Results 61 to 70 of about 43,727 (248)
RASSF4: Regulator of plasma membrane PI(4,5)P2. [PDF]
, 2017 Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane-cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/
Balla +12 more
core +1 more source
Fatty Acids of Human Platelet Phosphatides.
Experimental Biology and Medicine, 1961 SummaryThe fatty acids of blood platelet phosphatides have ben studied by silicic acid, and gas-liquid chromatography. PEPS fractions contain primarily arachidonic, stearic and oleic acids. Lecithin-sphingomyelin eluates contain principally palmitic, stearic and oleic acids.
Harris L. Ullman +2 more
openaire +3 more sources
Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy
Movement Disorders, EarlyView.Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik +8 more
wiley +1 more source
Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation [PDF]
, 2014 The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 (mTOR complex 1) activation with the ...
Amy Patton +12 more
core +4 more sources
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
Medicinal Research Reviews, EarlyView.ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca +2 more
wiley +1 more source
Coordinated functional divergence of genes after genome duplication in Arabidopsis thaliana [PDF]
, 2017 Gene and genome duplications have been rampant during the evolution of flowering plants. Unlike small-scale gene duplications, whole-genome duplications (WGDs) copy entire pathways or networks, and as such create the unique situation in which such ...
De Smet, Riet +4 more
core +1 more source
Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms
Small Science, EarlyView.This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn +4 more
wiley +1 more source
U.S. Biodiesel Development: New Markets for Conventional and Genetically Modified Agricultural Products [PDF]
With environmental and energy source concerns on the rise, using agricultural fats and oils as fuel in diesel engines has captured increasing attention.
Duffield, James A. +4 more
core +1 more source
Alteration of phospholipid at various growth phases of Escherichia coli [PDF]
, 1971 By inoculating E. coli B into the semisynthetic medium we conducted shaking culture, and observed alterations of the total phospholipid contents and the amounts of individual phospholipid components in various stages of growth.
Ichikawa, Hiroyuki +3 more
core +1 more source
VIEW, EarlyView.Enzymatically derived tissue debris (TD) is utilized to establish patient‐derived lung cancer tissue spheres (LCOs), which, in conjunction with mass spectrometry imaging, enable the investigation of tumor metabolic heterogeneity and maintenance of CSCs.
Ling Guo +6 more
wiley +1 more source