Results 51 to 60 of about 26,600 (143)

An OsSK12/13‐OsERF60‐OsHsfA2c module regulates heat stress tolerance in rice

Journal of Integrative Plant Biology, EarlyView.
The heat‐induced GSK3‐like kinases OsSK12 and OsSK13 phosphorylate and stabilize the transcription factor OsERF60, which activates the expression of downstream genes including the heat shock factor gene OsHsfA2c. This regulatory module governs heat‐responsive gene induction, representing a mechanistic target for enhancing crop resilience under climate ...
Juan Gao, Zi‐Wei Yao, Zhi‐Ping Deng, Jing‐Jing Wang, Dong‐Jie Zhu, Dai‐Xi Yue, Hai‐Ping Lu, Jian‐Xiang Liu   +7 more
wiley   +1 more source

Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates

Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.
An alkyne‐tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the Kennedy pathway, allowing CuAAC‐based visualization of PE and affinity capture of PE‐conjugated LC3, ubiquitin, and GPI‐anchored proteins.
Yuan‐Ting Cho, Cindy Y. Jao, Zijun Xia, Brittany M. White‐Mathieu, Adrian Salic, Jeremy M. Baskin   +5 more
wiley   +2 more sources

Role of Lipin‐1 in Macrophage‐Mediated Atherosclerosis: Is It Atherogenic or Atheroprotective?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Macrophages are central regulators of atherosclerosis, governing lipid accumulation, inflammatory signaling, and plaque stability. Lipin‐1 is a multifunctional lipid–metabolic regulator that integrates cellular metabolism with inflammatory responses ...
Farnaz Oghbaei, Maryam Musavi, Mohammad Abavisani, Ramin Raoufinia, Ahmad Ghasemi, Amir Abbas Momtazi‐Borojeni   +5 more
doaj   +1 more source

Metabolism of glycerolipids: V. Metabolism of phosphatidic acid

Journal of Lipid Research, 1964
Monoacyl glycerol phosphate is acylated more rapidly than glycerol-3-phosphate by microsomal preparations from rat or guinea pig liver.Specifically labeled diacyl glycerol phosphate derivatives were prepared.
William E.M. Lands, Priscilla Hart
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Cytotoxicity mechanism of heterologous expression of phospholipase D in Escherichia coli

Microbiology Spectrum
Phospholipase D (PLD) has multiple functions in cells and various industrial applications, including the production of high-purity and rare phospholipids, making it a highly valuable enzyme.
Shaofeng Chen, Rongxin Wu, Xiaoyun Guo, Shuizhi Lin, Yinghua Lu, Xueping Ling   +5 more
doaj   +1 more source

Phosphatidic Acid: From Pleiotropic Functions to Neuronal Pathology

Frontiers in Cellular Neuroscience, 2019
Among the cellular lipids, phosphatidic acid (PA) is a peculiar one as it is at the same time a key building block of phospholipid synthesis and a major lipid second messenger conveying signaling information.
Emeline Tanguy, Qili Wang, Hervé Moine, Nicolas Vitale   +3 more
doaj   +1 more source

Multiplex FAD2/FATB Editing Generates Ultra‐High‐Oleic, Low‐Saturate Soybean With Increased Seed Fatty Acid Content

Plant Biotechnology Journal, EarlyView.
ABSTRACT Oleic acid (18:1), saturated fatty acid (SFA), and polyunsaturated fatty acid (PUFA) levels are important traits for storage stability and edibility. In this study, we aimed to develop high‐oleic soybean (Glycine max) by simultaneously targeting fatty acid desaturase 2 (FAD2) and fatty acyl‐ACP thioesterase B (FATB) gene families using CRISPR ...
Won Nyeong Kim, Yu‐Ri Choi, Hye Jeong Kim, Young‐Soo Chung, Hyun Uk Kim   +4 more
wiley   +1 more source

Evaluation of the Use of Phosphatidic Acid in the Diet on Growth Performance and Breast Meat Yield in Broilers

Animals, 2018
The use of feed additives to improve feed conversion while increasing growth is the goal of any broiler nutrition program. Therefore, it is important to evaluate potential feed additives not only for increased performance, but also for any negative ...
Eric B. Sobotik, Jason T. Lee, Scott Hagerman, Gregory S. Archer   +3 more
doaj   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source