Results 111 to 120 of about 6,852,406 (251)

The salt stress-induced LPA response in Chlamydomonas is produced via PLA2 hydrolysis of DGK-generated phosphatidic acid[S]

Journal of Lipid Research, 2011
The unicellular green alga Chlamydomonas has frequently been used as a eukaryotic model system to study intracellular phospholipid signaling pathways in response to environmental stresses.
Steven A. Arisz, Teun Munnik
doaj   +1 more source

Activation of Human Neutrophil NADPH Oxidase by Phosphatidic Acid or Diacylglycerol in a Cell-free System

Journal of Biological Chemistry, 1999
The superoxide-generating neutrophil NADPH oxidase can be activated in cell-free reconstitution systems by several agonists, most notably arachidonic acid and the detergent sodium dodecyl sulfate.
R. Erickson, P. Langel-Peveri, A. Traynor-Kaplan, P. Heyworth, J. Curnutte   +4 more
semanticscholar   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Electron Beam Irradiation Improves the Storage Quality of Passion Fruit by Modulating Membrane Lipid Composition and Enhancing ROS-Scavenging Potential

Foods
This study investigated the impacts of electron beam irradiation (EBI) on the storage quality of passion fruit by regulating membrane lipid composition and reactive oxygen species (ROS)-scavenging capacity.
Yazhen Chen, Yuzhao Lin, Minjun Lin, Xuanjing Jiang, Hongbin Chen   +4 more
doaj   +1 more source

Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating

Small, Volume 22, Issue 55, 1 October 2026.
Precise engineering of cell membrane‐coated nanoparticles (CMNPs) requires coordinated control over particle size, coating integrity, and membrane leaflet orientation. This review integrates key synthesis parameters, assembly strategies, and analytical methods that govern these features, revealing how structural control underpins biomimetic function ...
Jie Lay Lim, Lingqing Zong, Wei Deng, Maria Kavallaris, Zi Gu   +4 more
wiley   +1 more source

Phosphatidic acid, phospholipase D and tumorigenesis

Advances in Biological Regulation, 2014
Phospholipase D (PLD) is a membrane protein with a double role: maintenance of the structural integrity of cellular or intracellular membranes and involvement in cell signaling through the product of the catalytic reaction, PA, and through protein-protein interaction with a variety of partners.
openaire   +2 more sources

Intestinal DHA-PA-PG axis promotes digestive organ expansion by mediating usage of maternally deposited yolk lipids

Nature Communications
Although the metabolism of yolk lipids such as docosahexaenoic acid (DHA) is pivotal for embryonic development, the underlying mechanism remains elusive.
Zhengfang Chen, Mudan He, Houpeng Wang, Xuehui Li, Ruirui Qin, Ding Ye, Xue Zhai, Junwen Zhu, Quanqing Zhang, Peng Hu, Guanghou Shui, Yonghua Sun   +11 more
doaj   +1 more source

Metabolomic insights into Lyme neuroborreliosis: Exploring cerebrospinal fluid for diagnostic clues

Ticks and Tick-Borne Diseases
Lyme neuroborreliosis (LNB), a disseminated manifestation of Lyme borreliosis (LB), arises when Borrelia burgdorferi sensu lato (Bbsl) spirochetes disseminate within the host and damage the peripheral nervous system and meninges, and in rare cases, also ...
Ilari Kuukkanen, Annukka Pietikäinen, Tiia Rissanen, Saija Hurme, Elisa Kortela, Jukka Hytönen, Maarit Karonen   +6 more
doaj   +1 more source

Saturated fatty acid- and/or monounsaturated fatty acid-containing phosphatidic acids selectively interact with heat shock protein 27. [PDF]

J Biol Chem, 2023
Yachida N, Hoshino F, Murakami C, Ebina M, Miura Y, Sakane F.   +5 more
europepmc   +1 more source

Phosphatidic Acid-mediated Phosphorylation of the NADPH Oxidase Component p47-phox

Journal of Biological Chemistry, 1997
Phosphatidic acid (PA), generated by phospholipase D activation, has been linked to the activation of the neutrophil respiratory burst enzyme, NADPH oxidase; however, the intracellular enzyme targets for PA remain unclear. We have recently shown (McPhail,
Kristin A. Waite, R. Wallin, D. Qualliotine-Mann, L. Mcphail   +3 more
semanticscholar   +1 more source