Results 21 to 30 of about 3,207 (207)

Spatial Detection of Microsphere Polystyrene Plastics and Molecular Remodeling within a Full‐Body Mouse with MALDI Trapped Ion Mobility Mass Spectrometry Imaging

open access: yesAngewandte Chemie, EarlyView.
Orally administered polystyrene microplastics accumulate in murine tissues and are detected using MALDI‐MSI with TIMS. Lipid profiling reveals decreases in hexosylceramides, sphingomyelins, and ether‐linked phospholipids, indicating altered metabolism.
Karina A. Vargas   +5 more
wiley   +2 more sources

Cellular phosphatidic acid sensor, α-synuclein N-terminal domain, detects endogenous phosphatidic acid in macrophagic phagosomes and neuronal growth cones

open access: yesBiochemistry and Biophysics Reports, 2020
Phosphatidic acid (PA) is the simplest phospholipid and is involved in the regulation of various cellular events. Recently, we developed a new PA sensor, the N-terminal region of α-synuclein (α-Syn-N).
Haruka Yamada   +3 more
doaj   +1 more source

Comprehensive analysis of glycerolipid dynamics during tobacco pollen germination and pollen tube growth

open access: yesFrontiers in Plant Science, 2022
Pollen germination and subsequent pollen tube elongation are essential for successful land plant reproduction. These processes are achieved through well-documented activation of membrane trafficking and cell metabolism. Despite this, our knowledge of the
Natalia Serrano   +4 more
doaj   +1 more source

Phosphatidic acid inhibits SCAB1-mediated F-actin bundling in Arabidopsis

open access: yesPlant Signaling & Behavior, 2023
Stomatal closure-associated actin-binding protein 1 (SCAB1) regulates stomatal closure by mediating actin filament reorganization in Arabidopsis thaliana.
Haiqi Fu   +6 more
doaj   +1 more source

A rapid and sensitive radiochemical assay for phosphatidic acid phosphohydrolase activity

open access: yesJournal of Lipid Research, 1977
A technique is described for the radiochemical assay of phosphatidic acid phosphohydrolase activity in rat brain. Radiochemically pure 32P-labeled phosphatidic acid of known specific radioactivity and structure, which was biosynthesized in vitro by the ...
T J Flynn, D S Deshmukh, R A Pieringer
doaj   +1 more source

A comparative study of eicosapentaenoic acid metabolism by human platelets in vivo and in vitro.

open access: yesJournal of Lipid Research, 1985
During long-term dietary n-3 fatty acid supplementation, eicosapentaenoic acid (EPA) is not incorporated into phosphatidylinositol or -serine of human platelets in vivo and is not detectable in phosphatidic acid upon stimulation with thrombin.
C von Schacky   +3 more
doaj   +1 more source

Application of phosphatidic acid in sport: reality or myth?

open access: yesСпортивная медицина: наука и практика, 2020
The mTOR enzyme plays an important role in the transmission of extracellular signals through the phosphorylation of numerous substrates in various metabolic reactions of the human body.
N. D. Golberg, V. А. Rogozkin
doaj  

New, partially hydrolyzable synthetic analogues of lecithin, phosphatidyl ethanolamine, and phosphatidic acid

open access: yesJournal of Lipid Research, 1966
The synthesis of two new synthetic analogues of lecithin, two of phosphatidyl ethanolamine (``cephalin''), and one new phosphatidic acid analogue is described.
Arthur F. Rosenthal
doaj   +1 more source

The antimicrobial activity of exogeno us anionic phospholipids against Mycobacterium tuberculosis and Escherichia coli

open access: yesТонкие химические технологии, 2016
The effect of anionic phospholipids, namely, cardiolipin, phosphatidylglycerol and phosphatidic acid, on the growth of gram-negative bacteria E. coli BL21(DE3), as well as gram-positive bacteria M. tuberculosis H37Rv was investigated in this study.
Yu. L. Mikulovich   +3 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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