Results 101 to 110 of about 20,811 (292)

Genomic and Physiological Insights Into Heat–Drought Tolerance in Wheat Through GWAS and Phenotypic Evaluation

Plant, Cell &Environment, EarlyView.
ABSTRACT Climate change‐driven heat and drought stresses during reproductive stages significantly threaten wheat productivity. To investigate the genetic and physiological basis of combined heat–drought (HD) tolerance, we evaluated 345 wheat genotypes under three environments of HD stresses, non‐stress glasshouse conditions and a late‐sowing field ...
Jingjuan Zhang, Weinan Xu, Rakshith S. R. Gowda, Joel Johnstone, Malona Alinsug, Abhishek Bohra, Vanika Garg, Annapurna Chitikineni, Dion Bennett, Meixue Zhou, Meiqin Lu, Chengdao Li, Zhong‐Hua Chen, Reyazul Rouf Mir, Rajeev K. Varshney   +14 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Intestinal DHA-PA-PG axis promotes digestive organ expansion by mediating usage of maternally deposited yolk lipids

Nature Communications
Although the metabolism of yolk lipids such as docosahexaenoic acid (DHA) is pivotal for embryonic development, the underlying mechanism remains elusive.
Zhengfang Chen, Mudan He, Houpeng Wang, Xuehui Li, Ruirui Qin, Ding Ye, Xue Zhai, Junwen Zhu, Quanqing Zhang, Peng Hu, Guanghou Shui, Yonghua Sun   +11 more
doaj   +1 more source

Metabolomic insights into Lyme neuroborreliosis: Exploring cerebrospinal fluid for diagnostic clues

Ticks and Tick-Borne Diseases
Lyme neuroborreliosis (LNB), a disseminated manifestation of Lyme borreliosis (LB), arises when Borrelia burgdorferi sensu lato (Bbsl) spirochetes disseminate within the host and damage the peripheral nervous system and meninges, and in rare cases, also ...
Ilari Kuukkanen, Annukka Pietikäinen, Tiia Rissanen, Saija Hurme, Elisa Kortela, Jukka Hytönen, Maarit Karonen   +6 more
doaj   +1 more source

Length and Unsaturation of Fatty Acids of Phosphatidic Acid Determines the Aggregation Rate of Insulin and Modifies the Structure and Toxicity of Insulin Aggregates

, 2022
Phosphatidic acid (PA) is a unique plasma membrane lipid that contains fatty acids (FAs) with different lengths and degrees of unsaturation. Under physiological conditions, PA acts as a second messenger regulating a wide variety of cellular processes. At
Stanislav Rizevsky (12102784), Dmitry Kurouski (160432), Mikhail Matveyenka (12102790)   +2 more
core   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Saturated fatty acid- and/or monounsaturated fatty acid-containing phosphatidic acids selectively interact with heat shock protein 27. [PDF]

J Biol Chem, 2023
Yachida N, Hoshino F, Murakami C, Ebina M, Miura Y, Sakane F.   +5 more
europepmc   +1 more source

Supplementary Figure S2 from mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells [PDF]

, 2023
Tra-Ly Nguyen, Marie‐Julie Nokin, Maxim Egorov, Mercedes Tomé, Clément Bodineau, Carmelo Di Primo, Lætitia Minder, Joanna Wdzieczak‐Bakala, María Concepción Garcia-Alvarez, Jérôme Bignon, Odile Thoison, Bernard Delpech, Georgiana Surpateanu, Yves‐Michel Frapart, Fabienne Peyrot, Kahina Abbas, Silvia Terés, Serge Évrard, Abdel‐Majid Khatib, Pierre Soubeyran, Bogdan I. Iorga, Raúl V. Durán, Pascal Collin   +22 more
openalex   +1 more source

The phosphatidic acid pathway enzyme PlsX plays both catalytic and channeling roles in bacterial phospholipid synthesis

, 2020
PlsX is the first enzyme in the pathway that produces phosphatidic acid in Gram-positive bacteria. It makes acylphosphate from acyl-acyl carrier protein (acyl-ACP) and is also involved in coordinating phospholipid and fatty acid biosyntheses.
Sastre, Diego Emiliano, Benites Pariente, Jhonathan S., Albanesi, Daniela, Gueiros-Filho, Frederico J., De Mendoza, Diego, Pulschen, André A., Machinandiarena, Federico, Basso , Luis G.M., Navarro, Marcos V.A.S., Marques Netto, Caterina G.C.   +9 more
core   +1 more source