Results 51 to 60 of about 3,207 (207)

Interaction of the Spo20 membrane-sensor motif with phosphatidic acid and other anionic lipids, and influence of the membrane environment.

open access: yesPLoS ONE, 2014
The yeast protein Spo20 contains a regulatory amphipathic motif that has been suggested to recognize phosphatidic acid, a lipid involved in signal transduction, lipid metabolism and membrane fusion.
Habib Horchani   +3 more
doaj   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

open access: yesInterdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu   +6 more
wiley   +1 more source

Crystal structure of a lipin/Pah phosphatidic acid phosphatase

open access: yesNature Communications, 2020
Lipin/Pah phosphatidic acid phosphatases generate diacylglycerol to regulate triglyceride synthesis and cellular signaling. Here authors determine structures of Tetrahymena thermophila Pah2 and identify an N-terminal amphipathic helix essential for ...
Valerie I. Khayyo   +6 more
doaj   +1 more source

phosphatidic acids

open access: yes, 2014
Citation: 'phosphatidic acids' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04550 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling   +6 more
wiley   +1 more source

Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min   +8 more
wiley   +1 more source

Editorial Correction

open access: yesJournal of Lipid Research, 1960
Due to a printing error, several lines were incorrectly placed in the Summary to the Bradbeer and Stumpf article, page 214 of the April, 1960, issue of the Journal.
doaj   +1 more source

Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids

open access: yesCells, 2020
Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA methylation across evolution from Archaea to humans. It has been reported that fibrillarin is involved in the methylation of histone H2A in nucleoli and other ...
Francisco Guillen-Chable   +9 more
doaj   +1 more source

x‐Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+‐Stabilized Expanded Active‐Site Cleft Adapted for Phospholipid Binding

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake   +6 more
wiley   +1 more source

Metabolism of glycerolipids: V. Metabolism of phosphatidic acid

open access: yesJournal of Lipid Research, 1964
Monoacyl glycerol phosphate is acylated more rapidly than glycerol-3-phosphate by microsomal preparations from rat or guinea pig liver.Specifically labeled diacyl glycerol phosphate derivatives were prepared.
William E.M. Lands, Priscilla Hart
doaj   +1 more source

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