Results 81 to 90 of about 47,232 (289)
Regulation of mTOR by Phosphatidic Acid? [PDF]
Cancer Research, 2007 Abstract Interest in the regulation of the mammalian target of rapamycin (mTOR) has increased substantially in recent years largely because of an apparent link between mTOR and survival signals in human cancer cells. Much has been learned about the regulation of mTOR in response to survival signals generated by phosphatidylinositol 3 ...
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Arthritis &Rheumatology, Accepted Article.Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin +15 more
wiley +1 more source
Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids
Cells, 2020 Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA methylation across evolution from Archaea to humans. It has been reported that fibrillarin is involved in the methylation of histone H2A in nucleoli and other ...
Francisco Guillen-Chable +9 more
doaj +1 more source
Hydrophobic cis-platinum complexes efficiently incorporated into liposomes [PDF]
, 1992 The present invention involves the synthesis and use of new platinum compounds. These new platinum compounds are easy to encapsulate in liposomes at high efficiencies.
Khokhar, Abdul R. +2 more
core +3 more sources
Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine
BMEMat, EarlyView.Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo +9 more
wiley +1 more source
Journal of Lipid Research, 1960 Due to a printing error, several lines were incorrectly placed in the Summary to the Bradbeer and Stumpf article, page 214 of the April, 1960, issue of the Journal.
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Metabolism of glycerolipids: V. Metabolism of phosphatidic acid
Journal of Lipid Research, 1964 Monoacyl glycerol phosphate is acylated more rapidly than glycerol-3-phosphate by microsomal preparations from rat or guinea pig liver.Specifically labeled diacyl glycerol phosphate derivatives were prepared.
William E.M. Lands, Priscilla Hart
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Nature Communications, 2021 Apicomplexa generate essential lipids as combination of host fatty acids and de novo synthesized within the apicoplast. Here, the authors identify a phosphatidic acid phosphatase in Toxoplasma gondii, TgLIPIN, as central for controlled lipid synthesis ...
Sheena Dass +9 more
doaj +1 more source
Identification and physiological characterization of phosphatidic acid phosphatase enzymes involved in triacylglycerol biosynthesis in Streptomyces coelicolor [PDF]
, 2013 BACKGROUND: Phosphatidic acid phosphatase (PAP, EC 3.1.3.4) catalyzes the dephosphorylation of phosphatidate yielding diacylglycerol (DAG), the lipid precursor for triacylglycerol (TAG) biosynthesis.
Arabolaza, Ana Lorena +3 more
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, 2014 Citation: 'phosphatidic acids' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04550 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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