Results 131 to 140 of about 20,811 (292)

A study on the phosphatidic acid phase transition parameters

, 1985
Chain length dependence of phosphatidic acid phase transition parameters. There is increasing evidence that phosphatidic acids (PA) play a key role in aggregation, fusion and transport processes in cellular membranes although these molecules are normally
G. Monticelli, F. Tolgyesi
core  

SYNTHESIS OF DIPALMITOYL-L-α-GLYCEROPHOSPHORIC ACID DERIVATIVES, AS POSSIBLE INTERMEDIATES FOR SYNTHESIS OF GLYCERYLPHOSPHATIDES

, 1960
Using Verkade's method for the preparation of DL-α-phosphatidic acids, optically active dipalmitoyl-L-α-phosphatidic acid and its derivatives were prepared in good yield. The free dipalmitoyl-L-α-phosphatidic acid and its dimethyl ester were identical in
N. Z. Stanacev, M. Kates
core   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

The synthesis of acylglycerols, phosphatidic acids, and their precursors under plausible primitive earth conditions

, 1978
The syntheses of glycerol, glycerophosphates, acylglycerols, and phosphatidic acids under presumed primitive Earth conditions was demonstrated. The abiotic synthesis of glycerol was accomplished by reduction of glyceraldehyde with H2S gas at 85[degrees].
Epps, Dennis Earl
core  

Bioartificial Livers Developed From Gene‐Edited Pig Hepatocyte Organoids Improve Amino Acid and Lipid Profiles in the Plasma of Patients With Liver Failure

MedComm, Volume 7, Issue 6, June 2026.
A bioartificial liver (BAL) integrating GGTA1‐knockout porcine hepatocytes and R‐spondin1‐overexpressing endothelial organoids was tested using plasma from patients with acute‐on‐chronic liver failure (ACLF). The BAL system actively modulates amino acid and lipid metabolism, enhances detoxification, partially restores overall metabolic balance, and ...
Yuting He, Yang Deng, Xinglong Zhu, Mengyu Gao, Qin Liu, Wanliu Peng, Yanyan Zhou, Lang Bai, Ji Bao   +8 more
wiley   +1 more source

Spatial Detection of Microsphere Polystyrene Plastics and Molecular Remodeling within a Full‐Body Mouse with MALDI Trapped Ion Mobility Mass Spectrometry Imaging

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Orally administered polystyrene microplastics accumulate in murine tissues and are detected using MALDI‐MSI with TIMS. Lipid profiling reveals decreases in hexosylceramides, sphingomyelins, and ether‐linked phospholipids, indicating altered metabolism.
Karina A. Vargas, Amy L. Parkhurst, Ming‐Fo Hsu, Christopher Hou, Fawaz G. Haj, Elizabeth K. Neumann   +5 more
wiley   +2 more sources

Influence of pH and chain length on the phase transition of phosphatidic acid

, 1985
Phosphatidic acids (PA) are normally minor components in natural membranes but there is increasing evidence that these components play a key role in aggregation, fusion and transport processes in cellular membranes.
G. Monticelli, F. Tolgyesi
core  

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, Volume 183, Issue 12, Page 3173-3194, June 2026.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

Rapid Mitogenic Regulation of the mTORC1 Inhibitor, DEPTOR, by Phosphatidic Acid [PDF]

, 2015
Mee‐Sup Yoon, Christina L. Rosenberger, Cong Wu, Nga Truong, Jonathan V. Sweedler, Jie Chen   +5 more
openalex   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, Volume 48, Issue 3, Page 500-517, June 2026.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source