be used in orthopedics and dentistry, in the form of coatings, granules, porous or solid blocks, as well as in ...
L. Bērziņa-Cimdiņa+1 more
semanticscholar +1 more source
Metal-catalyzed double migratory cascade reactions of propargylic esters and phosphates.
Propargylic esters and phosphates are easily accessible substrates, which exhibit rich and tunable reactivities in the presence of transition metal catalysts.
Roohollah Kazem Shiroodi, V. Gevorgyan
semanticscholar +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Dynamics of ion-phosphate lattice of DNA in left-handed double helix form [PDF]
The conformational vibrations of Z-DNA with counterions are studied in framework of phenomenological model developed. The structure of left-handed double helix with counterions neutralizing the negatively charged phosphate groups of DNA is considered as the ion-phosphate lattice. The frequencies and Raman intensities for the modes of Z-DNA with Na+ and
arxiv
Serum esterases. 2. An enzyme hydrolysing diethyl p-nitrophenyl phosphate (E 600) and its identity with the A-esterase of mammalian sera [PDF]
W. N. Aldridge
openalex +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source