Results 31 to 40 of about 26,600 (143)
Identification of Key Phospholipids That Bind and Activate Atypical PKCs
Biomedicines, 2021 PKCζ and PKCι/λ form the atypical protein kinase C subgroup, characterised by a lack of regulation by calcium and the neutral lipid diacylglycerol. To better understand the regulation of these kinases, we systematically explored their interactions with ...
Suresh Velnati +10 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley +1 more source
Journal of Lipid Research, 1962 Particulate preparations of rat and pig tissues have been found to catalyze the hydrolysis of lipid phosphates including many alcohol dihydrogen phosphates as well as phosphatidic acids.
Bernard W. Agranoff
doaj +1 more source
Scientific Reports, 2020 Organ cell diversity depends on binary cell-fate decisions mediated by the Notch signalling pathway during development and tissue homeostasis. A clear example is the series of binary cell-fate decisions that take place during asymmetric cell divisions ...
Ignacio Medina-Yáñez +4 more
doaj +1 more source
Plant phospholipid signaling: “in a nutshell”
Journal of Lipid Research, 2009 Since the discovery of the phosphoinositide/phospholipase C (PI/PLC) system in animal systems, we know that phospholipids are much more then just structural components of biological membranes.
Teun Munnik, Christa Testerink
doaj +1 more source
Putting the pH into phosphatidic acid signaling
BMC Biology, 2011 The lipid phosphatidic acid (PA) has important roles in cell signaling and metabolic regulation in all organisms. New evidence indicates that PA also has an unprecedented role as a pH biosensor, coupling changes in pH to intracellular signaling pathways.
Shin John JH, Loewen Christopher JR
doaj +1 more source
Phosphatidic Acid Accumulates at Areas of Curvature in Tubulated Lipid Bilayers and Liposomes
Biomolecules, 2022 Phosphatidic acid (PA) is a signaling lipid that is produced enzymatically from phosphatidylcholine (PC), lysophosphatidic acid, or diacylglycerol. Compared to PC, PA lacks a choline moiety on the headgroup, making the headgroup smaller than that of PC ...
Broderick L. Bills, Michelle K. Knowles
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini +2 more
wiley +1 more source
Food Biomacromolecules, EarlyView.Non‐animal extracellular vesicles as bioactive‐compound carriers: compositional characteristics, engineering strategies, and biofunctions. Abstract Animal‐derived extracellular vesicles (EVs) were widely used for bioactive compound delivery but constrained by complex origins, potential immunogenicity, and pathogen contamination.
Jiahao Yu +6 more
wiley +1 more source
Frontiers in Plant Science, 2012 Previous work has demonstrated that plant leaf polar lipid fatty acid composition varies during the diurnal (dark-light) cycle. Fatty acid synthesis occurs primarily during the light, but fatty acid desaturation continues in the absence of light ...
Sara eMaatta +9 more
doaj +1 more source