Results 131 to 140 of about 30,263 (277)
Cell Proliferation, EarlyView.Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu +8 more
wiley +1 more source
The FEBS Journal, EarlyView.Decidualization is the process by which human endometrial stromal cells undergo morphological and functional changes to prepare the uterus for embryo implantation and support pregnancy. Our study identifies the phosphatidic acid‐Src‐FAK‐RhoA/ROCK signaling pathway as a critical regulator of the cytoskeletal alterations required for this transformation.
Hyeon‐Jeong Jun +5 more
wiley +1 more source
Frontiers in Endocrinology, 2018 Searching for nutraceuticals and understanding the underlying mechanism that promote fish growth is at high demand for aquaculture industry. In this study, the modulatory effects of soy phosphatidic acids (PA) on cell proliferation, nutrient sensing, and
Tingting Wang +12 more
doaj +1 more source
Phosphatidic Acid Synthesis in Escherichia coli [PDF]
, 1969 Makoto Kito, Lewis I. Pizer
openalex +1 more source
A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains
The FEBS Journal, EarlyView.Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley +1 more source
The Formation and Continuous Turnover of a Fraction of Phosphatidic Acid on Stimulation of NaCl Secretion by Acetylcholine in the Salt Gland [PDF]
, 1967 Mabel R. Hokin, Lowell E. Hokin
openalex +1 more source
The FEBS Journal, EarlyView.The membrane‐bound heme flavoprotein MsrQ is the specific electron donor for the periplasmic methionine sulfoxide reductase MsrP. Analysis of its flavin environment revealed that ubiquinone (UQ) is a cofactor for MsrQ. However, redox studies demonstrate that UQ cannot function as an electron donor for the MsrPQ system.
Philippe Carpentier +9 more
wiley +1 more source
Turnover of Phosphatidic Acid and Sodium Extrusion from Mammalian Erythrocytes [PDF]
, 1964 Leonard B. Kirschner, Jennifer M. Barker
openalex +1 more source
Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments
The FEBS Journal, EarlyView.Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis +2 more
wiley +1 more source
Regulation of phosphatidic acid phosphatase
The FASEB Journal, 2010 Phosphatidic acid phosphatase (PAP) catalyzes the dephosphorylation of phosphatidic acid (PA) to yield diacylglycerol (DAG) and Pi. The DAG generated in the reaction is used for the synthesis of triacylglycerol (TAG), and for the synthesis of phosphatidylethanolamine and phosphatidylcholine via the Kennedy pathway.
openaire +2 more sources