Results 11 to 20 of about 3,207 (207)
Phosphatidic acid synthesis in bacteria [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2013 Membrane phospholipid synthesis is a vital facet of bacterial physiology. Although the spectrum of phospholipid headgroup structures produced by bacteria is large, the key precursor to all of these molecules is phosphatidic acid (PtdOH). Glycerol-3-phosphate derived from the glycolysis via glycerol-phosphate synthase is the universal source for the ...
Jiangwei, Yao, Charles O, Rock
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Mitochondria: Signaling with phosphatidic acid [PDF]
The International Journal of Biochemistry & Cell Biology, 2012 Mitochondria, once viewed as functioning relatively autonomously in the cell, have increasingly been recognized to be involved in numerous signaling networks that impact on a wide range of cell biological processes. In addition to the many types of proteins that mediate these pathways, the importance of signaling functions regulated via lipids and ...
Chia-Ying, Yang, Michael A, Frohman
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PHOSPHATIDIC ACID SYNTHESIS IN YEAST [PDF]
Biochemical Journal, 1965 1. The presence of palmitoyl-CoA-l-glycerol 1-phosphate palmitoyltransferase (EC2.3.1.15) has been demonstrated in a particulate fraction of baker's yeast. 2. The enzyme has been characterized, and its activity studied as a function of pH and concentration of substrates. 3. Inhibition by thiol poisons and protection by acyl-CoA have been used to obtain
N J, KUHN, F, LYNEN
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Phosphatidic acid modulation of Kv channel voltage sensor function
eLife, 2014 Membrane phospholipids can function as potent regulators of ion channel function. This study uncovers and investigates the effect of phosphatidic acid on Kv channel gating.
Richard K Hite +2 more
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Antiviral nucleoside diphosphate diglycerides: improved synthesis and facilitated purification.
Journal of Lipid Research, 1992 Cytidine diphosphate diglyceride and its analogs have previously been synthesized by condensing phosphatidic acid with the monophosphomorpholidates of the various nucleosides. Yields have been low and purification of the product has been difficult.
GM van Wijk +2 more
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Journal of Lipid Research, 1991 Dietary fats are converted into chylomicron triacylglycerols via the 2-monoacylglycerol and phosphatidic acid pathways of acylglycerol formation. In view of the known positional and fatty acid specificity of the acyltransferases, the triacylglycerol ...
LY Yang, A Kuksis
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Journal of Lipid Research, 1979 The acid-catalyzed isomerization of the diglyceride analog (1,2,3/0)-1,2-dipalmitoylcyclopentane-1,2,3-triol has been used to generate syn-syn-1,3-diacyl-cyclopentane-1,2,3-triol, a required intermediate in the synthesis of a symmetrical all-cis-1,2,3/0 ...
A J Hancock, M D Lister
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Enzymatic synthesis of cytidine diphosphate diglyceride
Journal of Lipid Research, 1966 Evidence is presented for the enzymatic formation of cytidine diphosphate diglyceride in microsomal preparations from guinea pig liver according to the reaction:CTP + phosphatidic acid ⇌ CDP-diglyceride + P—O—P.Conditions have been found in which the ...
James R. Carter, Eugene P. Kennedy
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An intracellular motif of GLUT4 regulates fusion of GLUT4-containing vesicles
BMC Cell Biology, 2008 Background Insulin stimulates glucose uptake by adipocytes through increasing translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane.
Welsh Gavin I +5 more
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Journal of Lipid Research, 1960 A phosphatidic acid is the major lipid to become labeled when Pi32 (inorganic orthophosphate labeled with P32), under conditions of oxidative phosphorylation, or ATP32 is fed to mito-choline and phosphatidylethanolamine in the mitochondria obtained a ...
Clive Bradbeer, P.K. Stumpf
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