Results 11 to 20 of about 26,600 (143)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Enzymatic synthesis of cytidine diphosphate diglyceride

open access: yesJournal of Lipid Research, 1966
Evidence is presented for the enzymatic formation of cytidine diphosphate diglyceride in microsomal preparations from guinea pig liver according to the reaction:CTP + phosphatidic acid ⇌ CDP-diglyceride + P—O—P.Conditions have been found in which the ...
James R. Carter, Eugene P. Kennedy
doaj   +1 more source

An intracellular motif of GLUT4 regulates fusion of GLUT4-containing vesicles

open access: yesBMC Cell Biology, 2008
Background Insulin stimulates glucose uptake by adipocytes through increasing translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane.
Welsh Gavin I   +5 more
doaj   +1 more source

Fat metabolism in higher plants: XIII. phosphatidic acid synthesis and diglyceride phosphokinase activity in mitochondria from peanut cotyledons*

open access: yesJournal of Lipid Research, 1960
A phosphatidic acid is the major lipid to become labeled when Pi32 (inorganic orthophosphate labeled with P32), under conditions of oxidative phosphorylation, or ATP32 is fed to mito-choline and phosphatidylethanolamine in the mitochondria obtained a ...
Clive Bradbeer, P.K. Stumpf
doaj   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

open access: yesAngewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao   +8 more
wiley   +2 more sources

Cellular phosphatidic acid sensor, α-synuclein N-terminal domain, detects endogenous phosphatidic acid in macrophagic phagosomes and neuronal growth cones

open access: yesBiochemistry and Biophysics Reports, 2020
Phosphatidic acid (PA) is the simplest phospholipid and is involved in the regulation of various cellular events. Recently, we developed a new PA sensor, the N-terminal region of α-synuclein (α-Syn-N).
Haruka Yamada   +3 more
doaj   +1 more source

Comprehensive analysis of glycerolipid dynamics during tobacco pollen germination and pollen tube growth

open access: yesFrontiers in Plant Science, 2022
Pollen germination and subsequent pollen tube elongation are essential for successful land plant reproduction. These processes are achieved through well-documented activation of membrane trafficking and cell metabolism. Despite this, our knowledge of the
Natalia Serrano   +4 more
doaj   +1 more source

A comparative study of eicosapentaenoic acid metabolism by human platelets in vivo and in vitro.

open access: yesJournal of Lipid Research, 1985
During long-term dietary n-3 fatty acid supplementation, eicosapentaenoic acid (EPA) is not incorporated into phosphatidylinositol or -serine of human platelets in vivo and is not detectable in phosphatidic acid upon stimulation with thrombin.
C von Schacky   +3 more
doaj   +1 more source

Phosphatidic acid inhibits SCAB1-mediated F-actin bundling in Arabidopsis

open access: yesPlant Signaling & Behavior, 2023
Stomatal closure-associated actin-binding protein 1 (SCAB1) regulates stomatal closure by mediating actin filament reorganization in Arabidopsis thaliana.
Haiqi Fu   +6 more
doaj   +1 more source

A rapid and sensitive radiochemical assay for phosphatidic acid phosphohydrolase activity

open access: yesJournal of Lipid Research, 1977
A technique is described for the radiochemical assay of phosphatidic acid phosphohydrolase activity in rat brain. Radiochemically pure 32P-labeled phosphatidic acid of known specific radioactivity and structure, which was biosynthesized in vitro by the ...
T J Flynn, D S Deshmukh, R A Pieringer
doaj   +1 more source

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